Fischer, Anne Kristin, Schoemig-Markiefka, Birgid, Heydt, Carina, Ratiu, Dominik, Mallmann, Peter, Meinel, Jorn, Buettner, Reinhard, Schmidt, Dietmar and Quaas, Alexander . Incidental FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci. Virchows Arch.. NEW YORK: SPRINGER. ISSN 1432-2307

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Abstract

We report on the incidental finding of a FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci, a rare entity recently described by Jennifer N. Stall and Robert H. Young in a series of sixteen cases in 2019, displaying features differing from conventional adult granulosa cell tumour. Our aim is to specify the morphologic and molecular particularities of this presumably underrecognized finding, with a short presentation of the typical clinical context. Awareness of this rare and challenging neoplasm with indeterminate clinical course is crucial in routine diagnostics.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Fischer, Anne KristinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schoemig-Markiefka, BirgidUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Heydt, CarinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ratiu, DominikUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mallmann, PeterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Meinel, JornUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Buettner, ReinhardUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schmidt, DietmarUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Quaas, AlexanderUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-667381
DOI: 10.1007/s00428-022-03452-y
Journal or Publication Title: Virchows Arch.
Publisher: SPRINGER
Place of Publication: NEW YORK
ISSN: 1432-2307
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
TERM-FOLLOW-UP; PROGNOSTIC-FACTORS; BEVACIZUMAB; RECURRENCE; SURVIVAL; GATA-4; EGFR; HER2Multiple languages
PathologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/66738

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