Universität zu Köln

Zhou, Chenghui ORCID: 0000-0003-1170-1761, Zhang, Yiwei, Hu, Xi, Fang, Min and Xiao, Shuai (2021). The effect of marital and insurance status on the survival of elderly patients with stage M1b colon cancer: a SEER-based study. BMC Cancer, 21 (1). LONDON: BMC. ISSN 1471-2407

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Abstract

BackgroundColon cancer is largely implicated in elderly patients (age >= 60years). The prognosis of patients diagnosed with the M1b stage is vastly poor. Marital and insurance status has been considered important prognostic factors in various cancer types. However, how these factors influence elderly patients with stage M1b colon cancer remains to be explored. This study aims to uncover the role of marital and insurance status in the survival of elderly patients with stage M1b colon cancer.MethodsWe retrieved data for patients diagnosed with stage M1b colon cancer between 2010 and 2016 from the Surveillance, Epidemiology, and End Results (SEER) database. Our analysis of the clinicopathological features, overall survival (OS), and cancer-specific survival (CSS) was based on the marital and insurance status, respectively.ResultsIn sum, 5709 stage M1b colon cancer patients with complete information from SEER were enrolled for analysis. The OS and CSS of the Non-married group were poorer compared to that of the Married group. The OS and CSS of the Uninsured group were poorer than both of the Insured group and Medicaid group. However, OS was comparable between Uninsured group and Medicaid groups. The findings allude that marital and insurance status potentially impact the long-term survival of elderly patients with M1b colon cancer. The subgroup survival analyses revealed the lowest risk for death among the Insured Married group based on the comparison of the OS and CSS across all other groups. Moreover, Univariate and multivariate analyses revealed race, marital status, surgery, and chemotherapy as independent predictors for OS, whereas insurance status, surgery,and chemotherapy were independent predictors for CSS in elderly patients with M1b colon cancer.ConclusionThe marital and insurance status greatly impact the survival of elderly patients with M1b colon cancer. Therefore, it is imperative to provide more support to this vulnerable patient group who are lonely and uninsured, particularly in the psychological and health insurance aspect.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Zhou, Chenghui UNSPECIFIED orcid.org/0000-0003-1170-1761 UNSPECIFIED Zhang, Yiwei UNSPECIFIED UNSPECIFIED UNSPECIFIED Hu, Xi UNSPECIFIED UNSPECIFIED UNSPECIFIED Fang, Min UNSPECIFIED UNSPECIFIED UNSPECIFIED Xiao, Shuai UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-582462
DOI:	10.1186/s12885-021-08627-5
Journal or Publication Title:	BMC Cancer
Volume:	21
Number:	1
Date:	2021
Publisher:	BMC
Place of Publication:	LONDON
ISSN:	1471-2407
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PSYCHOLOGICAL-STRESS; HEALTH; IMPACT Multiple languages Oncology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/58246