Universität zu Köln

Celik, Erkan ORCID: 0000-0001-5687-7707, Goertz, Lukas, Nelles, Christian, Hammes, Jochen, Achenbach, Tobias, Kabbasch, Christoph, Persigehl, Thorsten, Maintz, David and Bunck, Alexander Christian (2022). The Aortic Ductus Diverticulum-Innocent Bystander or Potential Source of Thromboembolic Stroke? J. Comput. Assist. Tomogr., 46 (3). S. 392 - 397. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1532-3145

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Abstract

Objective Due to reversal blood flow in the diastolic phase, outpouchings at the aortic isthmus may carry the risk of thrombus formation and subsequent thromboembolism. The objective was to evaluate the association between aortic ductus diverticula (ADDs) and ischemic brain alterations in cerebral magnetic resonance imaging. Methods A retrospective analysis of 218 patients who received both a dedicated computed tomography angiography of the thoracic aorta and a brain magnetic resonance imaging was performed. Two radiologists independently reviewed all examinations for the presence of ADD as well as ischemic alterations of the brain. The association between this anatomical variant and ischemic brain alterations was evaluated by univariate and bivariate logistic regression analyses. Results ADDs were identified/present in 35 of 218 patients (16%). Ischemic brain alterations were found in 57% of patients (20/35) with an ADD and in 42% of the control group (77/183, P = 0.1). The presence of an ADD did not prove to be an independent risk factor for ischemic brain alterations after multivariate adjustment (odds ratio = 1.7, 95% confidence interval = 0.72-3.96, P = 0.225). Conclusions In the present study, ADDs were not significantly associated with ischemic brain alterations. Therefore, ADDs seem to be an innocent bystander with respect to the pathogenesis of ischemic brain alterations.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Celik, Erkan UNSPECIFIED orcid.org/0000-0001-5687-7707 UNSPECIFIED Goertz, Lukas UNSPECIFIED UNSPECIFIED UNSPECIFIED Nelles, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Hammes, Jochen UNSPECIFIED UNSPECIFIED UNSPECIFIED Achenbach, Tobias UNSPECIFIED UNSPECIFIED UNSPECIFIED Kabbasch, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED Persigehl, Thorsten UNSPECIFIED UNSPECIFIED UNSPECIFIED Maintz, David UNSPECIFIED UNSPECIFIED UNSPECIFIED Bunck, Alexander Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-673587
DOI:	10.1097/RCT.0000000000001287
Journal or Publication Title:	J. Comput. Assist. Tomogr.
Volume:	46
Number:	3
Page Range:	S. 392 - 397
Date:	2022
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1532-3145
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ATRIAL SEPTAL POUCH; RETROGRADE EMBOLIZATION; RISK-FACTOR Multiple languages Radiology, Nuclear Medicine & Medical Imaging Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/67358