Goertz, Lukas, Liebig, Thomas, Siebert, Eberhard ORCID: 0000-0001-7395-6546, Dorn, Franziska, Pflaeging, Muriel, Forbrig, Robert, Pennig, Lenhard, Schlamann, Marc and Kabbasch, Christoph (2022). Long-term clinical and angiographic outcome of the Woven EndoBridge (WEB) for endovascular treatment of intracranial aneurysms. Sci Rep, 12 (1). BERLIN: NATURE PORTFOLIO. ISSN 2045-2322

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Abstract

The Woven EndoBridge (WEB) is a well-established device for endovascular treatment of wide-necked bifurcation aneurysms. The objective was to evaluate the long-term angiographic outcome of the WEB and to identify factors that influence aneurysm occlusion. Patient, aneurysm and procedural characteristics of 213 consecutive patients treated with the WEB at three German tertiary care centers between 2011 and 2020 were retrospectively reviewed. Aneurysm occlusion was determined immediately after the procedure, at mid-term (<= 12 months) and at long-term (> 12 months) follow-up. Among 182 included aneurysms (mean diameter: 7.0 +/- 2.4, mean neck width: 4.3 +/- 1.6 mm), 29.7% were ruptured. The novel WEB 17 was used in 41.8%, and 11.0% were treated in combination with coiling and/or stenting. Complete and adequate occlusions were observed in 101/155 (65.2%) and 133/155 (85.8%) at mid-term, respectively, and in 59/94 (62.8%) and 87/94 (92.6%) at long-term follow-up (median: 19 months), respectively. Among 92 patients available for both mid- and long-term follow-up, occlusion was stable in 72.8%, improved in 16.3% and worsened in 10.9%. There were no major recurrences leading to aneurysm remnants between mid- and long-term follow-up. Retreatment was performed in 10/155 (6.5%) during mid-term and in 1/94 (1.0%) during long-term follow-up. The WEB provides durable aneurysm occlusion at the long-term. Nevertheless, follow-up imaging is necessary to identify late recurrences that may occur in around 10%.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Goertz, LukasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Liebig, ThomasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Siebert, EberhardUNSPECIFIEDorcid.org/0000-0001-7395-6546UNSPECIFIED
Dorn, FranziskaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pflaeging, MurielUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Forbrig, RobertUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pennig, LenhardUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schlamann, MarcUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kabbasch, ChristophUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-681886
DOI: 10.1038/s41598-022-14945-w
Journal or Publication Title: Sci Rep
Volume: 12
Number: 1
Date: 2022
Publisher: NATURE PORTFOLIO
Place of Publication: BERLIN
ISSN: 2045-2322
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
CEREBRAL ANEURYSMS; RECURRENCES; SAFETY; SERIESMultiple languages
Multidisciplinary SciencesMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/68188

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