Universität zu Köln

Lehmann, Helmar C. (2022). Neuromuscular manifestations in long-COVID syndrome. Nervenarzt, 93 (8). S. 761 - 769. NEW YORK: SPRINGER. ISSN 1433-0407

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Abstract

The term long-COVID syndrome encompasses symptoms that occur after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, persisting over a period of several weeks, and which cannot be explained by another diagnosis. Long-COVID is considered to be a multiorgan condition. In this review article, the data regarding neuromuscular manifestations of long-COVID syndrome are summarized and evaluated based on criteria, such as effect size, plausibility, coherence, and experimental evidence. So far, myalgia and autonomic dysfunction (especially postural tachycardia syndrome) have been postulated as neuromuscular symptoms of long-COVID; however, the evidence to date is limited. In addition to very heterogeneous methodologies and different definitions of long-COVID in the clinical studies, conclusive experimental data supporting the described symptoms as a specific long-term consequence of COVID-19 are lacking.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Lehmann, Helmar C. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-660748
DOI:	10.1007/s00115-022-01321-2
Journal or Publication Title:	Nervenarzt
Volume:	93
Number:	8
Page Range:	S. 761 - 769
Date:	2022
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1433-0407
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MUSCULOSKELETAL PAIN; MUSCLE BIOPSY; CONSEQUENCES; TACHYCARDIA; FATIGUE; DISEASE Multiple languages Clinical Neurology; Psychiatry Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/66074