Universität zu Köln

Medeiros, Tania C., Mehra, Chahat ORCID: 0000-0003-3338-1527 and Pernas, Lena ORCID: 0000-0002-4337-3435 (2021). Contact and competition between mitochondria and microbes. Curr. Opin. Microbiol., 63. S. 189 - 195. LONDON: CURRENT BIOLOGY LTD. ISSN 1879-0364

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Abstract

Invading microbes occupy the host cytosol and take up nutrients on which host organelles are also dependent. Thus, host organelles are poised to interact with intracellular microbes. Despite the essential role of host mitochondria in cellular metabolic homeostasis and in mediating cellular responses to microbial infection, we know little of how these organelles interact with intracellular pathogens, and how such interactions affect disease pathogenesis. Here, we give an overview of the different classes of physical and metabolic interactions reported to occur between mitochondria and eukaryotic pathogens. Investigating the underlying molecular mechanisms and functions of such interactions will reveal novel aspects of infection biology.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Medeiros, Tania C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Mehra, Chahat UNSPECIFIED orcid.org/0000-0003-3338-1527 UNSPECIFIED Pernas, Lena UNSPECIFIED orcid.org/0000-0002-4337-3435 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-571768
DOI:	10.1016/j.mib.2021.07.014
Journal or Publication Title:	Curr. Opin. Microbiol.
Volume:	63
Page Range:	S. 189 - 195
Date:	2021
Publisher:	CURRENT BIOLOGY LTD
Place of Publication:	LONDON
ISSN:	1879-0364
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PARASITE TOXOPLASMA-GONDII; PARASITOPHOROUS VACUOLE; INTRACELLULAR GROWTH; HIGH-AFFINITY; LIPOIC ACID; METABOLISM; GLUTAMINE; CELLS; ASSOCIATION; TRANSPORTER Multiple languages Microbiology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/57176