Universität zu Köln

Becher, Marc Ulrich, Balata, Mahmoud, Hesse, Michaela ORCID: 0000-0002-2082-8513, Draht, Fabian, Zachoval, Christian, Weltermann, Birgitta, Westenfeld, Ralf, Neukirchen, Martin, Pfister, Roman, Standl, Thomas, Radbruch, Lukas and Nickenig, Georg . Rationale and design of the EPCHF trial: the early palliative care in heart failure trial (EPCHF). Clin. Res. Cardiol.. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1861-0692

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Abstract

The progressive nature of heart failure (HF) coupled with high mortality and poor quality-of-life (QoL) mandates greater attention to palliative care (PC) as a routine component of HF management. Limited evidence exists from randomized controlled trials supporting the use of interdisciplinary palliative care in the progressive course of HF. The early palliative care in heart failure trial (EPCHF) is a prospective, controlled, nonblinded, multicenter study of an interdisciplinary palliative care intervention in 200 patients with symptomatic HF characterized by NYHA >= 2. The 12-month EPCHF intervention includes monthly consultations by a palliative care team focusing on physical and psychosocial symptom relief, attention to spiritual concerns and advance care planning. The primary endpoint is evaluated by health-related QoL questionnaires after 12 months of treatment. First the functional assessment of chronic illness therapy palliative care (FACIT-Pal) score evaluating QoL living with a chronic disease and second the Kansas City cardiomyopathy questionnaire (KCCQ) measuring QoL living with heart failure will be determined. Secondary endpoints are changes in anxiety/depression (HADS), symptom burden score (MIDOS), spiritual well-being functional assessment of chronic illness therapy spiritual well-being scale (FACIT-Sp), medical resource and cost assessment. EPCHF will help evaluate the efficacy and cost-effectiveness of palliative care in symptomatic HF using a patient-centered outcome as well as clinical and economic endpoints. EPCHF is funded by the Bundesministerium fur Bildung und Forschung (BMBF, 01GY17).

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Becher, Marc Ulrich UNSPECIFIED UNSPECIFIED UNSPECIFIED Balata, Mahmoud UNSPECIFIED UNSPECIFIED UNSPECIFIED Hesse, Michaela UNSPECIFIED orcid.org/0000-0002-2082-8513 UNSPECIFIED Draht, Fabian UNSPECIFIED UNSPECIFIED UNSPECIFIED Zachoval, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Weltermann, Birgitta UNSPECIFIED UNSPECIFIED UNSPECIFIED Westenfeld, Ralf UNSPECIFIED UNSPECIFIED UNSPECIFIED Neukirchen, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Pfister, Roman UNSPECIFIED UNSPECIFIED UNSPECIFIED Standl, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Radbruch, Lukas UNSPECIFIED UNSPECIFIED UNSPECIFIED Nickenig, Georg UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-584780
DOI:	10.1007/s00392-021-01903-1
Journal or Publication Title:	Clin. Res. Cardiol.
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1861-0692
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language QUALITY-OF-LIFE; FUNCTIONAL ASSESSMENT; COMMUNICATION-SKILLS; SYMPTOM BURDEN; DEPRESSION; PATIENT; ASSOCIATION; THERAPY; ILLNESS; CONSULTATION Multiple languages Cardiac & Cardiovascular Systems Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/58478