Universität zu Köln

Journal Article

Barnes, Christopher O., Schoofs, Till, Gnanapragasam, Priyanthi N. P., Golijanin, Jovana, Huey-Tubman, Kathryn E., Gruell, Henning, Schommers, Philipp ORCID: 0000-0003-3375-6800, Suh-Toma, Nina, Lee, Yu Erica, Lorenzi, Julio C. Cetrulo, Piechocka-Trocha, Alicja, Scheid, Johannes F., Jr, Anthony P. West, Walker, Bruce D., Seaman, Michael S., Klein, Florian ORCID: 0000-0003-1376-1792, Nussenzweig, Michel C. and Bjorkman, Pamela J. (2022). A naturally arising broad and potent CD4-binding site antibody with low somatic mutation. Sci. Adv., 8 (32). WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 2375-2548

Caskey, Marina ORCID: 0000-0003-1727-8693, Schoofs, Till, Gruell, Henning, Settler, Allison, Karagounis, Theodora ORCID: 0000-0003-1481-9589, Kreider, Edward F., Murrell, Ben ORCID: 0000-0002-0393-4445, Pfeifer, Nico ORCID: 0000-0002-4647-8566, Nogueira, Lilian, Oliveira, Thiago Y., Learn, Gerald H., Cohen, Yehuda Z., Lehmann, Clara, Gillor, Daniel, Shimeliovich, Irma, Unson-O'Brien, Cecilia, Weiland, Daniela, Robles, Alexander, Kuemmerle, Tim, Wyen, Christoph, Levin, Rebeka, Witmer-Pack, Maggi, Eren, Kemal, Ignacio, Caroline, Kiss, Szilard ORCID: 0000-0003-3433-8432, West, Anthony P., Jr., Mouquet, Hugo ORCID: 0000-0002-4230-610X, Zingman, Barry S., Gulick, Roy M., Keler, Tibor, Bjorkman, Pamela J., Seaman, Michael S., Hahn, Beatrice H., Faetkenheuer, Gerd, Schlesinger, Sarah J., Nussenzweig, Michel C. and Kleine, Florian (2017). Antibody 10-1074 suppresses viremia in HIV-1-infected individuals. Nat. Med., 23 (2). S. 185 - 192. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1546-170X

Dam, Kim-Marie A., Barnes, Christopher O., Gristick, Harry B., Schoofs, Till, Gnanapragasam, Priyanthi N. P., Nussenzweig, Michel C. and Bjorkman, Pamela J. (2022). HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design. Nat. Commun., 13 (1). BERLIN: NATURE PORTFOLIO. ISSN 2041-1723

Freund, Natalia T., Horwitz, Joshua A., Nogueira, Lilian, Sievers, Stuart A., Scharf, Louise, Scheid, Johannes F., Gazumyan, Anna, Liu, Cassie ORCID: 0000-0003-3907-9409, Velinzon, Klara, Goldenthal, Ariel, Sanders, Rogier W., Moore, John P., Bjorkman, Pamela J., Seaman, Michael S., Walker, Bruce D., Klein, Florian and Nussenzweig, Michel C. (2015). A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo. PLoS Pathog., 11 (10). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1553-7374

Gristick, Harry B., von Boehmer, Lotta ORCID: 0000-0001-8018-1814, West, Anthony P., Jr., Schamber, Michael, Gazumyan, Anna, Golijanin, Jovana, Seaman, Michael S., Faetkenheuer, Gerd, Klein, Florian, Nussenzweig, Michel C. and Bjorkman, Pamela J. (2016). Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site. Nat. Struct. Mol. Biol., 23 (10). S. 906 - 916. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1545-9985

Horwitz, Joshua A., Halper-Stromberg, Ariel, Mouquet, Hugo ORCID: 0000-0002-4230-610X, Gitlin, Alexander D., Tretiakova, Anna, Eisenreich, Thomas R., Malbec, Marine, Gravemann, Sophia, Billerbeck, Eva, Dorner, Marcus ORCID: 0000-0003-0321-4226, Buening, Hildegard, Schwartz, Olivier, Knops, Elena, Kaiser, Rolf, Seaman, Michael S., Wilson, James M., Rice, Charles M., Ploss, Alexander ORCID: 0000-0001-9322-7252, Bjorkman, Pamela J., Klein, Florian and Nussenzweig, Michel C. (2013). HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice. Proc. Natl. Acad. Sci. U. S. A., 110 (41). S. 16538 - 16544. WASHINGTON: NATL ACAD SCIENCES. ISSN 0027-8424

Klein, Florian, Nogueira, Lilian, Nishimura, Yoshiaki, Phad, Ganesh, West, Anthony P., Jr., Halper-Stromberg, Ariel, Horwitz, Joshua A., Gazumyan, Anna, Liu, Cassie ORCID: 0000-0003-3907-9409, Eisenreich, Thomas R., Lehmann, Clara ORCID: 0000-0002-7042-1578, Faetkenheuer, Gerd, Williams, Constance, Shingai, Masashi, Martin, Malcolm A., Bjorkman, Pamela J., Seaman, Michael S., Zolla-Pazner, Susan, Hedestam, Gunilla B. Karlsson and Nussenzweig, Michel C. (2014). Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants. J. Exp. Med., 211 (12). S. 2361 - 2373. NEW YORK: ROCKEFELLER UNIV PRESS. ISSN 1540-9538

Mendoza, Pilar, Gruell, Henning, Nogueira, Lilian, Pai, Joy A., Butler, Allison L., Millard, Katrina, Lehmann, Clara, Suarez, Isabelle, Oliveira, Thiago Y., Lorenzi, Julio C. C., Cohen, Yehuda Z., Wyen, Christoph, Kuemmerle, Tim, Karagounis, Theodora ORCID: 0000-0003-1481-9589, Lu, Ching-Lan, Handl, Lisa, Unson-O'Brien, Cecilia, Patel, Roshni, Ruping, Carola, Schlotz, Maike, Witmer-Pack, Maggi, Shimeliovich, Irina, Kremer, Gisela, Thomas, Eleonore, Seaton, Kelly E., Horowitz, Jill, West, Anthony P., Jr., Bjorkman, Pamela J., Tomaras, Georgia D., Gulick, Roy M., Pfeifer, Nico, Faetkenheuer, Gerd, Seaman, Michael S., Klein, Florian, Caskey, Marina and Nussenzweig, Michel C. (2018). Combination therapy with anti-HIV-1 antibodies maintains viral suppression. Nature, 561 (7724). S. 479 - 497. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Scheid, Johannes F., Horwitz, Joshua A., Bar-On, Yotam, Kreider, Edward F., Lu, Ching-Lan, Lorenzi, Julio C. C., Feldmann, Anna, Braunschweig, Malte, Nogueira, Lilian, Oliveira, Thiago ORCID: 0000-0002-2654-0879, Shimeliovich, Irina, Patel, Roshni, Burke, Leah, Cohen, Yehuda Z., Hadrigan, Sonya, Settler, Allison, Witmer-Pack, Maggi, West, Anthony P., Jr., Juelg, Boris ORCID: 0000-0002-4687-9626, Keler, Tibor, Hawthorne, Thomas, Zingman, Barry, Gulick, Roy M., Pfeifer, Nico ORCID: 0000-0002-4647-8566, Learn, Gerald H., Seaman, Michael S., Bjorkman, Pamela J., Klein, Florian, Schlesinger, Sarah J., Walker, Bruce D., Hahn, Beatrice H., Nussenzweig, Michel C. and Caskey, Marina ORCID: 0000-0003-1727-8693 (2016). HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption. Nature, 535 (7613). S. 556 - 573. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Schommers, Philipp ORCID: 0000-0003-3375-6800, Gruell, Henning, Abernathy, Morgan E., Tran, My-Kim, Dingens, Adam S., Gristick, Harry B., Barnes, Christopher O., Schoofs, Till, Schlotz, Maike, Vanshylla, Kanika, Kreer, Christoph, Weiland, Daniela, Holtick, Udo, Scheid, Christof, Valter, Markus M., van Gils, Marit J. ORCID: 0000-0003-3422-8161, Sanders, Rogier W., Vehreschild, Joerg J., Cornely, Oliver A., Lehmann, Clara, Faetkenheuer, Gerd, Seaman, Michael S., Bloom, Jesse D., Bjorkman, Pamela J. and Klein, Florian (2020). Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody. Cell, 180 (3). S. 471 - 512. CAMBRIDGE: CELL PRESS. ISSN 1097-4172

Schommers, Philipp Frederik ORCID: 0000-0003-3375-6800, Gruell, Henning ORCID: 0000-0002-0725-7138, Abernathy, Morgan E. ORCID: 0000-0001-9959-7713, Tran, My-Kim, Dingens, Adam S. ORCID: 0000-0001-9603-9409, Gristick, Harry B., Barnes, Christopher O., Schoofs, Till, Schlotz, Maike, Vanshylla, Kanika ORCID: 0000-0003-4552-9170, Kreer, Christoph ORCID: 0000-0002-9140-9850, Weiland, Daniela, Holtick, Udo ORCID: 0000-0002-5543-0257, Scheid, Christof ORCID: 0009-0007-6539-226X, Valter, Markus M., van Gils, Marit J. ORCID: 0000-0003-3422-8161, Sanders, Rogier W., Vehreschild, Jörg J. ORCID: 0000-0002-5446-7170, Cornely, Oliver A. ORCID: 0000-0001-9599-3137, Lehmann, Clara ORCID: 0000-0002-7042-1578, Fätkenheuer, Gerd ORCID: 0000-0002-5054-1871, Seaman, Michael S. ORCID: 0000-0001-6444-3562, Bloom, Jesse D., Bjorkman, Pamela J. ORCID: 0000-0002-2277-3990 and Klein, Florian ORCID: 0000-0003-1376-1792 (2020). Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody. Cell, 180 (3). 471-489.e22. Cell Press. ISSN 0092-8674

Schoofs, Till, Barnes, Christopher O., Suh-Toma, Nina, Golijanin, Jovana, Schommers, Philipp ORCID: 0000-0003-3375-6800, Gruell, Henning, West, Anthony P., Jr., Bach, Franziska, Lee, Yu Erica, Nogueira, Lilian, Georgiev, Ivelin S., Bailer, Robert T., Czartoski, Julie, Mascola, John R., Seaman, Michael S., McElrath, M. Juliana, Doria-Rose, Nicole A., Klein, Florian, Nussenzweig, Michel C. and Bjorkman, Pamela J. (2019). Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope. Immunity, 50 (6). S. 1513 - 1539. CAMBRIDGE: CELL PRESS. ISSN 1097-4180

Schoofs, Till, Klein, Florian, Braunschweig, Malte, Kreider, Edward F., Feldmann, Anna, Nogueira, Lilian, Oliveira, Thiago ORCID: 0000-0002-2654-0879, Lorenzi, Julio C. C., Parrish, Erica H., Learn, Gerald H., West, Anthony P., Jr., Bjorkman, Pamela J., Schlesinger, Sarah J., Seaman, Michael S., Czartoski, Julie, McElrath, M. Juliana, Pfeifer, Nico ORCID: 0000-0002-4647-8566, Hahn, Beatrice H., Caskey, Marina ORCID: 0000-0003-1727-8693 and Nussenzweig, Michel C. (2016). HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1. Science, 352 (6288). S. 997 - 1002. WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1095-9203

Vanshylla, Kanika ORCID: 0000-0003-4552-9170, Fan, Chengcheng ORCID: 0000-0003-4213-5758, Wunsch, Marie ORCID: 0000-0002-6570-1831, Poopalasingam, Nareshkumar ORCID: 0000-0002-4981-6209, Meijers, Matthijs ORCID: 0000-0002-1876-8064, Kreer, Christoph ORCID: 0000-0002-9140-9850, Kleipass, Franziska ORCID: 0009-0003-7120-6620, Ruchnewitz, Denis ORCID: 0000-0001-5740-6958, Ercanoglu, Meryem S., Gruell, Henning, Muenn, Friederike, Pohl, Kai, Janicki, Hanna, Nolden, Tobias ORCID: 0000-0002-8996-5612, Bartl, Simone, Stein, Saskia C., Augustin, Max, Dewald, Felix, Gieselmann, Lutz, Schommers, Philipp, Schulz, Thomas F., Sander, Leif Erik, Koch, Manuel ORCID: 0000-0002-2962-7814, Luksza, Marta, Laessig, Michael, Bjorkman, Pamela J. and Klein, Florian ORCID: 0000-0003-1376-1792 (2022). Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers. Cell Host Microbe, 30 (1). S. 69 - 94. CAMBRIDGE: CELL PRESS. ISSN 1934-6069

Weber, Timm ORCID: 0000-0003-2079-842X, Potthoff, Julian, Bizu, Sven ORCID: 0000-0003-4839-2472, Labuhn, Maurice, Dold, Leona, Schoofs, Till, Horning, Marcel ORCID: 0000-0003-1468-4645, Ercanoglu, Meryem S., Kreer, Christoph ORCID: 0000-0002-9140-9850, Gieselmann, Lutz ORCID: 0000-0003-3699-3318, Vanshylla, Kanika ORCID: 0000-0003-4552-9170, Langhans, Bettina, Janicki, Hanna, Stroeh, Luisa J., Knops, Elena, Nierhoff, Dirk, Spengler, Ulrich, Kaiser, Rolf, Bjorkman, Pamela J., Krey, Thomas, Bankwitz, Dorothea, Pfeifer, Nico ORCID: 0000-0002-4647-8566, Pietschmann, Thomas, Flyak, Andrew, I and Klein, Florian ORCID: 0000-0003-1376-1792 (2022). Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization. Immunity, 55 (2). S. 341 - 363. CAMBRIDGE: CELL PRESS. ISSN 1097-4180