Universität zu Köln

Grunz, Jan-Peter ORCID: 0000-0002-4524-1620, Heidenreich, Julius Frederik, Lennartz, Simon, Weighardt, Jens Philipp, Bley, Thorsten Alexander, Erguen, Sueleyman, Petritsch, Bernhard and Huflage, Henner ORCID: 0000-0002-2784-3257 (2022). Spectral Shaping Via Tin Prefiltration in Ultra-High-Resolution Photon-Counting and Energy-Integrating Detector CT of the Temporal Bone. Invest. Radiol., 57 (12). S. 819 - 826. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1536-0210

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Abstract

ObjectivesHardening the x-ray beam, tin prefiltration is established for imaging of high-contrast subjects in energy-integrating detector computed tomography (EID-CT). With this work, we aimed to investigate the dose-saving potential of spectral shaping via tin prefiltration in photon-counting detector CT (PCD-CT) of the temporal bone.MethodsDeploying dose-matched scan protocols with and without tin prefiltration on a PCD-CT and EID-CT system (low-/intermediate-/full-dose: 4.8/7.6-7.7/27.0-27.1 mGy), 12 ultra-high-resolution examinations were performed on each of 5 cadaveric heads. While 120 kVp was applied for standard imaging, the protocols with spectral shaping used the highest potential available with tin prefiltration (EID-CT: Sn 150 kVp, PCD-CT: Sn 140 kVp). Contrast-to-noise ratios and dose-saving potential by spectral shaping were computed for each scanner. Three radiologists independently assessed the image quality of each examination with the intraclass correlation coefficient being computed to measure interrater agreement.ResultsRegardless of tin prefiltration, PCD-CT with low (171.2 +/- 10.3 HU) and intermediate radiation dose (134.7 +/- 4.5 HU) provided less image noise than full-dose EID-CT (177.0 +/- 14.2 HU; P < 0.001). Targeting matched image noise to 120 kVp EID-CT, mean dose reduction of 79.3% +/- 3.9% could be realized in 120 kVp PCD-CT. Subjective image quality of PCD-CT was better than of EID-CT on each dose level (P < 0.050). While no distinction was found between dose-matched PCD-CT with and without tin prefiltration (P >= 0.928), Sn 150 kVp EID-CT provided better image quality than 120 kVp EID-CT at high and intermediate dose levels (P > 0.050). The majority of low-dose EID-CT examinations were considered not diagnostic, whereas PCD-CT scans of the same dose level received satisfactory or better ratings. Interrater reliability was excellent (intraclass correlation coefficient 0.903).ConclusionsPCD-CT provides superior image quality and significant dose savings compared with EID-CT for ultra-high-resolution examinations of the temporal bone. Aiming for matched image noise, high-voltage scan protocols with tin prefiltration facilitate additional dose saving in EID-CT, whereas superior inherent denoising decreases the dose reduction potential of spectral shaping in PCD-CT.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Grunz, Jan-Peter UNSPECIFIED orcid.org/0000-0002-4524-1620 UNSPECIFIED Heidenreich, Julius Frederik UNSPECIFIED UNSPECIFIED UNSPECIFIED Lennartz, Simon UNSPECIFIED UNSPECIFIED UNSPECIFIED Weighardt, Jens Philipp UNSPECIFIED UNSPECIFIED UNSPECIFIED Bley, Thorsten Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Erguen, Sueleyman UNSPECIFIED UNSPECIFIED UNSPECIFIED Petritsch, Bernhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Huflage, Henner UNSPECIFIED orcid.org/0000-0002-2784-3257 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-669960
DOI:	10.1097/RLI.0000000000000901
Journal or Publication Title:	Invest. Radiol.
Volume:	57
Number:	12
Page Range:	S. 819 - 826
Date:	2022
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1536-0210
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language COMPUTED-TOMOGRAPHY; IMAGE QUALITY; OPTIMIZATION; CHILDREN; FILTER Multiple languages Radiology, Nuclear Medicine & Medical Imaging Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/66996