Universität zu Köln

Yagdiran, Ayla ORCID: 0000-0002-1723-5995, Meyer-Schwickerath, Charlotte ORCID: 0000-0001-6711-6516, Wolpers, Raphael, Otto-Lambertz, Christina ORCID: 0000-0003-4083-7078, Mehler, Katrin ORCID: 0000-0002-3052-2147, Oberthuer, Andre, Kernich, Nikolaus, Eysel, Peer, Jung, Norma ORCID: 0000-0002-5740-0772 and Zarghooni, Kourosh ORCID: 0000-0001-7069-6291 (2022). What Do We Know about Spondylodiscitis in Children? A Retrospective Study. Children-Basel, 9 (8). BASEL: MDPI. ISSN 2227-9067

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Abstract

Pediatric spondylodiscitis (PSD) is a rare disease with a major impact on mobility and functional status. Data concerning demographic and microbiological characteristics, clinical course, treatment, and outcome are scarce. Therefore, the aim of this study was to present clinical experiences of a third-level hospital (2009-2019) in PSD and compare these with adult spondylodiscitis (ASD). Of a total of 10 PSD patients, most of the infants presented with unspecific pain such as hip pain or a limping, misleading an adequate diagnosis of spine origin. Eight patients could be treated conservatively whereas surgery was performed in two cases with one case of tuberculous PSD (tPSD). The causative agent was detected in three of the patients. The diagnosis of PSD is often difficult since clinical symptoms are unspecific and causative pathogens often remain undetected. Nevertheless, empirical anti-infective therapy also seems to be effective. Based on recent studies, clinicians should be encouraged to keep the duration of anti-infective therapy in children short. Since comorbidities are not presented in PSD it is unclear which children suffer from PSD; thus, studies are necessary to identify predisposing factors for PSD. In our study, PSD differs from ASD in diagnostic and especially in therapeutic aspects. Therefore, specific guidelines for PSD would be desirable.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Yagdiran, Ayla UNSPECIFIED orcid.org/0000-0002-1723-5995 UNSPECIFIED Meyer-Schwickerath, Charlotte UNSPECIFIED orcid.org/0000-0001-6711-6516 UNSPECIFIED Wolpers, Raphael UNSPECIFIED UNSPECIFIED UNSPECIFIED Otto-Lambertz, Christina UNSPECIFIED orcid.org/0000-0003-4083-7078 UNSPECIFIED Mehler, Katrin UNSPECIFIED orcid.org/0000-0002-3052-2147 UNSPECIFIED Oberthuer, Andre UNSPECIFIED UNSPECIFIED UNSPECIFIED Kernich, Nikolaus UNSPECIFIED UNSPECIFIED UNSPECIFIED Eysel, Peer UNSPECIFIED UNSPECIFIED UNSPECIFIED Jung, Norma UNSPECIFIED orcid.org/0000-0002-5740-0772 UNSPECIFIED Zarghooni, Kourosh UNSPECIFIED orcid.org/0000-0001-7069-6291 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-658340
DOI:	10.3390/children9081103
Journal or Publication Title:	Children-Basel
Volume:	9
Number:	8
Date:	2022
Publisher:	MDPI
Place of Publication:	BASEL
ISSN:	2227-9067
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language INFECTIONS; PAIN Multiple languages Pediatrics Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/65834