Driemeyer, Candida, Falci, Diego R., Oladele, Rita O., Bongomin, Felix, Ocansey, Bright K., Govender, Nelesh P., Hoenigl, Martin, Gangneux, Jean Pierre, Lass-Florl, Cornelia, Cornely, Oliver A. ORCID: 0000-0001-9599-3137, Alanio, Alexandre, Guinea, Jesus ORCID: 0000-0002-7901-8355, Morrissey, C. Orla, Rautemaa-Richardson, Riina, Chakrabarti, Arunaloke, Meis, Jacques F., Bruns, Caroline ORCID: 0000-0003-4849-2107, Stemler, Jannik and Pasqualotto, Alessandro C. (2022). The current state of clinical mycology in Africa: a European Confederation of Medical Mycology and International Society for Human and Animal Mycology survey. Lancet Microbe, 3 (6). S. E464 - 7. AMSTERDAM: ELSEVIER. ISSN 2666-5247

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Abstract

Africa, although not unique in this context, is a favourable environment for fungal infections, given the high burden of risk factors. An online survey was developed asking about laboratory infrastructure and antifungal drug availability. We received 40 responses (24.4% response rate) of 164 researchers contacted from 21 African countries. Only five institutions (12.5%) of 40 located in Cameroon, Kenya, Nigeria, Sudan, and Uganda potentially fulfilled the minimum laboratory requirements for European Confederation of Medical Mycology Excellence Centre blue status. Difficulties included low access to susceptibility testing for both yeasts and moulds (available in only 30% of institutions) and Aspergillus spp antigen detection (available in only 47.5% of institutions as an in-house or outsourced test), as well as access to mould-active antifungal drugs such as amphotericin B deoxycholate (available for 52.5% of institutions), itraconazole (52.5%), voriconazole (35.0%), and posaconazole (5.0%). United and targeted efforts are crucial to face the growing challenges in clinical mycology.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Driemeyer, CandidaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Falci, Diego R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Oladele, Rita O.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bongomin, FelixUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ocansey, Bright K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Govender, Nelesh P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hoenigl, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gangneux, Jean PierreUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lass-Florl, CorneliaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cornely, Oliver A.UNSPECIFIEDorcid.org/0000-0001-9599-3137UNSPECIFIED
Alanio, AlexandreUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Guinea, JesusUNSPECIFIEDorcid.org/0000-0002-7901-8355UNSPECIFIED
Morrissey, C. OrlaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rautemaa-Richardson, RiinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Chakrabarti, ArunalokeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Meis, Jacques F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bruns, CarolineUNSPECIFIEDorcid.org/0000-0003-4849-2107UNSPECIFIED
Stemler, JannikUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pasqualotto, Alessandro C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-697977
DOI: 10.1016/S2666-5247(21)00190-7
Journal or Publication Title: Lancet Microbe
Volume: 3
Number: 6
Page Range: S. E464 - 7
Date: 2022
Publisher: ELSEVIER
Place of Publication: AMSTERDAM
ISSN: 2666-5247
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
SERIOUS FUNGAL-INFECTIONS; SUB-SAHARAN AFRICA; LABORATORY PRACTICES; CRYPTOCOCCAL MENINGITIS; BURDEN; DISEASE; HEALTH; CHALLENGES; RESISTANCEMultiple languages
Infectious Diseases; MicrobiologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/69797

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