Universität zu Köln

Kohle, Felix ORCID: 0000-0002-4429-0367, Madlener, Marie, Bruno, Emanuel Francesco, Fink, Gereon Rudolf, Limmroth, Volker, Burghaus, Lothar ORCID: 0000-0002-7883-190X and Malter, Michael Peter (2022). Status epilepticus during the COVID-19 pandemic in Cologne, Germany: data from a retrospective, multicentre registry. J. Neurol., 269 (11). S. 5710 - 5720. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-1459

Full text not available from this repository.

Abstract

Background The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe-acute-respiratory-syndrome-coronavirus 2 (SARS-CoV-2), challenges healthcare systems worldwide and impacts not only COVID-19 patients but also other emergencies. To date, data are scarce on the extent to which the COVID-19 pandemic impacted status epilepticus (SE) and its treatment. Objective To assess the influence of the COVID-19 pandemic on the incidence, management and outcome of SE patients. Study design This is a retrospective, multicentre trial, approved by the University of Cologne (21-1443-retro). Methods All SE patients from the urban area of Cologne transmitted to all acute neurological departments in Cologne between 03/2019 and 02/2021 were retrospectively analysed and assessed for patient characteristics, SE characteristics, management, and outcome in the first pandemic year compared to the last pre-pandemic year. Results 157 pre-pandemic (03/2019-02/2020) and 171 pandemic (from 03/2020 to 02/2021) SE patients were included in the analyses. Acute SARS-CoV-2 infections were rarely detected. Patient characteristics, management, and outcome did not reveal significant groupwise differences. In contrast, regarding prehospital management, a prolonged patient transfer to the hospital and variations in SE aetiologies compared to the last pre-pandemic year were observed with less chronic vascular and more cryptogenic and anoxic SE cases. No infections with SARS-CoV-2 occurred during inpatient stays. Conclusions SARS-CoV-2 infections did not directly affect SE patients, but the transfer of SE patients to emergency departments was delayed. Interestingly, SE aetiology rates shifted, which warrants further exploration. Fears of contracting an in-hospital SARS-CoV-2-infection were unfounded due to consequent containment measures.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kohle, Felix UNSPECIFIED orcid.org/0000-0002-4429-0367 UNSPECIFIED Madlener, Marie UNSPECIFIED UNSPECIFIED UNSPECIFIED Bruno, Emanuel Francesco UNSPECIFIED UNSPECIFIED UNSPECIFIED Fink, Gereon Rudolf UNSPECIFIED UNSPECIFIED UNSPECIFIED Limmroth, Volker UNSPECIFIED UNSPECIFIED UNSPECIFIED Burghaus, Lothar UNSPECIFIED orcid.org/0000-0002-7883-190X UNSPECIFIED Malter, Michael Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-679494
DOI:	10.1007/s00415-022-11260-2
Journal or Publication Title:	J. Neurol.
Volume:	269
Number:	11
Page Range:	S. 5710 - 5720
Date:	2022
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1432-1459
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EPIDEMIOLOGY; MORTALITY; ADULTS Multiple languages Clinical Neurology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/67949