Universität zu Köln

Journal Article

Bluhm, Julia, Kieback, Elisa, Marino, Stephen F., Oden, Felix, Westermann, Joerg, Chmielewski, Markus, Abken, Hinrich, Uckert, Wolfgang, Hoepken, Uta E. and Rehm, Armin (2018). CAR T Cells with Enhanced Sensitivity to B Cell Maturation Antigen for the Targeting of B Cell Non-Hodgkin's Lymphoma and Multiple Myeloma. Mol. Ther., 26 (8). S. 1906 - 1921. CAMBRIDGE: CELL PRESS. ISSN 1525-0024

Bunse, Mario ORCID: 0000-0002-7554-2520, Pfeilschifter, Janina, Bluhm, Julia, Zschummel, Maria, Joedicke, Jara J., Wirges, Anthea, Stark, Helen ORCID: 0000-0002-5726-3958, Kretschmer, Vivien, Chmielewski, Markus, Uckert, Wolfgang, Abken, Hinrich, Westermann, Joerg, Rehm, Armin ORCID: 0000-0001-7490-1950 and Hoepken, Uta E. (2021). CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin's lymphoma and tumor-supportive follicular T helper cells. Nat. Commun., 12 (1). BERLIN: NATURE RESEARCH. ISSN 2041-1723

Chmielewski, Markus and Abken, Hinrich (2017). CAR T Cells Releasing IL-18 Convert to T-Bet(high) FoxO1(low) Effectors that Exhibit Augmented Activity against Advanced Solid Tumors. Cell Reports, 21 (11). S. 3205 - 3220. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

Chmielewski, Markus and Abken, Hinrich (2016). Release brakes: chimeric antigen receptor T cells with PD-1 switch receptor. Transl. Cancer Res., 5 (3). S. 229 - 233. SHATIN: AME PUBL CO. ISSN 2219-6803

Chmielewski, Markus and Abken, Hinrich (2015). TRUCKs: the fourth generation of CARs. Expert Opin. Biol. Ther., 15 (8). S. 1145 - 1155. ABINGDON: TAYLOR & FRANCIS LTD. ISSN 1744-7682

Chmielewski, Markus, Hahn, Olga, Rappl, Gunter, Nowak, Michael, Schmidt-Wolf, Ingo H., Hombach, Andreas A. and Abken, Hinrich (2012). T Cells That Target Carcinoembryonic Antigen Eradicate Orthotopic Pancreatic Carcinomas Without Inducing Autoimmune Colitis in Mice. Gastroenterology, 143 (4). S. 1095 - 1110. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC. ISSN 0016-5085

Chmielewski, Markus, Hombach, Andreas A. and Abken, Hinrich (2014). Of CARs and TRUCKs: chimeric antigen receptor (CAR) T cells engineered with an inducible cytokine to modulate the tumor stroma. Immunol. Rev., 257 (1). S. 83 - 91. HOBOKEN: WILEY. ISSN 1600-065X

Chmielewski, Markus, Kopecky, Caroline, Hombach, Andreas A. and Abken, Hinrich (2011). IL-12 Release by Engineered T Cells Expressing Chimeric Antigen Receptors Can Effectively Muster an Antigen-Independent Macrophage Response on Tumor Cells That Have Shut Down Tumor Antigen Expression. Cancer Res., 71 (17). S. 5697 - 5707. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 0008-5472

Chmielewski, Markus, Kuehle, Johannes, Chrobok, Danuta, Riet, Nicole, Hallek, Michael and Abken, Hinrich (2019). FimH-based display of functional eukaryotic proteins on bacteria surfaces. Sci Rep, 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

Chmielewski, Markus, Maliar, Amit, Eshhar, Zelig and Abken, Hinrich (2012). CAR's made it to the pancreas. OncoImmunology, 1 (8). S. 1387 - 1390. PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 2162-402X

Grskovic, Ivan, Kutsch, Anna, Frie, Christian, Groma, Gergely, Stermann, Jacek, Schloetzer-Schrehardt, Ursula, Niehoff, Anja ORCID: 0000-0002-4165-0929, Moss, Stephen E., Rosenbaum, Sabrina, Poeschl, Ernst, Chmielewski, Markus, Rappl, Gunter, Abken, Hinrich, Bateman, John F., Cheah, Kathryn S. E., Paulsson, Mats and Brachvogel, Bent (2012). Depletion of Annexin A5, Annexin A6, and Collagen X Causes No Gross Changes in Matrix Vesicle-Mediated Mineralization, but Lack of Collagen X Affects Hematopoiesis and the Th1/Th2 Response. J. Bone Miner. Res., 27 (11). S. 2399 - 2413. HOBOKEN: WILEY-BLACKWELL. ISSN 0884-0431

Hombach, Andreas ORCID: 0000-0001-9328-8442, Barden, Markus, Hannappel, Lisa, Chmielewski, Markus, Rappl, Gunter, Sachinidis, Agapios and Abken, Hinrich (2022). IL12 integrated into the CAR exodomain converts CD8(+) T cells to poly-functional NK-like cells with superior killing of antigen-loss tumors. Mol. Ther., 30 (2). S. 593 - 606. CAMBRIDGE: CELL PRESS. ISSN 1525-0024

Hombach, Andreas A., Goergens, Andre, Chmielewski, Markus, Murke, Florian, Kimpel, Janine ORCID: 0000-0002-5210-7905, Giebel, Bernd ORCID: 0000-0003-2446-948X and Abken, Hinrich (2016). Superior Therapeutic Index in Lymphoma Therapy: CD30(+) CD34(+) Hematopoietic Stem Cells Resist a Chimeric Antigen Receptor T-cell Attack. Mol. Ther., 24 (8). S. 1423 - 1435. CAMBRIDGE: CELL PRESS. ISSN 1525-0024

Kobold, Sebastian, Steffen, Julius, Chaloupka, Michael, Grassmann, Simon, Henkel, Jonas, Castoldi, Raffaella, Zeng, Yi, Chmielewski, Markus, Schmollinger, Jan C., Schnurr, Max, Rothenfusser, Simon, Schendel, Dolores J., Abken, Hinrich, Sustmann, Claudio, Niederfellner, Gerhard, Klein, Christian ORCID: 0000-0001-7594-7280, Bourquin, Carole ORCID: 0000-0003-3862-4583 and Endres, Stefan (2015). Selective Bispecific T Cell Recruiting Antibody and Antitumor Activity of Adoptive T Cell Transfer. JNCI-J. Natl. Cancer Inst., 107 (1). CARY: OXFORD UNIV PRESS INC. ISSN 1460-2105

Ligtenberg, Maarten A., Mougiakakos, Dimitrios, Mukhopadhyay, Madhura, Witt, Kristina, Lladser, Alvaro, Chmielewski, Markus, Riet, Tobias, Abken, Hinrich and Kiessling, Rolf (2016). Coexpressed Catalase Protects Chimeric Antigen Receptor-Redirected T Cells as well as Bystander Cells from Oxidative Stress-Induced Loss of Antitumor Activity. J. Immunol., 196 (2). S. 759 - 767. BETHESDA: AMER ASSOC IMMUNOLOGISTS. ISSN 1550-6606

Maliar, Amit, Servais, Charlotte, Waks, Tova, Chmielewski, Markus, Lavy, Ron, Altevogt, Peter, Abken, Hinrich and Eshhar, Zelig (2012). Redirected T Cells That Target Pancreatic Adenocarcinoma Antigens Eliminate Tumors and Metastases in Mice. Gastroenterology, 143 (5). S. 1375 - 1390. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC. ISSN 1528-0012

Probst, Kristina, Stermann, Jacek, von Bomhard, Inga, Etich, Julia ORCID: 0000-0003-3238-6692, Pitzler, Lena, Niehoff, Anja, Bluhm, Bjoern, Xu, Haifeng C., Lang, Philipp A., Chmielewski, Markus, Abken, Hinrich, Blissenbach, Birgit, Machova, Alzbeta, Papadopoulou, Nikoletta and Brachvogel, Bent (2018). Depletion of Collagen IX Alpha1 Impairs Myeloid Cell Function. Stem Cells, 36 (11). S. 1752 - 1764. HOBOKEN: WILEY. ISSN 1549-4918

Riet, Tobias ORCID: 0000-0002-8211-7071 and Chmielewski, Markus (2022). Regulatory CAR-T cells in autoimmune diseases: Progress and current challenges. Front. Immunol., 13. LAUSANNE: FRONTIERS MEDIA SA. ISSN 1664-3224

Skuljec, Jelena ORCID: 0000-0001-8509-6563, Chmielewski, Markus, Happle, Christine, Habener, Anika, Busse, Mandy, Abken, Hinrich and Hansen, Gesine (2017). Chimeric Antigen Receptor-Redirected Regulatory T Cells Suppress Experimental Allergic Airway Inflammation, a Model of Asthma. Front. Immunol., 8. LAUSANNE: FRONTIERS MEDIA SA. ISSN 1664-3224

Textor, Ana, Listopad, Joanna J., Le Wuehrmann, Lara, Perez, Cynthia ORCID: 0000-0002-2260-5428, Kruschinski, Anna, Chmielewski, Markus, Abken, Hinrich, Blankenstein, Thomas and Charo, Jehad (2014). Efficacy of CAR T-cell Therapy in Large Tumors Relies upon Stromal Targeting by IFN gamma. Cancer Res., 74 (23). S. 6796 - 6806. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Wagner, Dimitrios L., Koehl, Ulrike, Chmielewski, Markus, Scheid, Christoph and Stripecke, Renata (2022). Review: Sustainable Clinical Development of CAR-T Cells - Switching From Viral Transduction Towards CRISPR-Cas Gene Editing. Front. Immunol., 13. LAUSANNE: FRONTIERS MEDIA SA. ISSN 1664-3224

Thesis

Chmielewski, Markus (2007). Antigen-spezifische T-Zellaktivierung durch rekombinante Immunrezeptoren: Evaluierung in einem immunkompetenten Maus-Modell. PhD thesis, Universität zu Köln.