Universität zu Köln

Athanasopoulos, Fotios, Saprikis, Orionas-Vasilis, Margeli, Myrto, Klein, Christoph and Smyrnis, Nikolaos (2021). Towards Clinically Relevant Oculomotor Biomarkers in Early Schizophrenia. Front. Behav. Neurosci., 15. LAUSANNE: FRONTIERS MEDIA SA. ISSN 1662-5153

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Abstract

In recent years, psychiatric research has focused on the evaluation and implementation of biomarkers in the clinical praxis. Oculomotor function deviances are among the most consistent and replicable cognitive deficits in schizophrenia and have been suggested as viable candidates for biomarkers. In this narrative review, we focus on oculomotor function in first-episode psychosis, recent onset schizophrenia as well as individuals at high risk for developing psychosis. We critically discuss the evidence for the possible utilization of oculomotor function measures as diagnostic, susceptibility, predictive, monitoring, and prognostic biomarkers for these conditions. Based on the current state of research we conclude that there are not sufficient data to unequivocally support the use of oculomotor function measures as biomarkers in schizophrenia.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Athanasopoulos, Fotios UNSPECIFIED UNSPECIFIED UNSPECIFIED Saprikis, Orionas-Vasilis UNSPECIFIED UNSPECIFIED UNSPECIFIED Margeli, Myrto UNSPECIFIED UNSPECIFIED UNSPECIFIED Klein, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED Smyrnis, Nikolaos UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-588003
DOI:	10.3389/fnbeh.2021.688683
Journal or Publication Title:	Front. Behav. Neurosci.
Volume:	15
Date:	2021
Publisher:	FRONTIERS MEDIA SA
Place of Publication:	LAUSANNE
ISSN:	1662-5153
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EXPLORATORY EYE-MOVEMENTS; ANTISACCADE TASK-PERFORMANCE; WORKING-MEMORY TASK; HIGH-RISK STATE; SMOOTH-PURSUIT; TRACKING DYSFUNCTION; INTERMEDIATE PHENOTYPE; 1ST-DEGREE RELATIVES; TEMPORAL STABILITY; AFFECTIVE-DISORDER Multiple languages Behavioral Sciences; Neurosciences Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/58800