Universität zu Köln

Scheurlen, Cornelia ORCID: 0000-0001-7054-3535, van den Bruck, Jan-Hendrik, Filipovic, Karlo, Woermann, Jonas, Arica, Zeynep, Erlhoefer, Susanne, Dittrich, Sebastian, Heijman, Jordi ORCID: 0000-0002-1418-108X, Lueker, Jakob, Steven, Daniel and Sultan, Arian ORCID: 0000-0003-1807-4860 (2022). Procedural and outcome impact of obesity in cryoballoon versus radiofrequency pulmonary vein isolation in atrial fibrillation patients. J. Interv. Card. Electrophysiol., 65 (2). S. 403 - 411. DORDRECHT: SPRINGER. ISSN 1572-8595

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Abstract

Purpose Cryoballoon (CB) ablation and radiofrequency (RF) ablation are the most common techniques for pulmonary vein isolation (PVI) in patients with symptomatic atrial fibrillation (AF). An increasing number of patients undergoing PVI are obese. To address the paucity of data on outcomes of CB- vs. RF-based PVI in relation to body mass index (BMI) of AF patients. Methods All patients undergoing de novo PVI between 01/2018 and 08/2019 at University Hospital Cologne were included in this retrospective analysis. Patients of each group (CB-PVI vs. RF-PVI) were analyzed based on their BMI. Hereafter, procedural characteristics and AF recurrence rate were compared regarding different BMI groups. Results A total of 526 patients (62% male, 65 +/- 11 years) underwent successful de novo PVI (320 CB and 206 RF). In obese patients, two differences in procedural characteristics were noted: A significantly increased contrast medium volume in CB group and a lower fluoroscopy dose in RF group: contrast medium: CB 50 [40-80] vs. RF 20 [20-30], p<0.001; fluoroscopy dose: CB 392.4 [197.9-995.9] vs. RF 282.5 [139.8-507.2], p<0.001. The complication rate was equal throughout all BMI groups, regardless of CB or RF usage. For obese patients, a trend toward a higher AF recurrence rate was revealed after RF-PVI as compared to CB-PVI. In line with previous studies, the overall procedure time was significantly shorter with CB-PVI regardless of BMI. Conclusion For obese patients, CB-PVI is similarly safe and effective as RF-PVI. The significantly shorter procedure time for CB-PVI may minimize potential obesity-related complications. However, the lower contrast medium quantity and fluoroscopy dose in RF-PVI must be considered. AF recurrence rates were comparable between CB-PVI and RF-PVI.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Scheurlen, Cornelia UNSPECIFIED orcid.org/0000-0001-7054-3535 UNSPECIFIED van den Bruck, Jan-Hendrik UNSPECIFIED UNSPECIFIED UNSPECIFIED Filipovic, Karlo UNSPECIFIED UNSPECIFIED UNSPECIFIED Woermann, Jonas UNSPECIFIED UNSPECIFIED UNSPECIFIED Arica, Zeynep UNSPECIFIED UNSPECIFIED UNSPECIFIED Erlhoefer, Susanne UNSPECIFIED UNSPECIFIED UNSPECIFIED Dittrich, Sebastian UNSPECIFIED UNSPECIFIED UNSPECIFIED Heijman, Jordi UNSPECIFIED orcid.org/0000-0002-1418-108X UNSPECIFIED Lueker, Jakob UNSPECIFIED UNSPECIFIED UNSPECIFIED Steven, Daniel UNSPECIFIED UNSPECIFIED UNSPECIFIED Sultan, Arian UNSPECIFIED orcid.org/0000-0003-1807-4860 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-674558
DOI:	10.1007/s10840-022-01210-3
Journal or Publication Title:	J. Interv. Card. Electrophysiol.
Volume:	65
Number:	2
Page Range:	S. 403 - 411
Date:	2022
Publisher:	SPRINGER
Place of Publication:	DORDRECHT
ISSN:	1572-8595
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CARDIOVASCULAR EVENTS; RISK-FACTOR; ABLATION; SEDATION Multiple languages Cardiac & Cardiovascular Systems Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/67455