Universität zu Köln

2022

Cosentino, Katia ORCID: 0000-0002-3796-3500, Hertlein, Vanessa, Jenner, Andreas, Dellmann, Timo, Gojkovic, Milos, Pena-Blanco, Aida, Dadsena, Shashank, Wajngarten, Noel ORCID: 0000-0003-3387-1120, Danial, John S. H., Thevathasan, Jervis Vermal, Mund, Markus, Ries, Jonas ORCID: 0000-0002-6640-9250 and Garcia-Saez, Ana J. (2022). The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation. Mol. Cell, 82 (5). S. 933 - 960. CAMBRIDGE: CELL PRESS. ISSN 1097-4164

Danial, John S. H., Quintana, Yuri, Ros, Uris, Shalaby, Raed, Margheritis, Eleonora G., Ramirez, Sabrina Chumpen, Ungermann, Christian, Garcia-Saez, Ana J. and Cosentino, Katia ORCID: 0000-0002-3796-3500 (2022). Systematic Assessment of the Accuracy of Subunit Counting in Biomolecular Complexes Using Automated Single-Molecule Brightness Analysis. J. Phys. Chem. Lett., 13 (3). S. 822 - 830. WASHINGTON: AMER CHEMICAL SOC. ISSN 1948-7185

Flores-Romero, Hector, Hohorst, Lisa, John, Malina ORCID: 0000-0003-2927-3582, Albert, Marie-Christine, King, Louise E., Beckmann, Laura, Szabo, Tamas, Hertlein, Vanessa, Luo, Xu, Villunger, Andreas ORCID: 0000-0001-8259-4153, Frenzel, Lukas P., Kashkar, Hamid and Garcia-Saez, Ana J. (2022). BCL-2-family protein tBID can act as a BAX-like effector of apoptosis. Embo J., 41 (2). HOBOKEN: WILEY. ISSN 1460-2075

Gueguinou, Maxime ORCID: 0000-0002-5793-2082, Ibrahim, Sajida, Bourgeais, Jerome, Robert, Alison, Pathak, Trayambak, Zhang, Xuexin, Crottes, David, Dupuy, Jacques, Ternant, David, Monbet, Valerie, Guibon, Roseline, Flores-Romero, Hector ORCID: 0000-0003-0996-5717, Lefevre, Antoine, Lerondel, Stephanie, Le Pape, Alain, Dumas, Jean-Francois ORCID: 0000-0002-2293-6606, Frank, Philippe G., Girault, Alban ORCID: 0000-0001-5478-9340, Chautard, Romain, Gueraud, Francoise, Garcia-Saez, Ana J., Ouaissi, Mehdi, Emond, Patrick, Sire, Olivier, Herault, Olivier ORCID: 0000-0002-7419-1124, Fromont-Hankard, Gaelle, Vandier, Christophe, Tougeron, David, Trebak, Mohamed, Raoul, William ORCID: 0000-0002-5040-3372 and Lecomte, Thierry (2022). Curcumin and NCLX inhibitors share anti-tumoral mechanisms in microsatellite-instability-driven colorectal cancer. Cell. Mol. Life Sci., 79 (6). BASEL: SPRINGER BASEL AG. ISSN 1420-9071

Jenner, Andreas, Pena-Blanco, Aida, Salvador-Gallego, Raquel, Ugarte-Uribe, Begona, Zollo, Cristiana, Ganief, Tariq, Bierlmeier, Jan ORCID: 0000-0002-7261-4744, Mund, Marcus, Lee, Jason E., Ries, Jonas ORCID: 0000-0002-6640-9250, Schwarzer, Dirk, Macek, Boris and Garcia-Saez, Ana J. (2022). DRP1 interacts directly with BAX to induce its activation and apoptosis. Embo J., 41 (8). HOBOKEN: WILEY. ISSN 1460-2075

2021

Cosentino, Katia, Hermann, Edward, von Kugelgen, Nicolai, Unsay, Joseph D., Ros, Uris and Garcia-Saez, Ana J. (2021). Force Mapping Study of Actinoporin Effect in Membranes Presenting Phase Domains. Toxins, 13 (9). BASEL: MDPI. ISSN 2072-6651

Dadsena, Shashank ORCID: 0000-0002-0227-5900, Jenner, Andreas and Garcia-Saez, Ana J. (2021). Mitochondrial outer membrane permeabilization at the single molecule level. Cell. Mol. Life Sci., 78 (8). S. 3777 - 3791. BASEL: SPRINGER BASEL AG. ISSN 1420-9071

Dadsena, Shashank ORCID: 0000-0002-0227-5900, King, Louise E ORCID: 0000-0003-2453-8887 and Garcia-Saez, Ana J. ORCID: 0000-0002-3894-5945 (2021). Apoptosis regulation at the mitochondria membrane level. Biochim Biophys Acta Biomembr, 12 (1863). p. 183716. Elsevier.

Dadsena, Shashank ORCID: 0000-0002-0227-5900, Zollo, Cristiana and Garcia-Saez, Ana J. (2021). Mechanisms of mitochondrial cell death. Biochem. Soc. Trans., 49 (2). S. 663 - 675. LONDON: PORTLAND PRESS LTD. ISSN 1470-8752

Murad, Fabronia and Garcia-Saez, Ana J. (2021). Bcl-xL inhibits tBid and Bax via distinct mechanisms. Faraday Discuss., 232. S. 86 - 103. CAMBRIDGE: ROYAL SOC CHEMISTRY. ISSN 1364-5498

Ros, Uris, Pedrera, Lohans and Garcia-Saez, Ana J. (2021). Techniques for studying membrane pores. Curr. Opin. Struct. Biol., 69. S. 108 - 117. LONDON: CURRENT BIOLOGY LTD. ISSN 1879-033X

Wang, Xin, Ros, Uris, Agrawal, Deepti ORCID: 0000-0002-9541-1704, Keller, Eva C., Slotta-Huspenina, Julia, Dill, Veronika, Shen, Bo, Shi, Run ORCID: 0000-0003-4667-4812, Herold, Tobias, Belka, Claus, Misra, Ritu, Bassermann, Florian, Garcia-Saez, Ana J. and Jost, Philipp J. ORCID: 0000-0003-2454-0362 (2021). MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF. Cell Death Differ., 28 (12). S. 3235 - 3251. LONDON: SPRINGERNATURE. ISSN 1476-5403

2020

Flores-Romero, Hector ORCID: 0000-0003-0996-5717 and Garcia-Saez, Ana J. (2020). Lipids glue BAK dimers together. Nat. Struct. Mol. Biol., 27 (11). S. 1003 - 1005. BERLIN: NATURE RESEARCH. ISSN 1545-9985

Flores-Romero, Hector ORCID: 0000-0003-0996-5717, Ros, Uris and Garcia-Saez, Ana J. (2020). Pore formation in regulated cell death. Embo J., 39 (23). HOBOKEN: WILEY. ISSN 1460-2075

Garcia-Saez, Ana J. (2020). THE BCL-2 FAMILY SAGA. Nat. Rev. Mol. Cell Biol., 21 (10). S. 564 - 566. BERLIN: NATURE RESEARCH. ISSN 1471-0080

Garcia-Saez, Ana J. (2020). THE BCL-2 FAMILY SAGA. Nat. Rev. Mol. Cell Biol., 21 (10). S. 565 - 566. LONDON: NATURE PUBLISHING GROUP. ISSN 1471-0080

Kuwana, Tomomi, King, Louise E., Cosentino, Katia, Suess, Julian, Garcia-Saez, Ana J., Gilmore, Andrew P. and Newmeyer, Donald D. (2020). Mitochondrial residence of the apoptosis inducer BAX is more important than BAX oligomerization in promoting membrane permeabilization. J. Biol. Chem., 295 (6). S. 1623 - 1637. ROCKVILLE: AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC. ISSN 1083-351X

Lindenboim, Liora, Grozki, Dan, Amsalem-Zafran, Ayelet R., Pena-Blanco, Aida, Gundersen, Gregg G., Borner, Christoph, Hodzic, Didier, Garcia-Saez, Ana J., Worman, Howard J. and Stein, Reuven (2020). Apoptotic stress induces Bax-dependent, caspase-independent redistribution of LINC complex nesprins. Cell Death Discov., 6 (1). LONDON: SPRINGERNATURE. ISSN 2058-7716

Pena-Blanco, Aida, Haschka, Manuel D., Jenner, Andreas, Zuleger, Theresia, Proikas-Cezanne, Tassula, Villunger, Andreas and Garcia-Saez, Ana J. (2020). Drp1 modulates mitochondrial stress responses to mitotic arrest. Cell Death Differ., 27 (9). S. 2620 - 2635. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-5403

Ros, Uris, Pedrera, Lohans and Garcia-Saez, Ana J. (2020). Partners in Crime: The Interplay of Proteins and Membranes in Regulated Necrosis. Int. J. Mol. Sci., 21 (7). BASEL: MDPI. ISSN 1422-0067

Shalaby, Raed, Flores-Romero, Hector ORCID: 0000-0003-0996-5717 and Garcia-Saez, Ana J. (2020). The Mysteries around the BCL-2 Family Member BOK. Biomolecules, 10 (12). BASEL: MDPI. ISSN 2218-273X

2018

Galluzzi, Lorenzo, Vitale, Ilio, Aaronson, Stuart A., Abrams, John M., Adam, Dieter ORCID: 0000-0002-5668-5032, Agostinis, Patrizia ORCID: 0000-0003-1314-2115, Alnemri, Emad S., Altucci, Lucia, Amelio, Ivano, Andrews, David W., Annicchiarico-Petruzzelli, Margherita ORCID: 0000-0002-4717-4740, Antonov, Alexey V., Arama, Eli, Baehrecke, Eric H., Barlev, Nickolai A., Bazan, Nicolas G., Bernassola, Francesca, Bertrand, Mathieu J. M., Bianchi, Katiuscia, Blagosklonny, Mikhail V., Blomgren, Klas, Borner, Christoph, Boya, Patricia ORCID: 0000-0003-3045-951X, Brenner, Catherine, Campanella, Michelangelo, Candi, Eleonora, Carmona-Gutierrez, Didac ORCID: 0000-0001-7548-7771, Cecconi, Francesco, Chan, Francis K. -M., Chandel, Navdeep S., Cheng, Emily H., Chipuk, Jerry E., Cidlowski, John A., Ciechanover, Aaron, Cohen, Gerald M., Conrad, Marcus ORCID: 0000-0003-1140-5612, Cubillos-Ruiz, Juan R., Czabotar, Peter E., D'Angiolella, Vincenzo, Dawson, Ted M., Dawson, Valina L., De laurenzi, Vincenzo, De Maria, Ruggero ORCID: 0000-0003-2255-0583, Debatin, Klaus-Michael ORCID: 0000-0002-8397-1886, DeBerardinis, Ralph J., Deshmukh, Mohanish, Di Daniele, Nicola, Di Virgilio, Francesco ORCID: 0000-0003-3566-1362, Dixit, Vishva M., Dixon, Scott J., Duckett, Colin S., Dynlacht, Brian D., El-Deiry, Wafik S., Elrod, John W., Fimia, Gian Maria ORCID: 0000-0003-4438-3325, Fulda, Simone ORCID: 0000-0002-0459-6417, Garcia-Saez, Ana J., Garg, Abhishek D., Garrido, Carmen, Gavathiotis, Evripidis ORCID: 0000-0001-6319-8331, Golstein, Pierre ORCID: 0000-0003-1750-3483, Gottlieb, Eyal ORCID: 0000-0002-9770-0956, Green, Douglas R., Greene, Lloyd A., Gronemeyer, Hinrich ORCID: 0000-0001-9454-2449, Gross, Atan, Hajnoczky, Gyorgy, Hardwick, J. Marie, Harris, Isaac S., Hengartner, Michael O., Hetz, Claudio, Ichijo, Hidenori, Jaattela, Marja ORCID: 0000-0001-5950-7111, Joseph, Bertrand, Jost, Philipp J. ORCID: 0000-0003-2454-0362, Juin, Philippe P., Kaiser, William J., Karin, Michael, Kaufmann, Thomas ORCID: 0000-0001-9906-874X, Kepp, Oliver ORCID: 0000-0002-6081-9558, Kimchi, Adi, Kitsis, Richard N., Klionsky, Daniel J., Knight, Richard A., Kumar, Sharad ORCID: 0000-0001-7126-9814, Lee, Sam W., Lemasters, John J., Levine, Beth, Linkermann, Andreas ORCID: 0000-0001-6287-9725, Lipton, Stuart A., Lockshin, Richard A., Lopez-Otin, Carlos ORCID: 0000-0001-6964-1904, Lowe, Scott W., Luedde, Tom, Lugli, Enrico, MacFarlane, Marion, Madeo, Frank, Malewicz, Michal, Malorni, Walter, Manic, Gwenola ORCID: 0000-0003-3759-8029, Marine, Jean-Christophe ORCID: 0000-0003-2433-9837, Martin, Seamus J., Martinou, Jean-Claude, Medema, Jan Paul, Mehlen, Patrick, Meier, Pascal ORCID: 0000-0003-2760-6523, Melino, Sonia, Miao, Edward A., Molkentin, Jeffery D., Moll, Ute M., Munoz-Pinedo, Cristina ORCID: 0000-0002-9120-664X, Nagata, Shigekazu ORCID: 0000-0001-9758-8426, Nunez, Gabriel, Oberst, Andrew, Oren, Moshe, Overholtzer, Michael, Pagano, Michele, Panaretakis, Theocharis, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Penninger, Josef M., Pereira, David M. ORCID: 0000-0003-0384-7592, Pervaiz, Shazib, Peter, Marcus E., Piacentini, Mauro ORCID: 0000-0003-2919-1296, Pinton, Paolo, Prehn, Jochen H. M., Puthalakath, Hamsa ORCID: 0000-0001-5178-1175, Rabinovich, Gabriel A., Rehm, Markus ORCID: 0000-0001-6149-9261, Rizzuto, Rosario, Rodrigues, Cecilia M. P., Rubinsztein, David C., Rudel, Thomas, Ryan, Kevin M., Sayan, Emre, Scorrano, Luca ORCID: 0000-0002-8515-8928, Shao, Feng, Shi, Yufang ORCID: 0000-0001-8964-319X, Silke, John ORCID: 0000-0002-7611-5774, Simon, Hans-Uwe ORCID: 0000-0002-9404-7736, Sistigu, Antonella, Stockwell, Brent R., Strasser, Andreas ORCID: 0000-0002-5020-4891, Szabadkai, Gyorgy, Tait, Stephen W. G., Tang, Daolin, Tavernarakis, Nektarios ORCID: 0000-0002-5253-1466, Thorburn, Andrew, Tsujimoto, Yoshihide, Turk, Boris ORCID: 0000-0002-9007-5764, Vanden Berghe, Tom, Vandenabeele, Peter ORCID: 0000-0002-6669-8822, Heiden, Matthew G. Vander, Villunger, Andreas, Virgin, Herbert W., Vousden, Karen H., Vucic, Domagoj, Wagner, Erwin F., Walczak, Henning ORCID: 0000-0002-6312-4591, Wallach, David, Wang, Ying, Wells, James A., Wood, Will, Yuan, Junying, Zakeri, Zahra, Zhivotovsky, Boris ORCID: 0000-0002-2238-3482, Zitvogel, Laurence, Melino, Gerry and Kroemer, Guido (2018). Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death Differ., 25 (3). S. 486 - 542. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-5403