Stemler, Jannik ORCID: 0000-0001-9152-2469, Kramer, Theresa, Dimitriou, Vassiliki, Wieland, Ulrike, Schumacher, Sofie, Sprute, Rosanne ORCID: 0000-0003-2457-6437, Oberste, Max, Wiesmuller, Gerhard, Rau, Harald, Pieper, Sally, Bethe, Ullrich ORCID: 0000-0001-9979-1671, Lehmann, Clara, Hellmich, Martin, Klein, Florian, Langebartels, Georg and Cornely, Oliver A. . Mobile PCR-based surveillance for SARS-CoV-2 to reduce visiting restrictions in nursing homes during the COVID-19 pandemic: a pilot study. Infection. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1439-0973

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Abstract

Purpose Residents in nursing homes for the elderly (NH) are at high risk for death from COVID-19. We investigated whether repeated non-mandatory RT-PCR SARS-CoV-2 surveillance of NH staff and visitors reduces COVID-19 incidence rates in NH residents and allows to reduce visiting restrictions. Methods This pilot study at the beginning of the COVID-19 pandemic compared a surveillance approach of regular, twice-weekly voluntary PCR testing of health-care workers (HCW) and visitors in interventional NH (INH) with a setting without regular testing in control NH (CNH). Residents were not tested routinely within this study. Testing was performed in a mobile testing site with same-day result reporting. SARS-CoV-2 incidence among residents in both INH and CNH was the primary endpoint; secondary endpoints being SARS-CoV-2 infection among visitors and HCW in INH. Results Two INH and two CNH participated between October and December, 2020. At INH1, 787 tests of HCW and 350 tests of visitors were performed, accounting for 18.1% (n = 1930) of visits. At INH2, 78 tests of HCW and 372 tests of visitors were done, i.e., 30.5% (n = 1220) of visits. At the two INH 23 HCW and three visitors tested positive for SARS-CoV-2. COVID-19 outbreaks occurred among residents in INH1 (identified through study testing) and in CNH1. Utilization of voluntary testing was low. Conclusion In a real-world setting without available rapid testing, voluntary RT-PCR SARS-CoV-2 testing of HCW and visitors does not prevent COVID-19 outbreaks in NH. Complete, non-selective testing for these groups should be instituted before visiting restrictions can be reduced.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Stemler, JannikUNSPECIFIEDorcid.org/0000-0001-9152-2469UNSPECIFIED
Kramer, TheresaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dimitriou, VassilikiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wieland, UlrikeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schumacher, SofieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sprute, RosanneUNSPECIFIEDorcid.org/0000-0003-2457-6437UNSPECIFIED
Oberste, MaxUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wiesmuller, GerhardUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rau, HaraldUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pieper, SallyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bethe, UllrichUNSPECIFIEDorcid.org/0000-0001-9979-1671UNSPECIFIED
Lehmann, ClaraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hellmich, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Klein, FlorianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Langebartels, GeorgUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cornely, Oliver A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-577242
DOI: 10.1007/s15010-021-01716-4
Journal or Publication Title: Infection
Publisher: SPRINGER HEIDELBERG
Place of Publication: HEIDELBERG
ISSN: 1439-0973
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
MORTALITY; AGEMultiple languages
Infectious DiseasesMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/57724

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