Universität zu Köln

Niehoff, Julius Henning, Carmichael, Alexandra Fiona, Woeltjen, Matthias Michael ORCID: 0000-0001-7624-5109, Boriesosdick, Jan, Schmidt, Ingo Lopez, Michael, Arwed Elias, Hokamp, Nils Grosse, Piechota, Hansjuergen, Borggrefe, Jan ORCID: 0000-0003-2908-7560 and Kroeger, Jan Robert ORCID: 0000-0003-1218-7610 (2022). Clinical Low Dose Photon Counting CT for the Detection of Urolithiasis: Evaluation of Image Quality and Radiation Dose. Tomography, 8 (4). S. 1666 - 1676. BASEL: MDPI. ISSN 2379-139X

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Abstract

The purpose of this study was the evaluation of image quality and radiation dose parameters of the novel photon counting CT (PCCT, Naeotom Alpha, Siemens Healthineers) using low-dose scan protocols for the detection of urolithiasis. Standard CT scans were used as a reference (S40, Somatom Sensation 40, Siemens Healthineers). Sixty-three patients, who underwent CT scans between August and December 2021, were retrospectively enrolled. Thirty-one patients were examined with the PCCT and 32 patients were examined with the S40. Radiation dose parameters, as well as quantitative and qualitative image parameters, were analyzed. The presence of urolithiasis, image quality, and diagnostic certainty were rated on a 5-point-scale by 3 blinded readers. Both patient groups (PCCT and S40) did not differ significantly in terms of body mass index. Radiation dose was significantly lower for examinations with the PCCT compared to the S40 (2.4 +/- 1.0 mSv vs. 3.4 +/- 1.0 mSv; p < 0.001). The SNR was significantly better on images acquired with the PCCT (13.3 +/- 3.3 vs. 8.2 +/- 1.9; p < 0.001). The image quality of the PCCT was rated significantly better (4.3 +/- 0.7 vs. 2.8 +/- 0.6; p < 0.001). The detection rate of kidney or ureter calculi was excellent with both CT scanners (PCCT 97.8% and S40 99%, p = 0.611). In high contrast imaging, such as the depiction of stones of the kidney and the ureter, PCCT allows a significant reduction of radiation dose, while maintaining excellent diagnostic confidence and image quality. Given this image quality with our current protocol, further adjustments towards ultra-low-dose CT scans appear feasible.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Niehoff, Julius Henning UNSPECIFIED UNSPECIFIED UNSPECIFIED Carmichael, Alexandra Fiona UNSPECIFIED UNSPECIFIED UNSPECIFIED Woeltjen, Matthias Michael UNSPECIFIED orcid.org/0000-0001-7624-5109 UNSPECIFIED Boriesosdick, Jan UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmidt, Ingo Lopez UNSPECIFIED UNSPECIFIED UNSPECIFIED Michael, Arwed Elias UNSPECIFIED UNSPECIFIED UNSPECIFIED Hokamp, Nils Grosse UNSPECIFIED UNSPECIFIED UNSPECIFIED Piechota, Hansjuergen UNSPECIFIED UNSPECIFIED UNSPECIFIED Borggrefe, Jan UNSPECIFIED orcid.org/0000-0003-2908-7560 UNSPECIFIED Kroeger, Jan Robert UNSPECIFIED orcid.org/0000-0003-1218-7610 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-668688
DOI:	10.3390/tomography8040138
Journal or Publication Title:	Tomography
Volume:	8
Number:	4
Page Range:	S. 1666 - 1676
Date:	2022
Publisher:	MDPI
Place of Publication:	BASEL
ISSN:	2379-139X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language KIDNEY-STONES; MAMMOGRAPHY Multiple languages Radiology, Nuclear Medicine & Medical Imaging Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/66868