Universität zu Köln

Wetsch, W. A., Herff, H., Schroeder, D. C., Sander, D., Boettiger, B. W. and Finke, S. R. (2021). Efficiency of different flows for apneic oxygenation when using high flow nasal oxygen application - a technical simulation. BMC Anesthesiol., 21 (1). LONDON: BMC. ISSN 1471-2253

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Abstract

Background Preoxygenation and application of apneic oxygenation are standard to prevent patients from desaturation e.g. during emergency intubation. The time before desaturation occurs can be prolonged by applying high flow oxygen into the airway. Aim of this study was to scientifically assess the flow that is necessary to avoid nitrogen entering the airway of a manikin model during application of pure oxygen via high flow nasal oxygen. Methods We measured oxygen content over a 20-min observation period for each method in a preoxygenated test lung applied to a human manikin, allowing either room air entering the airway in control group, or applying pure oxygen via high flow nasal oxygen at flows of 10, 20, 40, 60 and 80 L/min via nasal cannula in the other groups. Our formal hypothesis was that there would be no difference in oxygen fraction decrease between the groups. Results Oxygen content in the test lung dropped from 97 +/- 1% at baseline in all groups to 43 +/- 1% in the control group (p < 0.001 compared to all other groups), to 92 +/- 1% in the 10 L/min group, 92 +/- 1% in the 20 L/min group, 90 +/- 1% in the 40 L/min group, 89 +/- 0% in the 60 L/min group and 87 +/- 0% in the 80 L/min group. Apart from comparisons 10 l/ min vs. 20 L/min group (p = .715) and 10/L/min vs. 40 L/min group (p = .018), p was < 0.009 for all other comparisons. Conclusions Simulating apneic oxygenation in a preoxygenated manikin connected to a test lung over 20 min by applying high flow nasal oxygen resulted in the highest oxygen content at a flow of 10 L/min; higher flows resulted in slightly decreased oxygen percentages in the test lung.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Wetsch, W. A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Herff, H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schroeder, D. C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Sander, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Boettiger, B. W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Finke, S. R. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-570451
DOI:	10.1186/s12871-021-01461-z
Journal or Publication Title:	BMC Anesthesiol.
Volume:	21
Number:	1
Date:	2021
Publisher:	BMC
Place of Publication:	LONDON
ISSN:	1471-2253
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language VENTILATION Multiple languages Anesthesiology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/57045