Universität zu Köln

Bockler, Adeline, Ferrari, Nina, Deibert, Clara, Flock, Anne, Merz, Waltraut M., Gembruch, Ulrich ORCID: 0000-0001-8284-4669, Ehrhardt, Christina, Dotsch, Jorg and Joisten, Christine (2021). Relationship between Physical Activity and the Metabolic, Inflammatory Axis in Pregnant Participants. Int. J. Environ. Res. Public Health, 18 (24). BASEL: MDPI. ISSN 1660-4601

Full text not available from this repository.

Abstract

Physical activity (PA) during pregnancy is beneficial for mother and child. Little is known regarding the effects of PA on specific adipokines/myokines and their impact during pregnancy. This study investigates the correlation between PA during late pregnancy, body composition, and maternal levels of leptin, IL-6, and TNF-alpha at delivery. In a cross-sectional study of 91 pregnant participants (mean age 33.9 +/- 4.6 years) without gestational diabetes mellitus or preeclampsia, anthropometric data and blood samples were taken at delivery. PA during the third trimester was measured via the Pregnancy Physical Activity Questionnaire. Activities were ranked by intensity: sedentary (<1.5 metabolic equivalent (METs)), light (1.5-3.0 METs), moderate (3.0-6.0 METs), and vigorous activity (>6.0 METs). Leptin at delivery correlated positively with body composition and negatively with light PA intensity. Sedentary behaviour showed a positive correlation with IL-6 levels at delivery. Moderate activity during the last trimester, sedentary activity levels, and body composition had the greatest influence on maternal IL-6 at delivery. Completed weeks of pregnancy, moderate and light PA, and sedentary activity had the greatest influence on maternal TNF-alpha at delivery. PA during late pregnancy potentially affects circulating (adipo-)/myokines. Further studies are needed to examine causal relationships and the impact on maternal and new-born health.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Bockler, Adeline UNSPECIFIED UNSPECIFIED UNSPECIFIED Ferrari, Nina UNSPECIFIED UNSPECIFIED UNSPECIFIED Deibert, Clara UNSPECIFIED UNSPECIFIED UNSPECIFIED Flock, Anne UNSPECIFIED UNSPECIFIED UNSPECIFIED Merz, Waltraut M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Gembruch, Ulrich UNSPECIFIED orcid.org/0000-0001-8284-4669 UNSPECIFIED Ehrhardt, Christina UNSPECIFIED UNSPECIFIED UNSPECIFIED Dotsch, Jorg UNSPECIFIED UNSPECIFIED UNSPECIFIED Joisten, Christine UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-588272
DOI:	10.3390/ijerph182413160
Journal or Publication Title:	Int. J. Environ. Res. Public Health
Volume:	18
Number:	24
Date:	2021
Publisher:	MDPI
Place of Publication:	BASEL
ISSN:	1660-4601
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language GESTATIONAL DIABETES-MELLITUS; SKELETAL-MUSCLE; SERUM INTERLEUKIN-6; LEPTIN; EXERCISE; MARKERS; HEALTH; WOMEN; RISK; GENE Multiple languages Environmental Sciences; Public, Environmental & Occupational Health Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/58827