Universität zu Köln

Xie, Minyue, Li, Tianyuan, Luo, Yingxiu, Li, Yinwei, Wang, Yefei, Fan, Xianqun, Heindl, Ludwig M. and Jia, Renbing (2022). Intralesional diode laser pretreatment facilitates surgery for orbital venous malformations: initial experience with 23 consecutive patients. Graefes Arch. Clin. Exp. Ophthalmol., 260 (1). S. 303 - 310. NEW YORK: SPRINGER. ISSN 1435-702X

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Abstract

Purpose This study aims to evaluate the efficacy and safety of intralesional diode laser pretreatment for facilitating surgery for orbital venous malformations (OVMs). Methods This is a retrospective, non-comparative, interventional cohort involving 23 consecutive OVM patients undergoing intralesional laser pretreatment followed by surgical excision. The main outcome measures included volumetric changes, exophthalmometry, cosmesis, and symptom scores as well as treatment-related adverse events. Results Following intralesional diode laser, the mean volume dropped significantly from 2366 +/- 1887 to 129 +/- 119 mm(3) (t = 5.716; p < 0.001). After a single treatment session, a mean 90 +/- 13% volume shrinkage was achieved in all 23 OVM. The mean Hertel exophthalmometry decreased significantly from 14 +/- 3 to 13 +/- 1 mm (t = 2.515; P < 0.02). The resolution of periocular dyschromasia and swelling were evident in 20 patients (87%). Symptom scores improved significantly from 6.5 +/- 1.4 (very intense discomfort or effect on daily living) to 1.2 +/- 1.0 (very mild discomfort or effect on daily living; p < 0.001). Short-term bruises and swelling were reported in 20 patients (87%). Conclusion Intralesional laser pretreatment is effective to facilitate surgery especially for the deep involving orbital venous malformations.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Xie, Minyue UNSPECIFIED UNSPECIFIED UNSPECIFIED Li, Tianyuan UNSPECIFIED UNSPECIFIED UNSPECIFIED Luo, Yingxiu UNSPECIFIED UNSPECIFIED UNSPECIFIED Li, Yinwei UNSPECIFIED UNSPECIFIED UNSPECIFIED Wang, Yefei UNSPECIFIED UNSPECIFIED UNSPECIFIED Fan, Xianqun UNSPECIFIED UNSPECIFIED UNSPECIFIED Heindl, Ludwig M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Jia, Renbing UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-575487
DOI:	10.1007/s00417-021-05272-3
Journal or Publication Title:	Graefes Arch. Clin. Exp. Ophthalmol.
Volume:	260
Number:	1
Page Range:	S. 303 - 310
Date:	2022
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1435-702X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SURGICAL EXCISION; THERMAL-DAMAGE; EMBOLIZATION; VEIN; ABSORPTION; DIAGNOSIS; VARICES Multiple languages Ophthalmology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/57548