Universität zu Köln

Rutagarama, Florent, Muganga, Raymond, Konrad, Katja, Teteli, Raissa, Semakula, Muhammed, Musafili, Aimable, Laigong, Paul and Mutesa, Leon ORCID: 0000-0002-5308-3706 (2021). Vitamin D Levels in Mother-Baby Pairs: A Cross-Sectional Prospective Study in a Rwandan Tertiary Hospital. J. Trop. Pediatr., 67 (3). OXFORD: OXFORD UNIV PRESS. ISSN 1465-3664

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Abstract

Background: Exposure to the sunlight contributes largely to the production of vitamin D. However, vitamin D deficiency is a reality in tropical countries, despite enjoying enough sunlight, especially bearing women in their last trimester whose foetuses exclusively depend on their reserves. This work aimed at demonstrating the state of vitamin D in mother-baby pairs and associated factors in one of the University Hospitals in Rwanda. Methods: This cross-sectional prospective study was performed on mother-baby pairs at Kigali University Hospital. Mother's serum 25-hydroxyvitamin D levels were considered as outcomes compared with demographic, clinical and biological markers. Correlation analysis was conducted in order to assess the association between serum 25-hydroxyvitamin D levels for the couple mothers-babies. Results: Approximately 38% of women and 65% of neonates had deficiency in 25-hydroxyvitamin D (<20 ng/ml). The use of a vitamin D rich diet within 24 h recall (p < 0.01) or 1 week recall (p< 0.001) before delivery was associated with appropriate vitamin D levels in mothers. Interestingly, a strong positive correlation was found between maternal and neonatal serum 25-hydroxyvitamin D levels (r = 0.760). Conclusions: There was a high rate of vitamin D deficiency in mothers and their babies. Babies born from women with deficiency were likely to develop low levels of vitamin D. This stresses on the need to strengthen the interventions for preventing vitamin D deficiency in the couple mothers-babies such as supplement in vitamin D before and after delivery, improving the quality of meals and regular contact with sunlight.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Rutagarama, Florent UNSPECIFIED UNSPECIFIED UNSPECIFIED Muganga, Raymond UNSPECIFIED UNSPECIFIED UNSPECIFIED Konrad, Katja UNSPECIFIED UNSPECIFIED UNSPECIFIED Teteli, Raissa UNSPECIFIED UNSPECIFIED UNSPECIFIED Semakula, Muhammed UNSPECIFIED UNSPECIFIED UNSPECIFIED Musafili, Aimable UNSPECIFIED UNSPECIFIED UNSPECIFIED Laigong, Paul UNSPECIFIED UNSPECIFIED UNSPECIFIED Mutesa, Leon UNSPECIFIED orcid.org/0000-0002-5308-3706 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-589444
DOI:	10.1093/tropej/fmab024
Journal or Publication Title:	J. Trop. Pediatr.
Volume:	67
Number:	3
Date:	2021
Publisher:	OXFORD UNIV PRESS
Place of Publication:	OXFORD
ISSN:	1465-3664
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language D DEFICIENCY; PREVENTION Multiple languages Pediatrics; Tropical Medicine Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/58944