Scherer, Simon ORCID: 0000-0002-6404-6919, Scheid, Christoph, von Bergwelt, Michael, Hellmich, Martin, Albus, Christian and Vitinius, Frank (2021). Psychosocial Pre-Transplant Screening With the Transplant Evaluation Rating Scale Contributes to Prediction of Survival After Hematopoietic Stem Cell Transplantation. Front. Psychiatry, 12. LAUSANNE: FRONTIERS MEDIA SA. ISSN 1664-0640

Full text not available from this repository.

Abstract

There is no standard in hematopoietic stem cell transplantations (HSCT) for pre-transplant screening of psychosocial risk factors, e.g., regarding immunosuppressant non-adherence. The aim of this prospective study is to explore the predictive value of the pretransplant psychosocial screening instrument Transplant Evaluation Rating Scale (TERS) for mortality in a 3-year follow-up. Between 2012 and 2017 61 patients were included and classified as low (TERS = 26.5-29) and increased-risk group (TERS = 29.5-79.5). Both groups were compared regarding mortality until 36 months after transplantation and secondary outcomes [Medication Experience Scale for Immunosuppressants (MESI); incidence/grade of GvHD]. The increased-risk group (n = 28) showed significantly worse cumulative survival in the outpatient setting (from 3 months to 3 years after HSCT) [Log Rank (Mantel Cox) P = 0.029] compared to low-risk group (n = 29) but there was no significant result for the interval immediately after HSCT until 3 years afterwards. Pre-transplant screening with TERS contributes to prediction of survival after HSCT. The reason remains unclear, since TERS did not correlate with GvHD or MESI. The negative result regarding the interval immediately after HSCT until 3 years could be caused by the intensive in-patient setting with mortality which is explained rather by biological reasons than by non-adherence.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Scherer, SimonUNSPECIFIEDorcid.org/0000-0002-6404-6919UNSPECIFIED
Scheid, ChristophUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
von Bergwelt, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hellmich, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Albus, ChristianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vitinius, FrankUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-588405
DOI: 10.3389/fpsyt.2021.741438
Journal or Publication Title: Front. Psychiatry
Volume: 12
Date: 2021
Publisher: FRONTIERS MEDIA SA
Place of Publication: LAUSANNE
ISSN: 1664-0640
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
MEDICATION ADHERENCE; COMORBIDITY INDEX; ORGAN TRANSPLANT; CANCER-PATIENTS; LEVELS SYSTEM; DEPRESSION; LEUKEMIA; MORBIDITY; DISEASE; ISSUESMultiple languages
PsychiatryMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/58840

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item