Universität zu Köln

Limper, Ulrich, Tank, Jens ORCID: 0000-0002-5672-1187, Ahnert, Tobias, Maegele, Marc, Grottke, Oliver ORCID: 0000-0002-0722-3122, Hein, Marc and Jordan, Jens (2021). The thrombotic risk of spaceflight: has a serious problem been overlooked for more than half of a century? Eur. Heart J., 42 (1). S. 97 - 102. OXFORD: OXFORD UNIV PRESS. ISSN 1522-9645

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Abstract

The first ever venous thrombotic condition associated with spaceflight, an internal jugular vein thrombus requiring anticoagulation, has recently been reported. Systematic investigation of space travel-associated thrombotic risk has not been conducted. Cellular, animal, and human studies performed in ground-based models and in actual weightlessness revealed influences of weightlessness and gravity on the blood coagulation system. However, human study populations were small and limited to highly selected participants. Evidence in individuals with medical conditions and older persons is lacking. Evidence for thrombotic risk in spaceflight is unsatisfactory. This issue deserves further study in heterogeneous, high risk populations to find prevention strategies and to enable safe governmental and touristic human spaceflight.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Limper, Ulrich UNSPECIFIED UNSPECIFIED UNSPECIFIED Tank, Jens UNSPECIFIED orcid.org/0000-0002-5672-1187 UNSPECIFIED Ahnert, Tobias UNSPECIFIED UNSPECIFIED UNSPECIFIED Maegele, Marc UNSPECIFIED UNSPECIFIED UNSPECIFIED Grottke, Oliver UNSPECIFIED orcid.org/0000-0002-0722-3122 UNSPECIFIED Hein, Marc UNSPECIFIED UNSPECIFIED UNSPECIFIED Jordan, Jens UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-591124
DOI:	10.1093/eurheartj/ehaa359
Journal or Publication Title:	Eur. Heart J.
Volume:	42
Number:	1
Page Range:	S. 97 - 102
Date:	2021
Publisher:	OXFORD UNIV PRESS
Place of Publication:	OXFORD
ISSN:	1522-9645
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language Cardiac & Cardiovascular Systems Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/59112