Universität zu Köln

Gietzelt, Caroline, Kiessling, David, Widder, Randolf A., Heindl, Ludwig M., Cursiefen, Claus, Dietlein, Thomas S. and Enders, Philip (2021). Combined ab-interno trabeculectomy and cataract surgery induces comparable intraocular pressure reduction in supine and sitting positions. Int. J. Ophthalmol., 14 (8). S. 1192 - 1199. XI AN: IJO PRESS. ISSN 2227-4898

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Abstract

AIM: To analyze the therapeutic effect of combined abinterno trabeculectomy and cataract surgery on intraocular pressure (IOP) levels in supine and sitting postures during a 24-hour IOP profile. METHODS: Twenty-six eyes of twenty-six patients receiving ab-interno trabeculectomy using electroablation of the trabecular meshwork combined with cataract surgery or stand-alone were included in this retrospective analysis. 10P change during 24-hour IOP profiles within two years postoperatively were analyzed for eyes receiving surgery (study eyes) and compared to fellow eyes, which had not received surgery. Clinical data including mean sitting IOP (siIOP), mean supine IOP (suIOP) and the number of topical antiglaucomatous medications (TAM) were extracted from patients' files. RESULTS: Preoperatively, siIOP was 17.6 +/- 5.3 mm Hg in study and 17.1 +/- 4.7 mm Hg in fellow eyes (P=0.347). Patients were treated with an average of 2.8 +/- 1.0 TAM. Best corrected visual acuity (BCVA) was significantly worse in study eyes (P<0.001), visual field function was marginally not significantly different (P=0.057). After surgery 9.6 +/- 6.8mo, study eyes had a mean siIOP of 14.5 +/- 3.6 mm Hg (IOP reduction: -3.2 mm Hg, P=0.009), a mean suIOP of 18.0 +/- 3.5 mm Hg, and an average of 1.3 +/- 1.34 TAM (P<0.001), while in fellow eyes, mean siIOP was 16.2 +/- 3.4 mm Hg and mean suIOP was 20.5 +/- 5.1 mm Hg. Postoperatively, the relative IOP increase between sitting and supine postures was approximately 30% in both study and fellow eyes (P=0.99). CONCLUSION: IOP after ab-interno trabeculectomy shows a comparable relative reduction in both supine and sitting position. Classical trabeculectomy is known to lower suIOP overproportionally.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Gietzelt, Caroline UNSPECIFIED UNSPECIFIED UNSPECIFIED Kiessling, David UNSPECIFIED UNSPECIFIED UNSPECIFIED Widder, Randolf A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Heindl, Ludwig M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Cursiefen, Claus UNSPECIFIED UNSPECIFIED UNSPECIFIED Dietlein, Thomas S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Enders, Philip UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-575654
DOI:	10.18240/ijo.2021.08.09
Journal or Publication Title:	Int. J. Ophthalmol.
Volume:	14
Number:	8
Page Range:	S. 1192 - 1199
Date:	2021
Publisher:	IJO PRESS
Place of Publication:	XI AN
ISSN:	2227-4898
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language POSTURAL CHANGES; GLAUCOMA; FLUCTUATIONS; PROGRESSION; TRABECTOME Multiple languages Ophthalmology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/57565