Universität zu Köln

Schild, Ann-Katrin, Volk, Jenny, Scharfenberg, Daniel ORCID: 0000-0003-2781-3143, Schuermann, Katrin, Meiberth, Dix, Onur, Oezguer A., Jessen, Frank and Maier, Franziska ORCID: 0000-0002-9335-9594 (2021). Social Cognition in Patients with Amnestic Mild Cognitive Impairment and Mild Dementia of the Alzheimer Type. J. Alzheimers Dis., 83 (3). S. 1173 - 1187. AMSTERDAM: IOS PRESS. ISSN 1875-8908

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Abstract

Background: Social cognition (SC) is a core criterion for neurocognitive disorders. However, findings in patients with amnestic mild cognitive impairment (aMCI) and dementia of the Alzheimer type (DAT) are inconsistent. Objective: We report assessments of emotion recognition (ER), affective and cognitive theory of mind (ToM) in young (YC) and older controls (OC) compared to aMCI and DAT. Methods: 28 aMCI, 30 DAT, 30 YC, and 29 OC received tests of SC and a comprehensive neuropsychological assessment. Analysis of covariance was used to determine group differences. Multiple regression models were applied to identify predictors for each SC task. Results: In controls, OC performed worse in ER and both ToM tasks compared to YC except for one subtest. No significant differences were found between OC and patients concerning ER and affective ToM. In cognitive ToM, differences between OC and patients depended on content and cognitive load with significant impairment in DAT compared to OC. A cognitive composite score predicted SC in OC, but not in patients. Associations of SC with single cognitive domains were found in all groups with language and complex attention as best predictors. Not all variance of SC performance was explained by variance in cognitive domains. Conclusion: Lower performance on SC tasks in OC versus YC was confirmed, although not all tasks were equally affected. With progressive cognitive impairment, cognitive ToM is more impaired than ER or affective ToM. SC seems to be at least partly independent of other cognitive domains, justifying its inclusion in batteries for dementia diagnostic.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schild, Ann-Katrin UNSPECIFIED UNSPECIFIED UNSPECIFIED Volk, Jenny UNSPECIFIED UNSPECIFIED UNSPECIFIED Scharfenberg, Daniel UNSPECIFIED orcid.org/0000-0003-2781-3143 UNSPECIFIED Schuermann, Katrin UNSPECIFIED UNSPECIFIED UNSPECIFIED Meiberth, Dix UNSPECIFIED UNSPECIFIED UNSPECIFIED Onur, Oezguer A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Jessen, Frank UNSPECIFIED UNSPECIFIED UNSPECIFIED Maier, Franziska UNSPECIFIED orcid.org/0000-0002-9335-9594 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-584127
DOI:	10.3233/JAD-201126
Journal or Publication Title:	J. Alzheimers Dis.
Volume:	83
Number:	3
Page Range:	S. 1173 - 1187
Date:	2021
Publisher:	IOS PRESS
Place of Publication:	AMSTERDAM
ISSN:	1875-8908
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EMOTION RECOGNITION; BEHAVIORAL-VARIANT; FRONTOTEMPORAL DEMENTIA; ASSOCIATION WORKGROUPS; DIAGNOSTIC GUIDELINES; FACIAL EXPRESSIONS; NATIONAL INSTITUTE; MIND; DISEASE; RECOMMENDATIONS Multiple languages Neurosciences Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/58412