Universität zu Köln

Classen, Annika Y., Henze, Larissa, Von Lilienfeld-Toal, Marie, Maschmeyer, Georg, Sandherr, Michael, Graeff, Luisa Duran, Alakel, Nael, Christopeit, Maximilian, Krause, Stefan W., Mayer, Karin, Neumann, Silke, Cornely, Oliver A., Penack, Olaf ORCID: 0000-0003-4876-802X, Weissinger, Florian, Wolf, Hans-Heinrich and Vehreschild, Joerg Janne (2021). Primary prophylaxis of bacterial infections and Pneumocystis jirovecii pneumonia in patients with hematologic malignancies and solid tumors: 2020 updated guidelines of the Infectious Diseases Working Party of the German Society of Hematology and Medical Oncology (AGIHO/DGHO). Ann. Hematol., 100 (6). S. 1603 - 1621. NEW YORK: SPRINGER. ISSN 1432-0584

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Abstract

Hematologic and oncologic patients with chemo- or immunotherapy-related immunosuppression are at substantial risk for bacterial infections and Pneumocystis jirovecii pneumonia (PcP). As bacterial resistances are increasing worldwide and new research reshapes our understanding of the interactions between the human host and bacterial commensals, administration of antibacterial prophylaxis has become a matter of discussion. This guideline constitutes an update of the 2013 published guideline of the Infectious Diseases Working Party (AGIHO) of the German Society for Hematology and Medical Oncology (DGHO). It gives an overview about current strategies for antibacterial prophylaxis in cancer patients while taking into account the impact of antibacterial prophylaxis on the human microbiome and resistance development. Current literature published from January 2012 to August 2020 was searched and evidence-based recommendations were developed by an expert panel. All recommendations were discussed and approved in a consensus conference of the AGIHO prior to publication. As a result, we present a comprehensive update and extension of our guideline for antibacterial and PcP prophylaxis in cancer patients.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Classen, Annika Y. UNSPECIFIED UNSPECIFIED UNSPECIFIED Henze, Larissa UNSPECIFIED UNSPECIFIED UNSPECIFIED Von Lilienfeld-Toal, Marie UNSPECIFIED UNSPECIFIED UNSPECIFIED Maschmeyer, Georg UNSPECIFIED UNSPECIFIED UNSPECIFIED Sandherr, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Graeff, Luisa Duran UNSPECIFIED UNSPECIFIED UNSPECIFIED Alakel, Nael UNSPECIFIED UNSPECIFIED UNSPECIFIED Christopeit, Maximilian UNSPECIFIED UNSPECIFIED UNSPECIFIED Krause, Stefan W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Mayer, Karin UNSPECIFIED UNSPECIFIED UNSPECIFIED Neumann, Silke UNSPECIFIED UNSPECIFIED UNSPECIFIED Cornely, Oliver A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Penack, Olaf UNSPECIFIED orcid.org/0000-0003-4876-802X UNSPECIFIED Weissinger, Florian UNSPECIFIED UNSPECIFIED UNSPECIFIED Wolf, Hans-Heinrich UNSPECIFIED UNSPECIFIED UNSPECIFIED Vehreschild, Joerg Janne UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-603485
DOI:	10.1007/s00277-021-04452-9
Journal or Publication Title:	Ann. Hematol.
Volume:	100
Number:	6
Page Range:	S. 1603 - 1621
Date:	2021
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1432-0584
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language STEM-CELL TRANSPLANTATION; BLOOD-STREAM INFECTIONS; LACTAMASE-PRODUCING ENTEROBACTERIACEAE; CLOSTRIDIUM-DIFFICILE INFECTION; FEBRILE NEUTROPENIC PATIENTS; ACUTE-LEUKEMIA PATIENTS; ACUTE MYELOID-LEUKEMIA; HIGH-RISK PATIENTS; CARINII-PNEUMONIA; TRIMETHOPRIM-SULFAMETHOXAZOLE Multiple languages Hematology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/60348