Universität zu Köln

Nachtsheim, Lisa, Prinz, Johanna, Arolt, Christoph, Quaas, Alexander, Meyer, Moritz, Klussmann, Jens Peter and Wolber, Philipp (2022). Novel therapeutic approaches for salivary gland carcinomas. Laryngo-Rhino-Otol., 101 (11). S. 876 - 882. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1438-8685

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Abstract

Novel therapeutic options for the treatment of salivary gland malignancies have emerged due to the improvement and distribution of molecular pathological testing methods and the availability of targeted therapies. Since they are less toxic, these new agents are a valuable alternative to conventional cytotoxic chemotherapy. On the one hand, there are new entity-specific therapies such as NTRK inhibitor therapy for secretory carcinomas and axitinib therapy for adenoid cystic carcinomas. Moreover, cross-entity therapeutics such as antiandrogenic therapy, HER2 inhibition, and PI3K inhibition are also coming to the fore. For metastatic/recurrent salivary gland carcinomas that cannot be treated with targeted therapy, platinum-based chemotherapies continue to be therapy of choice.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Nachtsheim, Lisa UNSPECIFIED UNSPECIFIED UNSPECIFIED Prinz, Johanna UNSPECIFIED UNSPECIFIED UNSPECIFIED Arolt, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED Quaas, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Meyer, Moritz UNSPECIFIED UNSPECIFIED UNSPECIFIED Klussmann, Jens Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Wolber, Philipp UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-665988
DOI:	10.1055/a-1792-2246
Journal or Publication Title:	Laryngo-Rhino-Otol.
Volume:	101
Number:	11
Page Range:	S. 876 - 882
Date:	2022
Publisher:	GEORG THIEME VERLAG KG
Place of Publication:	STUTTGART
ISSN:	1438-8685
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language POSITIVE SOLID TUMORS; PHASE-II; CYCLOPHOSPHAMIDE; DOXORUBICIN; CISPLATIN; CLASSIFICATION; CHEMOTHERAPY; PROGNOSIS; CANCER Multiple languages Otorhinolaryngology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/66598