Universität zu Köln

Foldyna, Borek, Uhlig, Johannes, Gohmann, Robin, Lucke, Christian, Mayrhofer, Thomas ORCID: 0000-0001-6287-5185, Lehmkuhl, Lukas, Natale, Luigi, Vliegenthart, Rozemarijn, Lotz, Joachim ORCID: 0000-0002-1412-2741, Salgado, Rodrigo ORCID: 0000-0003-4060-1612, Francone, Marco ORCID: 0000-0002-7906-3420, Loewe, Christian, Nikolaou, Konstantin, Bamberg, Fabian, Maintz, David, Maurovich-Horvat, Pal, Thiele, Holger, Hoffmann, Udo and Gutberlet, Matthias ORCID: 0000-0003-4879-0438 (2022). Quality and safety of coronary computed tomography angiography at academic and non-academic sites: insights from a large European registry (ESCR MR/CT Registry). Eur. Radiol., 32 (8). S. 5246 - 5256. NEW YORK: SPRINGER. ISSN 1432-1084

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Abstract

Objectives To compare the use of coronary computed tomography angiography (CCTA) between academic and non-academic sites across Europe over the last decade. Methods We analyzed a large multicenter registry (ESCR MR/CT Registry) of stable symptomatic patients who received CCTA 01/2010-01/2020 at 47 (22%) academic and 165 (78%) non-academic sites across 19 European countries. We compared image quality, radiation dose, contrast-media-related adverse events, patient characteristics, CCTA findings, and downstream testing between academic and non-academic sites. Results Among 64,317 included patients (41% female; 60 +/- 13 years), academic sites accounted for most cases in 2010-2014 (52%), while non-academic sites dominated in 2015-2020 (71%). Despite less contemporary technology, non-academic sites maintained low radiation doses (4.76 [2.46-6.85] mSv) with a 30% decline of high-dose scans (> 7 mSv) over time. Academic and non-academic sites both reported diagnostic image quality in 98% of cases and low rate of scan-related adverse events (0.4%). Academic and non-academic sites examined similar patient populations (41% females both; age: 61 +/- 14 vs. 60 +/- 12 years; pretest probability for obstructive CAD: low 21% vs. 23%, intermediate 73% vs. 72%, high 6% both, CAD prevalence on CCTA: 40% vs. 41%). Nevertheless, non-academic sites referred more patients to non-invasive ischemia testing (6.5% vs. 4.2%) and invasive coronary angiography/surgery (8.5% vs. 5.6%). Conclusions Non-academic and academic sites provide safe, high-quality CCTA across Europe, essential to successfully implement the recently updated guidelines for the diagnosis and management of chronic coronary syndromes. However, despite examining similar populations with comparable CAD prevalence, non-academic sites tend to refer more patients to downstream testing.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Foldyna, Borek UNSPECIFIED UNSPECIFIED UNSPECIFIED Uhlig, Johannes UNSPECIFIED UNSPECIFIED UNSPECIFIED Gohmann, Robin UNSPECIFIED UNSPECIFIED UNSPECIFIED Lucke, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Mayrhofer, Thomas UNSPECIFIED orcid.org/0000-0001-6287-5185 UNSPECIFIED Lehmkuhl, Lukas UNSPECIFIED UNSPECIFIED UNSPECIFIED Natale, Luigi UNSPECIFIED UNSPECIFIED UNSPECIFIED Vliegenthart, Rozemarijn UNSPECIFIED UNSPECIFIED UNSPECIFIED Lotz, Joachim UNSPECIFIED orcid.org/0000-0002-1412-2741 UNSPECIFIED Salgado, Rodrigo UNSPECIFIED orcid.org/0000-0003-4060-1612 UNSPECIFIED Francone, Marco UNSPECIFIED orcid.org/0000-0002-7906-3420 UNSPECIFIED Loewe, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Nikolaou, Konstantin UNSPECIFIED UNSPECIFIED UNSPECIFIED Bamberg, Fabian UNSPECIFIED UNSPECIFIED UNSPECIFIED Maintz, David UNSPECIFIED UNSPECIFIED UNSPECIFIED Maurovich-Horvat, Pal UNSPECIFIED UNSPECIFIED UNSPECIFIED Thiele, Holger UNSPECIFIED UNSPECIFIED UNSPECIFIED Hoffmann, Udo UNSPECIFIED UNSPECIFIED UNSPECIFIED Gutberlet, Matthias UNSPECIFIED orcid.org/0000-0003-4879-0438 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-695153
DOI:	10.1007/s00330-022-08639-0
Journal or Publication Title:	Eur. Radiol.
Volume:	32
Number:	8
Page Range:	S. 5246 - 5256
Date:	2022
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1432-1084
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CT ANGIOGRAPHY; ARTERY-DISEASE; HEART Multiple languages Radiology, Nuclear Medicine & Medical Imaging Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/69515