Universität zu Köln

Empana, Jean-Philippe, Lerner, Ivan, Valentin, Eugenie, Folke, Fredrik, Boettiger, Bernd, Gislason, Gunnar ORCID: 0000-0002-0548-402X, Jonsson, Martin ORCID: 0000-0002-3539-8317, Ringh, Mattias, Beganton, Frankie, Bougouin, Wulfran, Marijon, Eloi, Blom, Marieke, Tan, Hanno and Jouven, Xavier (2022). Incidence of Sudden Cardiac Death in the European Union. J. Am. Coll. Cardiol., 79 (18). S. 1818 - 1828. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1558-3597

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Abstract

BACKGROUND Although sudden cardiac death (SCD) is recognized as a high-priority public health topic, reliable estimates of the incidence of SCD or, more broadly, out-of-hospital cardiac arrest (OHCA), in the population are scarce, especially in the European Union. OBJECTIVES The study objective was to determine the incidence of SCD and OHCA in the European Union. METHODS The study examined 4 large (ie, >2 million inhabitants) European population-based prospective registries collecting emergency medical services (EMS)-attended (ie, with attempted resuscitation) OHCA and SCD (OHCA without obvious extracardiac causes) for >5 consecutive years from January 2012 to December 2017 in the Paris region (France), the North Holland region (the Netherlands), the Stockholm region (Sweden), and in all of Denmark. RESULTS The average annual incidence of SCD in the 4 registries ranged from 36.8 per 100,000 (95% CI: 23.5-50.1 per 100,000) to 39.7 per 100,000 (95% CI: 32.6-46.8 per 100,000). When extrapolating to each European country and accounting for age and sex, this yields to 249,538 SCD cases per year (95% CI: 155,377-343,719 SCD cases per year). The average annual incidence of OHCA in the 4 registries ranged from 47.8 per 100,000 (95% CI: 21.2-74.4 per 100,000) to 57.9 per 100,000 (95% CI: 19.6-96.3 per 100,000), corresponding to 343,496 OHCA cases per year (95% CI: 216,472-464,922 OHCA cases per year) in the European Union. Incidence rates of SCD and OHCA increased with age and were systematically higher in men compared with women. CONCLUSIONS By combining data from 4 large, population-based registries with at least 5 years of data collection, this study provided an estimate of the incidence of SCD and OHCA in the European Union. (C) 2022 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Empana, Jean-Philippe UNSPECIFIED UNSPECIFIED UNSPECIFIED Lerner, Ivan UNSPECIFIED UNSPECIFIED UNSPECIFIED Valentin, Eugenie UNSPECIFIED UNSPECIFIED UNSPECIFIED Folke, Fredrik UNSPECIFIED UNSPECIFIED UNSPECIFIED Boettiger, Bernd UNSPECIFIED UNSPECIFIED UNSPECIFIED Gislason, Gunnar UNSPECIFIED orcid.org/0000-0002-0548-402X UNSPECIFIED Jonsson, Martin UNSPECIFIED orcid.org/0000-0002-3539-8317 UNSPECIFIED Ringh, Mattias UNSPECIFIED UNSPECIFIED UNSPECIFIED Beganton, Frankie UNSPECIFIED UNSPECIFIED UNSPECIFIED Bougouin, Wulfran UNSPECIFIED UNSPECIFIED UNSPECIFIED Marijon, Eloi UNSPECIFIED UNSPECIFIED UNSPECIFIED Blom, Marieke UNSPECIFIED UNSPECIFIED UNSPECIFIED Tan, Hanno UNSPECIFIED UNSPECIFIED UNSPECIFIED Jouven, Xavier UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-691182
DOI:	10.1016/j.jacc.2022.02.041
Journal or Publication Title:	J. Am. Coll. Cardiol.
Volume:	79
Number:	18
Page Range:	S. 1818 - 1828
Date:	2022
Publisher:	ELSEVIER SCIENCE INC
Place of Publication:	NEW YORK
ISSN:	1558-3597
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ARREST INCIDENCE; SURVIVAL RATES; CARDIOPULMONARY; ASSOCIATION; STATEMENT; REGISTRY Multiple languages Cardiac & Cardiovascular Systems Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/69118