Universität zu Köln

Gupta, Amit ORCID: 0000-0001-5345-6763, Obmann, Verena Carola, Jordan, Michelle, Lennartz, Simon, Obmann, Markus Michael, Hokamp, Nils Grosse, Zopfs, David, Pennig, Lenhard, Fuertjes, Gina, Ramaiya, Nikhil, Gilkeson, Robert and Laukamp, Kai Roman (2021). CT artifacts after contrast media injection in chest imaging: evaluation of post-processing algorithms, virtual monoenergetic images and their combination for artifact reduction. Quant. Imaging Med. Surg., 11 (1). S. 226 - 240. SHATIN: AME PUBL CO. ISSN 2223-4306

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Abstract

Background: After injection into a brachial vein, high contrast media concentration in axillary and subclavian veins can cause artifacts that impair diagnostic utility. This study assessed artifact reduction by artifact-reduction-algorithms (ARA) and virtual-monoenergetic-images (VMI), as well as their combination (VMIARA) compared to conventional CT-images (CI). Methods: Forty-six spectral-detector-CT (SDCT) examinations of patients that received ARAreconstructions due to perivenous-artifacts were included in this retrospective study. CI, ARA, VMI, and VMIARA (range: 70-200 keV) were reconstructed. Objective analysis was performed with ROI-based assessment of mean and standard deviation of attenuation (HU) in hypoand hyperdense artifacts and impaired muscle and arteries as well as artifact-free reference-tissue. Extent of artifact reduction, assessment of surrounding soft tissue and vessels, and appearance of new artifacts were rated visually by two radiologists. Results: Hypoand hyperdense artifacts showed significant improvement as evidenced by decreasing attenuation differences between artifact impaired and artifact-free reference tissue in ARA, VMI 280 keV, and VMIARA between 70-200 keV (e.g., CI/ARA/VMI100keV/VMIARA100keV: hypodense artifacts, (-)264.8150.9/ (-)87.1 +/- 78.9/(-)48.6 +/- 64.6/9.9 +/- 63.9 HU; P<0.001); hyperdense artifacts, 164.2 +/- 51.1/82.1 +/- 73.2/7.9 +/- 34.7/ (-)17.3 +/- 50.7 HU; P<0.001). Artifacts impairing surrounding muscle and arteries were also reduced by all three approaches. In visual assessment, ARA, VMI 2100 keV, and VMIARA between 70-200 keV also showed significant artifact reduction and improved assessment; however, for assessment of arteries improvement was not significant using ARA alone. New artifacts were reported, particularly at higher keV-values. Conclusions: In presence of perivenous-artifacts, ARA, VMI and their combination allow for significant artifact reduction; however, their combination and VMI as a standalone approach yielded best results and should therefore be used, if available.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Gupta, Amit UNSPECIFIED orcid.org/0000-0001-5345-6763 UNSPECIFIED Obmann, Verena Carola UNSPECIFIED UNSPECIFIED UNSPECIFIED Jordan, Michelle UNSPECIFIED UNSPECIFIED UNSPECIFIED Lennartz, Simon UNSPECIFIED UNSPECIFIED UNSPECIFIED Obmann, Markus Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Hokamp, Nils Grosse UNSPECIFIED UNSPECIFIED UNSPECIFIED Zopfs, David UNSPECIFIED UNSPECIFIED UNSPECIFIED Pennig, Lenhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Fuertjes, Gina UNSPECIFIED UNSPECIFIED UNSPECIFIED Ramaiya, Nikhil UNSPECIFIED UNSPECIFIED UNSPECIFIED Gilkeson, Robert UNSPECIFIED UNSPECIFIED UNSPECIFIED Laukamp, Kai Roman UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-593915
DOI:	10.21037/qims-20-435
Journal or Publication Title:	Quant. Imaging Med. Surg.
Volume:	11
Number:	1
Page Range:	S. 226 - 240
Date:	2021
Publisher:	AME PUBL CO
Place of Publication:	SHATIN
ISSN:	2223-4306
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language DUAL-ENERGY CT; DETECTOR-ROW CT; MONOCHROMATIC IMAGES; COMPUTED-TOMOGRAPHY; SALINE FLUSH; SPECTRAL CT; RECONSTRUCTIONS; EXTRAPOLATIONS; COEFFICIENT; PRINCIPLES Multiple languages Radiology, Nuclear Medicine & Medical Imaging Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/59391