Universität zu Köln

Journal Article

Bucksch, Karolin, Zachariae, Silke, Aretz, Stefan, Buettner, Reinhard, Holinski-Feder, Elke, Holzapfel, Stefanie, Hueneburg, Robert, Kloor, Matthias, Doeberitz, Magnus von Knebel, Morak, Monika, Moeslein, Gabriela, Nattermann, Jacob, Perne, Claudia, Rahner, Nils, Schmiegel, Wolff, Schulmann, Karsten, Steinke-Lange, Verena, Strassburg, Christian P., Vangala, Deepak B., Weitz, Juergen, Loeffler, Markus and Engel, Christoph ORCID: 0000-0002-7247-282X (2020). Cancer risks in Lynch syndrome, Lynch-like syndrome, and familial colorectal cancer type X: a prospective cohort study. BMC Cancer, 20 (1). LONDON: BMC. ISSN 1471-2407

Dominguez-Valentin, Mev ORCID: 0000-0001-7856-0057, Crosbie, Emma J., Engel, Christoph, Aretz, Stefan, Macrae, Finlay, Winship, Ingrid, Capella, Gabriel, Thomas, Huw, Nakken, Sigve ORCID: 0000-0001-8468-2050, Hovig, Eivind, Nielsen, Maartje, Sijmons, Rolf H., Bertario, Lucio, Bonanni, Bernardo, Tibiletti, Maria Grazia, Cavestro, Giulia Martina, Mints, Miriam, Gluck, Nathan, Katz, Lior, Heinimann, Karl, Vaccaro, Carlos A., Green, Kate, Lalloo, Fiona, Hill, James, Schmiegel, Wolff, Vangala, Deepak, Perne, Claudia, Strauss, Hans-Georg, Tecklenburg, Johanna, Holinski-Feder, Elke, Steinke-Lange, Verena, Mecklin, Jukka-Pekka, Plazzer, John-Paul, Pineda, Marta, Navarro, Matilde, Brunet Vidal, Joan, Kariv, Revital, Rosner, Guy, Alejandra Pinero, Tamara, Laura Gonzalez, Maria, Kalfayan, Pablo, Ryan, Neil, Ten Broeke, Sanne W., Jenkins, Mark A., Sunde, Lone, Bernstein, Inge, Burn, John, Greenblatt, Marc, Cappel, Wouter H. de Vos tot Nederveen, Della Valle, Adriana, Lopez-Koestner, Francisco, Alvarez, Karin, Buettner, Reinhard, Goergens, Heike, Morak, Monika, Holzapfel, Stefanie, Hueneburg, Robert, Doeberitz, Magnus von Knebel, Loeffler, Markus, Rahner, Nils, Weitz, Jurgen, Pylvanainen, Kirsi ORCID: 0000-0003-4399-9283, Renkonen-Sinisalo, Laura, Lepisto, Anna, Auranen, Annika, Hopper, John L., Win, Aung Ko, Haile, Robert W., Lindor, Noralane M., Gallinger, Steven, Le Marchand, Loic, Newcomb, Polly A., Figueiredo, Jane C., Thibodeau, Stephen N., Therkildsen, Christina, Okkels, Henrik, Ketabi, Zohreh, Denton, Oliver G., Rodland, Einar Andreas, Vasen, Hans, Neffa, Florencia, Esperon, Patricia, Tjandra, Douglas, Moeslein, Gabriela, Sampson, Julian R., Evans, D. Gareth, Seppala, Toni T. and Moller, Pal . Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report. Genet. Med.. LONDON: SPRINGERNATURE. ISSN 1530-0366

Dominguez-Valentin, Mev ORCID: 0000-0001-7856-0057, Plazzer, John-Paul ORCID: 0000-0001-5114-4301, Sampson, Julian R., Engel, Christoph ORCID: 0000-0002-7247-282X, Aretz, Stefan ORCID: 0000-0002-5228-1890, Jenkins, Mark A., Sunde, Lone ORCID: 0000-0002-8479-165X, Bernstein, Inge, Capella, Gabriel ORCID: 0000-0002-4669-7320, Balaguer, Francesc ORCID: 0000-0002-0206-0539, Macrae, Finlay, Winship, Ingrid M., Thomas, Huw, Evans, Dafydd Gareth, Burn, John, Greenblatt, Marc, Cappel, Wouter H. de Vos Tot Nederveen, Sijmons, Rolf H., Nielsen, Maartje, Bertario, Lucio, Bonanni, Bernardo, Tibiletti, Maria Grazia, Cavestro, Giulia Martina, Lindblom, Annika, Della Valle, Adriana, Lopez-Kostner, Francisco, Alvarez, Karin, Gluck, Nathan, Katz, Lior, Heinimann, Karl, Vaccaro, Carlos A., Nakken, Sigve ORCID: 0000-0001-8468-2050, Hovig, Eivind ORCID: 0000-0002-9103-1077, Green, Kate, Lalloo, Fiona, Hill, James, Vasen, Hans F. A., Perne, Claudia, Buettner, Reinhard, Goergens, Heike, Holinski-Feder, Elke, Morak, Monika, Holzapfel, Stefanie, Hueneburg, Robert, Doeberitz, Magnus von Knebel, Loeffler, Markus, Rahner, Nils, Weitz, Juergen, Steinke-Lange, Verena, Schmiegel, Wolff, Vangala, Deepak ORCID: 0000-0002-4175-5683, Crosbie, Emma J., Pineda, Marta, Navarro, Matilde, Brunet, Joan, Moreira, Leticia ORCID: 0000-0002-4518-8591, Sanchez, Ariadna ORCID: 0000-0003-0409-1328, Serra-Burriel, Miquel ORCID: 0000-0001-8595-1224, Mints, Miriam, Kariv, Revital, Rosner, Guy, Pinero, Tamara Alejandra, Pavicic, Walter Hernan, Kalfayan, Pablo, ten Broeke, Sanne W., Mecklin, Jukka-Pekka, Pylvanainen, Kirsi, Renkonen-Sinisalo, Laura, Lepisto, Anna, Peltomaki, Paivi ORCID: 0000-0001-8819-2980, Hopper, John L., Win, Aung Ko, Buchanan, Daniel D., Lindor, Noralane M., Gallinger, Steven, Le Marchand, Loic, Newcomb, Polly A., Figueiredo, Jane C., Thibodeau, Stephen N., Therkildsen, Christina, Hansen, Thomas V. O., Lindberg, Lars, Rodland, Einar Andreas, Neffa, Florencia, Esperon, Patricia, Tjandra, Douglas, Moslein, Gabriela, Seppala, Toni T. and Moller, Pal (2021). No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study. J. Clin. Med., 10 (13). BASEL: MDPI. ISSN 2077-0383

Engel, Christoph ORCID: 0000-0002-7247-282X, Ahadova, Aysel, Seppala, Toni T. ORCID: 0000-0002-4940-3498, Aretz, Stefan ORCID: 0000-0002-5228-1890, Bigirwamungu-Bargeman, Marloes, Blaeker, Hendrik, Bucksch, Karolin, Buettner, Reinhard, Cappel, Wouter T. De Vos Tot Nederveen, Endris, Volker, Holinski-Feder, Elke, Holzapfel, Stefanie, Hueneburg, Robert, Jacobs, Maarten A. J. M., Koornstra, Jan J., Langers, Alexandra M., Lepisto, Anna, Morak, Monika, Moeslein, Gabriela, Peltomaeki, Paivi, Pylvaenaeinen, Kirsi, Rahner, Nils, Renkonen-Sinisalo, Laura, Schulmann, Karsten, Steinke-Lange, Verena, Stenzinger, Albrecht, Strassburg, Christian P., van de Meeberg, Paul C., van Kouwen, Mariette, van Leerdam, Monique ORCID: 0000-0002-5719-3208, Vangala, Deepak B., Vecht, Juda, Verhulst, Marie-Louise, Doeberitz, Magnus von Knebel, Weitz, Juergen, Zachariae, Silke, Loeffler, Markus, Mecklin, Jukka-Pekka ORCID: 0000-0003-4895-2249, Kloor, Matthias and Vasen, Hans F. (2020). Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome. Gastroenterology, 158 (5). S. 1326 - 1334. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC. ISSN 1528-0012

Engel, Christoph ORCID: 0000-0002-7247-282X, Loeffler, Markus, Steinke, Verena, Rahner, Nils, Holinski-Feder, Elke, Dietmaier, Wolfgang, Schackert, Hans K., Goergens, Heike, Doeberitz, Magnus von Knebel, Goecke, Timm O., Schmiegel, Wolff, Buettner, Reinhard, Moeslein, Gabriela, Letteboer, Tom G. W., Garcia, Encarna Gomez, Hes, Frederik J., Hoogerbrugge, Nicoline ORCID: 0000-0003-2393-8141, Menko, Fred H., van Os, Theo A. M., Sijmons, Rolf H., Wagner, Anja, Kluijt, Irma, Propping, Peter and Vasen, Hans F. A. (2012). Risks of Less Common Cancers in Proven Mutation Carriers With Lynch Syndrome. J. Clin. Oncol., 30 (35). S. 4409 - 4416. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. ISSN 0732-183X

Engel, Christoph ORCID: 0000-0002-7247-282X, Vasen, Hans F., Seppala, Toni, Aretz, Stefan ORCID: 0000-0002-5228-1890, Bigirwamungu-Bargeman, Marloes, de Boer, Sybrand Y., Bucksch, Karolin, Buttner, Reinhard, Holinski-Feder, Elke, Holzapfel, Stefanie, Hueneburg, Robert, Jacobs, Maarten A. J. M., Jarvinen, Heikki, Kloor, Matthias, Doeberitz, Magnus von Knebel, Koornstra, Jan J., van Kouwen, Mariette, Langers, Alexandra M., van de Meeberg, Paul C., Morak, Monika, Moeslein, Gabriela, Nagengast, Fokko M., Pylvanainen, Kirsi ORCID: 0000-0003-4399-9283, Rahner, Nils, Renkonen-Sinisalo, Laura, Sanduleanu, Silvia, Schackert, Hans K., Schmiegel, Wolff, Schulmann, Karsten, Steinke-Lange, Verena, Strassburg, Christian P., Vecht, Juda, Verhulst, Marie-Louise, Cappel, Wouter de Vos Tot Nederveen, Zachariae, Silke, Mecklin, Jukka-Pekka ORCID: 0000-0003-4895-2249 and Loeffler, Markus (2018). No Difference in Colorectal Cancer Incidence or Stage at Detection by Colonoscopy Among 3 Countries With Different Lynch Syndrome Surveillance Policies. Gastroenterology, 155 (5). S. 1400 - 1412. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC. ISSN 1528-0012

Gross, Gerd E., Werner, Ricardo N., Valle, Gabriela L. Avila, Bickel, Markus, Brockmeyer, Norbert H., Doubek, Klaus, Gallwas, Julia, Gieseking, Friederike, Haase, Heidemarie, Hillemanns, Peter, Ikenberg, Hans, Jongen, Johannes, Kaufmann, Andreas M., Klussmann, Jens Peter ORCID: 0000-0002-8223-7954, Doeberitz, Magnus von Knebel, Knuf, Markus, Kollges, Ralf, Laws, Hans-Juergen, Mikolajczyk, Rafael ORCID: 0000-0003-1271-7204, Neis, Klaus J., Petry, Karl-Ulrich, Pfister, Herbert, Schlaeger, Martin, Schneede, Peter, Schneider, Achim, Smola, Sigrun, Tiews, Sven, Nast, Alexander, Gaskins, Matthew and Wieland, Ulrike (2021). German evidence and consensus-based (S3) guideline: Vaccination recommendations for the prevention of HPV-associated lesions. J. Dtsch. Dermatol. Ges., 19 (3). S. 479 - 494. HOBOKEN: WILEY. ISSN 1610-0387

Klein, Sebastian ORCID: 0000-0002-2188-9377, Quaas, Alexander, Quantius, Jennifer, Loeser, Heike, Meinel, Jorn, Peifer, Martin, Wagner, Steffen ORCID: 0000-0003-0873-1601, Gattenloehner, Stefan, Wittekindt, Claus, Doeberitz, Magnus von Knebel, Prigge, Elena-Sophie, Langer, Christine, Noh, Ka-Won, Maltseva, Margaret, Reinhardt, Hans Christian, Buettner, Reinhard, Klussmann, Jens Peter ORCID: 0000-0002-8223-7954 and Wuerdemann, Nora (2021). Deep Learning Predicts HPV Association in Oropharyngeal Squamous Cell Carcinomas and Identifies Patients with a Favorable Prognosis Using Regular H&E Stains. Clin. Cancer Res., 27 (4). S. 1131 - 1139. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Reuschenbach, Miriam, Huebbers, Christian U., Prigge, Elena-Sophie, Bermejo, Justo Lorenzo, Kalteis, Martin S., Preuss, Simon F., Seuthe, Inga M. C., Kolligs, Jutta, Speel, Ernst-Jan M., Olthof, Nadine, Kremer, Bernd, Wagner, Steffen, Klussmann, Jens P., Vinokurova, Svetlana and Doeberitz, Magnus von Knebel (2015). Methylation status of HPV16 E2-binding sites classifies subtypes of HPV-associated oropharyngeal cancers. Cancer, 121 (12). S. 1966 - 1977. HOBOKEN: WILEY-BLACKWELL. ISSN 1097-0142

Seppala, Toni T., Dominguez-Valentin, Mev, Crosbie, Emma J., Engel, Christoph ORCID: 0000-0002-7247-282X, Aretz, Stefan ORCID: 0000-0002-5228-1890, Macrae, Finlay, Winship, Ingrid, Capella, Gabriel, Thomas, Huw, Hovig, Eivind ORCID: 0000-0002-9103-1077, Nielsen, Maartje, Sijmons, Rolf H., Bertario, Lucio, Bonanni, Bernardo, Tibiletti, Maria G., Cavestro, Giulia M., Mints, Miriam, Gluck, Nathan, Katz, Lior, Heinimann, Karl, Vaccaro, Carlos A., Green, Kate, Lalloo, Fiona, Hill, James, Schmiegel, Wolff, Vangala, Deepak ORCID: 0000-0002-4175-5683, Perne, Claudia, Strauss, Hans-Georg, Tecklenburg, Johanna, Holinski-Feder, Elke, Steinke-Lange, Verena, Mecklin, Jukka-Pekka, Plazzer, John-Paul, Pineda, Marta, Navarro, Matilde, Vida, Joan B., Kariv, Revital, Rosner, Guy, Pinero, Tamara A., Pavicic, Walter, Kalfayan, Pablo, Ten Broeke, Sanne W., Jenkins, Mark A., Sunde, Lone ORCID: 0000-0002-8479-165X, Bernstein, Inge, Burn, John, Greenblatt, Marc, Cappel, Wouter H. de Vos Tot Nederveen, Della Valle, Adriana, Lopez-Koestner, Francisco, Alvarez, Karin, Buettner, Reinhard, Goergens, Heike, Morak, Monika, Holzapfel, Stefanie, Hueneburg, Robert, Doeberitz, Magnus von Knebel, Loeffler, Markus, Redler, Silke, Weitz, Jurgen, Pylvaenaeinen, Kirsi, Renkonen-Sinisalo, Laura, Lepisto, Anna, Hopper, John L., Win, Aung K., Lindor, Noralane M., Gallinger, Steven, Marchand, Loic Le, Newcomb, Polly A., Figueiredo, Jane C., Thibodeau, Stephen N., Therkildsen, Christina, Wadt, Karin A. W., Mourits, Marian J. E., Ketabi, Zohreh, Denton, Oliver G., Rodland, Einar A., Vasen, Hans, Neffa, Florencia, Esperon, Patricia, Tjandra, Douglas, Moeslein, Gabriela, Rokkones, Erik, Sampson, Julian R., Evans, D. G. and Moller, Pal (2021). Uptake of hysterectomy and bilateral salpingooophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report. Eur. J. Cancer, 148. S. 124 - 134. OXFORD: ELSEVIER SCI LTD. ISSN 1879-0852

Speel, Ernst-Jan M., Reuschenbach, Miriam, Huebbers, Christian U., Prigge, Elena-Sophie, Bermejo, Justo L., Kalteis, Simon, Preuss, Simon, Kolligs, Jutta, Olthof, Nadine C., Kremer, Bernd, Wagner, Steffen, Klussmann, Jens P., Vinokurova, Svetlana and Doeberitz, Magnus von Knebel (2015). Methylation status of HPV16 E2-binding sites identifies subtypes of HPV-associated oropharyngeal squamous cell carcinomas. Cancer Res., 75. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Wagner, Steffen, Prigge, Elena-Sophie, Wuerdemann, Nora, Reder, Henrike, Bushnak, Ayman, Sharma, Shachi Jenny, Obermueller, Theresa, Doeberitz, Magnus von Knebel, Dreyer, Thomas, Gattenloehner, Stefan, Wolf, Gregor, Pons-Kuehnemann, Joern, Wittekindt, Claus and Klussmann, Jens Peter (2020). Evaluation of p16(INK4a)expression as a single marker to select patients with HPV-driven oropharyngeal cancers for treatment de-escalation. Br. J. Cancer, 123 (7). S. 1114 - 1123. LONDON: SPRINGERNATURE. ISSN 1532-1827

Wittekindt, Claus, Wagner, Steffen, Bushnak, Ayman, Prigge, Elena-Sophie, Doeberitz, Magnus von Knebel, Wuerdemann, Nora, Bernhardt, Katharina, Pons-Kuehnemann, Joern, Maulbecker-Armstrong, Catharina and Klussmann, Jens Peter (2019). Increasing Incidence rates of Oropharyngeal Squamous Cell Carcinoma in Germany and Significance of Disease Burden Attributed to Human Papillomavirus. Cancer Prev. Res., 12 (6). S. 375 - 383. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1940-6215