Universität zu Köln

Kiessling, D., Rennings, C., Hild, M., Lappas, A., Dietlein, T. S., Roessler, G. F. and Widder, R. A. (2022). Predictability of success and open conjunctival revision rates in the subsequent eye after XEN45 Gel Stent implantation according to lens status. Graefes Arch. Clin. Exp. Ophthalmol., 260 (8). S. 2639 - 2648. NEW YORK: SPRINGER. ISSN 1435-702X

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Abstract

Purpose To determine the predictability of success and the risk of open conjunctival revision in the subsequent eye after XEN45 Gel Stent implantation according to lens status. Methods This was a retrospective single-centre study involving 132 eyes of 66 participants who had undergone intraocular pressure (IOP)-lowering XEN45 Gel Stent implantation, either as a standalone procedure in phakic and pseudophakic eyes or in combination with phacoemulsification. Successful surgery was defined by three scores: IOP at follow-up < 21 mmHg (score A) or < 18 mmHg (score B) and an IOP reduction > 20% or IOP <= 15 mmHg and an IOP reduction >= 40% (score C). In all scores, one open conjunctival revision was allowed, and additional repeat surgery was considered a failure. The predictability of success and revision rate depending on the outcome of the first eye were calculated using Bayes' theorem. Results IOP-lowering did not differ significantly between the first and second eyes. Success rates of standalone surgery in the second eye after successful surgery in the first eye significantly exceed rates after prior failure. For the combined procedure, the rates did not differ significantly. For score A, we determined a 76.6% chance of success following a prior success and a 57.9% chance, if prior surgery failed. The corresponding probabilities were 75% and 59.1% for score B, while 66.7% and 15.7% for score C, respectively. We calculated a 60% risk for revision surgery in the standalone phakic group. If the first eye was not revised, the risk of revision in the subsequent eye was 20%. The corresponding risks were 72.7% and 5% for the standalone procedure in pseudophakic patients and 38.4% and 41.7% for the combined procedure, respectively. Conclusion The results of our study offer a tool to predict the outcome of subsequent eye surgeries based on either the outcome in the initial eye and the type of surgery performed, owing to the high predictive potential.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kiessling, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Rennings, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hild, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Lappas, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Dietlein, T. S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Roessler, G. F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Widder, R. A. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-671003
DOI:	10.1007/s00417-022-05569-x
Journal or Publication Title:	Graefes Arch. Clin. Exp. Ophthalmol.
Volume:	260
Number:	8
Page Range:	S. 2639 - 2648
Date:	2022
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1435-702X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language RISK-FACTORS; GLAUCOMA; TRABECULECTOMY; CATARACT; SURGERY; FAILURE Multiple languages Ophthalmology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/67100