Kroeger, Jan Robert, Stackl, Marc, Weiss, Kilian 
ORCID: 0000-0003-4295-4585, Baessler, Bettina, Gerhardt, Felix, Rosenkranz, Stephan, Maintz, David, Giese, Daniel and Bunck, Alexander Christian
(2021).
k-t accelerated multi-VENC 4D flow MRI improves vortex assessment in pulmonary hypertension.
Eur. J. Radiol., 145.
CLARE:
ELSEVIER IRELAND LTD.
ISSN 1872-7727
Abstract
Background: 4D flow imaging can be used to evaluate vortex formation in the pulmonary artery seen in patients with pulmonary hypertension. We evaluated if a k-t accelerated multi-VENC (velocity encoding) 4D flow acquisition improves image quality, inter-reader agreement and correlation with hemodynamic parameters. Methods: A total of 14 patients with pulmonary hypertension (5 females, 9 males; mean age 61 +/- 16 years) underwent 4D flow MRI (magnetic resonance imaging) and right heart catheterization. In addition to that, 13 healthy volunteers (2 females, 11 males, mean age 33 +/- 12 years) also underwent 4D flow MRI. Multi- and single-VENC datasets were reconstructed and evaluated for vortex formation and vortex duration by two blinded readers and image quality was rated on a 5-point scale. Results: Both readers rated image quality as significantly higher on multi-VENC datasets (3.96 +/- 0.71 vs. 2.56 +/- 0.93, p < 0.001; 4.70 +/- 0.61 vs. 4.07 +/- 0.92, p = 0.003). Inter-reader correlation for vortex duration quantification was higher on multi-VENC datasets compared to single-VENC datasets (r = 0.63 vs. r = 0.44). No significant correlation was found between vortex duration and mean pulmonary artery pressure in patients with PH. Conclusion: Multi-VENC 4D flow MRI significantly improves image quality and inter-reader agreement for the evaluation of vortex formation in the pulmonary artery.
| Item Type: | Journal Article | ||||||||||||||||||||||||||||||||||||||||
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| URN: | urn:nbn:de:hbz:38-592485 | ||||||||||||||||||||||||||||||||||||||||
| DOI: | 10.1016/j.ejrad.2021.110035 | ||||||||||||||||||||||||||||||||||||||||
| Journal or Publication Title: | Eur. J. Radiol. | ||||||||||||||||||||||||||||||||||||||||
| Volume: | 145 | ||||||||||||||||||||||||||||||||||||||||
| Date: | 2021 | ||||||||||||||||||||||||||||||||||||||||
| Publisher: | ELSEVIER IRELAND LTD | ||||||||||||||||||||||||||||||||||||||||
| Place of Publication: | CLARE | ||||||||||||||||||||||||||||||||||||||||
| ISSN: | 1872-7727 | ||||||||||||||||||||||||||||||||||||||||
| Language: | English | ||||||||||||||||||||||||||||||||||||||||
| Faculty: | Unspecified | ||||||||||||||||||||||||||||||||||||||||
| Divisions: | Unspecified | ||||||||||||||||||||||||||||||||||||||||
| Subjects: | no entry | ||||||||||||||||||||||||||||||||||||||||
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| URI: | http://kups.ub.uni-koeln.de/id/eprint/59248 |
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