Universität zu Köln

Fathi, Anahita and Mellinghoff, Sibylle C. (2021). Vaccines against COVID-19. Internist, 62 (11). S. 1191 - 1202. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-1289

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Abstract

The ongoing COVID-19 pandemic represents an emergency situation of devastating proportions. To mitigate its effects, several safe and effective vaccines have been developed in a very short period of time. Currently, four vaccines have been approved by the European Medicines Agency (EMA) and are in use in Germany. These include two mRNA vaccines and two vector-based vaccines. They all show very good protective efficacy, especially against severe courses of disease and can significantly contain the pandemic by reducing viral transmission. This article focuses on the development and mechanism of action of the vaccines, their safety and efficacy profile as well as indications for vaccination and current recommendations for the use of vaccines in special groups of people, such as convalescent, immunosuppressed and pregnant patients. Finally, currently open scientific questions are addressed.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Fathi, Anahita UNSPECIFIED UNSPECIFIED UNSPECIFIED Mellinghoff, Sibylle C. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-588181
DOI:	10.1007/s00108-021-01164-0
Journal or Publication Title:	Internist
Volume:	62
Number:	11
Page Range:	S. 1191 - 1202
Date:	2021
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1432-1289
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SEASONAL INFLUENZA; VACCINATION; CANCER Multiple languages Medicine, General & Internal Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/58818