Universität zu Köln

Li, Xueting, Li, Senmao, Fan, Wanlin, Rokohl, Alexander C., Ju, Sitong, Ju, Xiaojun, Guo, Yongwei ORCID: 0000-0001-9195-0770 and Heindl, Ludwig M. (2023). Recent advances in graves ophthalmopathy medical therapy: a comprehensive literature review. Int. Ophthalmol., 43 (4). S. 1437 - 1450. DORDRECHT: SPRINGER. ISSN 1573-2630

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Abstract

Graves ophthalmopathy (GO), which occurs in autoimmune thyroid disease, can reduce patients' quality of life due to its impact on visual function, physical appearance, and emotional health. Corticosteroids have been the first-line treatment for GO. More recently, the pathogenesis of GO has made significant progress. Various targeting biological agents and immunosuppressive agents make GO management more promising. Fully understanding GO pathogenesis and precise clinical management are beneficial for the prognosis of patients. Therefore, we conducted a comprehensive review of the medical management of GO and summarized research developments to highlight future research issues.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Li, Xueting UNSPECIFIED UNSPECIFIED UNSPECIFIED Li, Senmao UNSPECIFIED UNSPECIFIED UNSPECIFIED Fan, Wanlin UNSPECIFIED UNSPECIFIED UNSPECIFIED Rokohl, Alexander C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Ju, Sitong UNSPECIFIED UNSPECIFIED UNSPECIFIED Ju, Xiaojun UNSPECIFIED UNSPECIFIED UNSPECIFIED Guo, Yongwei UNSPECIFIED orcid.org/0000-0001-9195-0770 UNSPECIFIED Heindl, Ludwig M. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-670691
DOI:	10.1007/s10792-022-02537-6
Journal or Publication Title:	Int. Ophthalmol.
Volume:	43
Number:	4
Page Range:	S. 1437 - 1450
Date:	2023
Publisher:	SPRINGER
Place of Publication:	DORDRECHT
ISSN:	1573-2630
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language THYROID EYE DISEASE; MYCOPHENOLATE-MOFETIL; ORBITAL FIBROBLASTS; COMBINED IMMUNOSUPPRESSION; NATURAL-HISTORY; ACTIVE MODERATE; EUROPEAN GROUP; ORBITOPATHY; TEPROTUMUMAB; RITUXIMAB Multiple languages Ophthalmology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/67069