Universität zu Köln

Busch, Jonas, Schmidt, Stefanie, Albers, Peter, Heinzelbecker, Julia ORCID: 0000-0001-8993-7171, Kliesch, Sabine, Lackner, Julia, Pfister, David, Ruf, Christian, Winter, Christian, Zengerling, Friedemann and Beyersdorff, Dirk (2022). Can magnetic resonance imaging replace conventional computerized tomography for follow-up of patients with testicular cancer? A systematic review. World J. Urol., 40 (12). S. 2843 - 2853. NEW YORK: SPRINGER. ISSN 1433-8726

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Abstract

Purpose Follow-up protocols for patients with testicular cancer (TC) have significantly reduced the number of cross-sectional imaging studies to reduce radiation exposure. At present, it is unclear whether magnetic resonance imaging (MRI) could replace conventional computerized tomography (CT) imaging. The objective of this study is to summarize the scientific evidence on this topic and to review guideline recommendations with regard to the use of MRI. Methods A systematic literature review was performed searching Medline and Cochrane databases for prospective studies on patients with TC in the follow-up care (last search in February 2021). Additionally, guideline recommendations for TC were screened. Data extraction and quality assessment of included studies were performed and used for a descriptive presentation of results. Results A total of four studies including two ongoing trials were identified. Overall, the scientific evidence of prospective comparative studies is based on 102 patients. Data suggest that abdominal imaging with MRI can replace conventional CT for detection of lymph node metastasis of the retroperitoneum to spare radiation exposure and contrast media application. However, experienced radiologists are needed. Clinical guidelines are aware of the risk of diagnosis-induced secondary malignancy due to CT imaging and some have adapted their recommendations accordingly. Results of the two ongoing trials on 738 patients are expected soon to provide more reliable results on this topic. Conclusions There is growing evidence that abdominopelvic MRI imaging can replace CT imaging during follow-up of patients with TC in order to reduce radiation exposure and diagnosis-induced secondary malignancy.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Busch, Jonas UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmidt, Stefanie UNSPECIFIED UNSPECIFIED UNSPECIFIED Albers, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Heinzelbecker, Julia UNSPECIFIED orcid.org/0000-0001-8993-7171 UNSPECIFIED Kliesch, Sabine UNSPECIFIED UNSPECIFIED UNSPECIFIED Lackner, Julia UNSPECIFIED UNSPECIFIED UNSPECIFIED Pfister, David UNSPECIFIED UNSPECIFIED UNSPECIFIED Ruf, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Winter, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Zengerling, Friedemann UNSPECIFIED UNSPECIFIED UNSPECIFIED Beyersdorff, Dirk UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-692378
DOI:	10.1007/s00345-022-03931-6
Journal or Publication Title:	World J. Urol.
Volume:	40
Number:	12
Page Range:	S. 2843 - 2853
Date:	2022
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1433-8726
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EVIDENCE-BASED RECOMMENDATIONS; LYMPH-NODES; DIAGNOSIS; MRI Multiple languages Urology & Nephrology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/69237