Universität zu Köln

Pinto-Fraga, Jose, Calonge, Margarita, Enriquez-de-Salamanca, Amalia, Fernandez, Itziar, Gonzalez-Garcia, Maria J. and Steven, Philipp ORCID: 0000-0001-6892-3619 (2021). Development of a Questionnaire for Detecting Changes in Dry Eye Disease-Related Symptoms. Eye Contact Lens-Sci. Clin. Pra., 47 (1). S. 8 - 15. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1542-233X

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Abstract

Objectives: Determining the changes in symptomatology suffered by dry eye disease (DED) patients after an intervention is difficult because there is only one validated questionnaire specifically designed to measure these changes and it is somewhat complex. This work uses a simplified questionnaire to evaluate the changes in DED-related symptoms. Methods: A new questionnaire based on a global rating of change scale was designed. The Change in Dry Eye Symptoms Questionnaire (CDES-Q) consists of 2 questions: CDES-Q1 asks for the change in symptoms (better, same, or worse) relative to a determined previous time and CDES-Q2 quantifies this change (range: 0 to +100). To evaluate the CDES-Q, a prospective observational study was performed. At baseline (V1; day-0), DED-related symptoms were evaluated using the ocular surface disease index (OSDI). In the post-treatment visit (V2; day-90), OSDI, Symptoms Assessment Questionnaire in Dry Eye (SANDE) II, and CDES-Q were used. Also, clinical evaluations were performed in each visit. Results: Thirty-six patients were included. At V2, OSDI, SANDE II, and CDES-Q showed a significant reduction in symptoms (-7.17 +/- 12.73, P=0.0021; -11.29 +/- 20.95, P=0.0035; -25.28 +/- 42.28, P=0.0011, respectively). Patients who answered better in CDES-Q1 showed a significantly lower SANDE II than those who answered same or worse, while SANDE II did not discriminate between these groups. Conclusions: CDES-Q can be a useful tool for the evaluation of changes in DED-related symptoms. It is simple and better discriminates patients without changes from those who suffered a worsening than SANDE II.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Pinto-Fraga, Jose UNSPECIFIED UNSPECIFIED UNSPECIFIED Calonge, Margarita UNSPECIFIED UNSPECIFIED UNSPECIFIED Enriquez-de-Salamanca, Amalia UNSPECIFIED UNSPECIFIED UNSPECIFIED Fernandez, Itziar UNSPECIFIED UNSPECIFIED UNSPECIFIED Gonzalez-Garcia, Maria J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Steven, Philipp UNSPECIFIED orcid.org/0000-0001-6892-3619 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-582696
DOI:	10.1097/ICL.0000000000000693
Journal or Publication Title:	Eye Contact Lens-Sci. Clin. Pra.
Volume:	47
Number:	1
Page Range:	S. 8 - 15
Date:	2021
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1542-233X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SIGNS; PAIN; MODERATE; THERAPY; SCALES Multiple languages Ophthalmology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/58269