Universität zu Köln

Zaeske, Charlotte ORCID: 0000-0003-3746-8523, Goertz, Lukas, Dorn, Franziska, Turowski, Bernd, Abdullayev, Nuran ORCID: 0000-0003-4522-537X, Schlamann, Marc, Liebig, Thomas and Kabbasch, Christoph ORCID: 0000-0003-3712-2258 (2021). Comparative Analysis of the Pipeline and the Derivo Flow Diverters for the Treatment of Unruntured Intracranial Aneurysms-A Multicentric Study. World Neurosurg., 145. S. E326 - 6. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1878-8769

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Abstract

OBJECTIVE: Flow diversion represents a sate and efficient technique for the endovascular treatment of complex intracranial aneurysms. This study compares 2 competing flow diverters, the Pipeline embolization device (PED) and the Derivo Embolization Device (DED) regarding technical aspects, clinical outcome, and angiographic results. METHODS: A total of 111 patients with unruptured aneurysms were treated with the PED (n = 62) or the DED (n = 49) between 2011 and 2019. Procedural specifics, complication rates, functional outcome, and aneurysm occlusion were evaluated retrospectively. RESULTS: Flow-diverter implantation was technically successful in all patients. There were no significant differences regarding baseline characteristics, adjunctive coiling, and fluoroscopy time. Multiple devices were more often used in the PED group (35.6%) than in the DED group (4.1%, P < 0.001). Procedural adverse events occurred in 4 cases of each group (PED: 5.5%, DED: 8.2%, P = 0.713), including 3 thromboembolic events and 1 hemorrhagic event per group. Morbidity rates were similar between the 2 groups (PED: 2.7%, DED: 4.1%, P = 1.0). There was no procedural mortality. At 6-month follow-up, complete or near-complete occlusion (O'Kelly-Marotta scale C+ D) was achieved in 79.0% (49/62) after PED implantation and 80.0% (32/40) after DED implantation (P = 0.354). CONCLUSIONS: In regard to complication rates, functional outcome, and aneurysm occlusion, no significant differences were found between the PED and DED collective.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Zaeske, Charlotte UNSPECIFIED orcid.org/0000-0003-3746-8523 UNSPECIFIED Goertz, Lukas UNSPECIFIED UNSPECIFIED UNSPECIFIED Dorn, Franziska UNSPECIFIED UNSPECIFIED UNSPECIFIED Turowski, Bernd UNSPECIFIED UNSPECIFIED UNSPECIFIED Abdullayev, Nuran UNSPECIFIED orcid.org/0000-0003-4522-537X UNSPECIFIED Schlamann, Marc UNSPECIFIED UNSPECIFIED UNSPECIFIED Liebig, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Kabbasch, Christoph UNSPECIFIED orcid.org/0000-0003-3712-2258 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-579631
DOI:	10.1016/j.wneu.2020.10.062
Journal or Publication Title:	World Neurosurg.
Volume:	145
Page Range:	S. E326 - 6
Date:	2021
Publisher:	ELSEVIER SCIENCE INC
Place of Publication:	NEW YORK
ISSN:	1878-8769
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EMBOLIZATION DEVICE; COMPLICATIONS; DIVERSION Multiple languages Clinical Neurology; Surgery Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/57963