Universität zu Köln

Haidl, Theresa Katharina, Gruen, Michael, Dizinger, Julian ORCID: 0000-0001-7934-8082, Rosen, Marlene, Doll, Carolin Martha, Penzel, Nora ORCID: 0000-0003-1624-386X, Daum, Lukas, Hokamp, Nils Grosse, Klosterkotter, Joachim, Ruhrmann, Stephan, Vogeley, Kai ORCID: 0000-0002-5891-5831, Schultze-Lutter, Frauke and Kambeitz, Joseph ORCID: 0000-0002-8988-3959 (2021). Is there a diagnosis-specific influence of childhood trauma on later educational attainment? A machine learning analysis in a large help-seeking sample. J. Psychiatr. Res., 138. S. 591 - 598. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. ISSN 1879-1379

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Abstract

Background: Childhood adversities and trauma (CAT) are associated with poor functional outcome. However, the influence of the single CAT aspects on the risk of a poor functional outcome within different mental disorders has not been investigated so far. Our aims were (i) to predict individual functional outcome based on CAT (ii) to examine whether the prediction power differs within different diagnostic groups (clinical high-risk for psychosis (CHR), psychosis, affective disorders, anxiety disorders) (iii) to compare the specific patterns of CAT experiences, influencing functional outcomes in these groups. Method: Clinical data of 707 patients (mean age: 25.09 years (SD = 5.6), 65.5% male) of the Cologne Early Recognition and Intervention Center were assessed with the Trauma And Distress Scale. Functional outcome was estimated by the Social and Occupational Functioning Assessment Scale and school educational attainment. Using machine learning, we generated individualized models to predict functional outcome and to identify specific CAT patterns. Results: Across the entire sample, the best prediction for the functional outcome achieved a balanced accuracy (BAC) of 0.6. After splitting into the single diagnostic groups, an improvement with best results in the psychosis group (BAC = 0.70) was observed. Considering specific CAT patterns, the most predictive items depicted a positive and caring environment-or the absence of these, a positive self-image and experiences of bullying. Conclusions: Our results indicated that CAT was differentially associated with functional outcome in the various mental disorders. Thus, the importance of mediating variables, that might explain the interindividual differences in the vulnerability to CAT, like resilience factors, appeared to be crucial.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Haidl, Theresa Katharina UNSPECIFIED UNSPECIFIED UNSPECIFIED Gruen, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Dizinger, Julian UNSPECIFIED orcid.org/0000-0001-7934-8082 UNSPECIFIED Rosen, Marlene UNSPECIFIED UNSPECIFIED UNSPECIFIED Doll, Carolin Martha UNSPECIFIED UNSPECIFIED UNSPECIFIED Penzel, Nora UNSPECIFIED orcid.org/0000-0003-1624-386X UNSPECIFIED Daum, Lukas UNSPECIFIED UNSPECIFIED UNSPECIFIED Hokamp, Nils Grosse UNSPECIFIED UNSPECIFIED UNSPECIFIED Klosterkotter, Joachim UNSPECIFIED UNSPECIFIED UNSPECIFIED Ruhrmann, Stephan UNSPECIFIED UNSPECIFIED UNSPECIFIED Vogeley, Kai UNSPECIFIED orcid.org/0000-0002-5891-5831 UNSPECIFIED Schultze-Lutter, Frauke UNSPECIFIED UNSPECIFIED UNSPECIFIED Kambeitz, Joseph UNSPECIFIED orcid.org/0000-0002-8988-3959 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-594848
DOI:	10.1016/j.jpsychires.2021.04.040
Journal or Publication Title:	J. Psychiatr. Res.
Volume:	138
Page Range:	S. 591 - 598
Date:	2021
Publisher:	PERGAMON-ELSEVIER SCIENCE LTD
Place of Publication:	OXFORD
ISSN:	1879-1379
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PSYCHIATRIC-DISORDERS; FUNCTIONAL OUTCOMES; MENTAL-HEALTH; RISK; PSYCHOSIS; MALTREATMENT; RESILIENCE; DEPRESSION; ABUSE; PSYCHOPATHOLOGY Multiple languages Psychiatry Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/59484