Niecke, Alexander ORCID: 0000-0002-4042-6693, Ramesh, Irene, Albus, Christian, Lungen, Markus, Pfaff, Holger
ORCID: 0000-0001-9154-6575, Samel, Christina and Peters, Klaus M.
(2021).
Chronic Pain in People Impaired by Thalidomide Embryopathy: An Explorative Analysis of Prevalence, Pain Parameters and Biopsychosocial Factors.
Psychother. Psychosom. Med. Psychol., 71 (09/10).
S. 370 - 381.
STUTTGART:
GEORG THIEME VERLAG KG.
ISSN 1439-1058
Abstract
Objective The aim of the study was to show the frequency, localisation, intensity, quality and degree of chronic pain in people with thalidomide-induced congenital defects (thalidomide embryopathy) and to investigate the association with biopsychosocial factors more closely. Methods A group of 202 people from North Rhine-Westphalia with thalidomide embryopathy were studied for the first time both physically for the pattern of the original damage and also psychiatrically in a structured diagnostic interview (SCID & SCID II). The results were combined with a standardized pain interview ( MPSS) and questionnaires on further pain-related (SF-36, painDETECT) and sociodemographic variables and analysed. In the analysis 167 completed datasets were included. Results The prevalence of pain in the sample population was 94 %. The majority (107, 54.0 %) already showed an advanced stage of chronicity in the MPSS: 63 subjects with Stage II (37.7 %) and 44 with Stage III (26.3 %). In 74 subjects (44.3 %) the PainDetect score showed a possible or neuropathic pain component. The factors that most reliably influenced the chronicity of pain proved to be hip pain (p < 0.001) and also mental health disorders (p = 0.001), above major depression (p < 0.001) and also somatic symptom disorders and substance-related disorders (p = 0.001 in each case). Social variables proved nonsignificant here (p = 0.094 for living alone, p = 0.122 for unemployment, p = 0.167 for lack of college education), as did the care situation (p = 0.191 for care dependency) and the underlying pattern of organ damage (p = 0.229 for damage to hearing, p = 0.764 for dysmelia). Conclusions People with thalidomide defects frequently suffer from a separate pain disorder which can be seen as secondary thalidomide-induced damage and which requires specialized and personalized multimodal pain management.
Item Type: | Journal Article | ||||||||||||||||||||||||||||||||
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URN: | urn:nbn:de:hbz:38-575702 | ||||||||||||||||||||||||||||||||
DOI: | 10.1055/a-1457-2846 | ||||||||||||||||||||||||||||||||
Journal or Publication Title: | Psychother. Psychosom. Med. Psychol. | ||||||||||||||||||||||||||||||||
Volume: | 71 | ||||||||||||||||||||||||||||||||
Number: | 09/10 | ||||||||||||||||||||||||||||||||
Page Range: | S. 370 - 381 | ||||||||||||||||||||||||||||||||
Date: | 2021 | ||||||||||||||||||||||||||||||||
Publisher: | GEORG THIEME VERLAG KG | ||||||||||||||||||||||||||||||||
Place of Publication: | STUTTGART | ||||||||||||||||||||||||||||||||
ISSN: | 1439-1058 | ||||||||||||||||||||||||||||||||
Language: | German | ||||||||||||||||||||||||||||||||
Faculty: | Unspecified | ||||||||||||||||||||||||||||||||
Divisions: | Unspecified | ||||||||||||||||||||||||||||||||
Subjects: | no entry | ||||||||||||||||||||||||||||||||
Uncontrolled Keywords: |
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URI: | http://kups.ub.uni-koeln.de/id/eprint/57570 |
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