Universität zu Köln

Journal Article

Ajamian, Lara, Abel, Karen, Rao, Shringar, Vyboh, Kishanda, Garcia-de-Gracia, Francisco, Soto-Rifo, Ricardo, Kulozik, Andreas E., Gehring, Niels H. ORCID: 0000-0001-7792-1164 and Mouland, Andrew J. (2015). HIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA. Biomolecules, 5 (4). S. 2808 - 2840. BASEL: MDPI. ISSN 2218-273X

Boehm, Volker ORCID: 0000-0001-7588-9842, Britto-Borges, Thiago, Steckelberg, Anna-Lena ORCID: 0000-0001-7988-9946, Singh, Kusum K., Gerbracht, Jennifer V. ORCID: 0000-0002-3377-4649, Gueney, Elif, Blazquez, Lorea, Altmueller, Janine, Dieterich, Christoph and Gehring, Niels H. (2018). Exon Junction Complexes Suppress Spurious Splice Sites to Safeguard Transcriptome Integrity. Mol. Cell, 72 (3). S. 482 - 503. CAMBRIDGE: CELL PRESS. ISSN 1097-4164

Boehm, Volker ORCID: 0000-0001-7588-9842 and Gehring, Niels H. ORCID: 0000-0001-7792-1164 (2016). Exon Junction Complexes: Supervising the Gene Expression Assembly Line. Trends Genet., 32 (11). S. 724 - 736. LONDON: ELSEVIER SCIENCE LONDON. ISSN 1362-4555

Boehm, Volker ORCID: 0000-0001-7588-9842, Gerbracht, Jennifer V. ORCID: 0000-0002-3377-4649, Marx, Marie-Charlotte and Gehring, Niels H. ORCID: 0000-0001-7792-1164 (2016). Interrogating the degradation pathways of unstable mRNAs with XRN1-resistant sequences. Nat. Commun., 7. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Boehm, Volker ORCID: 0000-0001-7588-9842, Haberman, Nejc ORCID: 0000-0001-9247-4139, Ottens, Franziska ORCID: 0000-0002-0353-2649, Ule, Jernej ORCID: 0000-0002-2452-4277 and Gehring, Niels H. ORCID: 0000-0001-7792-1164 (2014). 3 ' UTR Length and Messenger Ribonucleoprotein Composition Determine Endocleavage Efficiencies at Termination Codons. Cell Reports, 9 (2). S. 555 - 569. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

Boehm, Volker ORCID: 0000-0001-7588-9842, Kueckelmann, Sabrina ORCID: 0000-0001-8070-8823, Gerbracht, Jennifer, V, Kallabis, Sebastian ORCID: 0000-0003-1580-7109, Britto-Borges, Thiago, Altmueller, Janine, Krueger, Marcus, Dieterich, Christoph and Gehring, Niels H. (2021). SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity. Nat. Commun., 12 (1). BERLIN: NATURE PORTFOLIO. ISSN 2041-1723

Burgute, Bhagyashri D., Peche, Vivek S., Steckelberg, Anna-Lena ORCID: 0000-0001-7988-9946, Gloeckner, Gernot, Gassen, Berthold, Gehring, Niels H. ORCID: 0000-0001-7792-1164 and Noegel, Angelika A. (2014). NKAP is a novel RS-related protein that interacts with RNA and RNA binding proteins. Nucleic Acids Res., 42 (5). S. 3177 - 3194. OXFORD: OXFORD UNIV PRESS. ISSN 1362-4962

Clerici, Marcello, Deniaud, Aurelien, Boehm, Volker ORCID: 0000-0001-7588-9842, Gehring, Niels H. ORCID: 0000-0001-7792-1164, Schaffitzel, Christiane and Cusack, Stephen ORCID: 0000-0002-9324-0796 (2014). Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2. Nucleic Acids Res., 42 (4). S. 2673 - 2687. OXFORD: OXFORD UNIV PRESS. ISSN 1362-4962

Efstathiou, Sotirios, Ottens, Franziska ORCID: 0000-0002-0353-2649, Schuetter, Lena-Sophie, Ravanelli, Sonia ORCID: 0000-0002-8511-9339, Charmpilas, Nikolaos, Gutschmidt, Aljona, Le Pen, Jeremie ORCID: 0000-0001-7025-9526, Gehring, Niels H., Miska, Eric A., Boucas, Jorge and Hoppe, Thorsten . ER-associated RNA silencing promotes ER quality control. Nat. Cell Biol.. BERLIN: NATURE PORTFOLIO. ISSN 1476-4679

Erkelenz, Steffen ORCID: 0000-0003-4763-1240, Stankovic, Dimitrije, Mundorf, Juliane, Bresser, Tina ORCID: 0000-0002-3827-6403, Claudius, Ann-Katrin, Boehm, Volker ORCID: 0000-0001-7588-9842, Gehring, Niels H. and Uhlirova, Mirka (2021). Ecd promotes U5 snRNP maturation and Prp8 stability. Nucleic Acids Res., 49 (3). S. 1688 - 1708. OXFORD: OXFORD UNIV PRESS. ISSN 1362-4962

Fatscher, Tobias, Boehm, Volker ORCID: 0000-0001-7588-9842 and Gehring, Niels H. ORCID: 0000-0001-7792-1164 (2015). Mechanism, factors, and physiological role of nonsense-mediated mRNA decay. Cell. Mol. Life Sci., 72 (23). S. 4523 - 4545. BASEL: SPRINGER BASEL AG. ISSN 1420-9071

Fatscher, Tobias, Boehm, Volker ORCID: 0000-0001-7588-9842, Weiche, Benjamin and Gehring, Niels H. ORCID: 0000-0001-7792-1164 (2014). The interaction of cytoplasmic poly(A)-binding protein with eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay. RNA, 20 (10). S. 1579 - 1593. COLD SPRING HARBOR: COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT. ISSN 1469-9001

Fatscher, Tobias and Gehring, Niels H. ORCID: 0000-0001-7792-1164 (2016). Harnessing short poly(A)-binding protein-interacting peptides for the suppression of nonsense-mediated mRNA decay. Sci Rep, 6. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

Gehring, Niels H. and Roignant, Jean-Yves (2021). Anything but Ordinary - Emerging Splicing Mechanisms in Eukaryotic Gene Regulation. Trends Genet., 37 (4). S. 355 - 373. LONDON: ELSEVIER SCIENCE LONDON. ISSN 1362-4555

Gehring, Niels H. ORCID: 0000-0001-7792-1164, Wahle, Elmar and Fischer, Utz ORCID: 0000-0002-1465-6591 (2017). Deciphering the mRNP Code: RNA-Bound Determinants of Post-Transcriptional Gene Regulation. Trends Biochem.Sci., 42 (5). S. 369 - 383. LONDON: ELSEVIER SCIENCE LONDON. ISSN 1362-4326

Gerbracht, Jennifer V. ORCID: 0000-0002-3377-4649, Boehm, Volker ORCID: 0000-0001-7588-9842 and Gehring, Niels H. (2017). Plasmid transfection influences the readout of nonsense-mediated mRNA decay reporter assays in human cells. Sci Rep, 7. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

Gerbracht, Jennifer V. ORCID: 0000-0002-3377-4649 and Gehring, Niels H. (2018). The exon junction complex: structural insights into a faithful companion of mammalian mRNPs. Biochem. Soc. Trans., 46. S. 153 - 162. LONDON: PORTLAND PRESS LTD. ISSN 1470-8752

Gerbracht, Jennifer, V, Boehm, Volker, Britto-Borges, Thiago, Kallabis, Sebastian, Wiederstein, Janica L., Ciriello, Simona, Aschemeier, Dominik U., Krueger, Marcus, Frese, Christian K., Altmueller, Janine, Dieterich, Christoph and Gehring, Niels H. ORCID: 0000-0001-7792-1164 (2020). CASC3 promotes transcriptome-wide activation of nonsense-mediated decay by the exon junction complex. Nucleic Acids Res., 48 (15). S. 8626 - 8645. OXFORD: OXFORD UNIV PRESS. ISSN 1362-4962

Gromadzka, Agnieszka M., Steckelberg, Anna-Lena ORCID: 0000-0001-7988-9946, Singh, Kusum K., Hofmann, Kay and Gehring, Niels H. ORCID: 0000-0001-7792-1164 (2016). A short conserved motif in ALYREF directs cap- and EJC-dependent assembly of export complexes on spliced mRNAs. Nucleic Acids Res., 44 (5). S. 2348 - 2362. OXFORD: OXFORD UNIV PRESS. ISSN 1362-4962

Linder, Bastian ORCID: 0000-0003-1203-3136, Fischer, Utz ORCID: 0000-0002-1465-6591 and Gehring, Niels H. ORCID: 0000-0001-7792-1164 (2015). mRNA metabolism and neuronal disease. FEBS Lett., 589 (14). S. 1598 - 1607. HOBOKEN: WILEY. ISSN 1873-3468

Ottens, Franziska ORCID: 0000-0002-0353-2649, Boehm, Volker ORCID: 0000-0001-7588-9842, Sibley, Christopher R., Ule, Jernej ORCID: 0000-0002-2452-4277 and Gehring, Niels H. ORCID: 0000-0001-7792-1164 (2017). Transcript-specific characteristics determine the contribution of endo- and exonucleolytic decay pathways during the degradation of nonsense-mediated decay substrates. RNA, 23 (8). S. 1224 - 1237. COLD SPRING HARBOR: COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT. ISSN 1469-9001

Ottens, Franziska ORCID: 0000-0002-0353-2649 and Gehring, Niels H. ORCID: 0000-0001-7792-1164 (2016). Physiological and pathophysiological role of nonsense-mediated mRNA decay. Pflugers Arch., 468 (6). S. 1013 - 1029. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-2013

Saez, Isabel, Gerbracht, Jennifer, V, Koyuncu, Seda, Lee, Hyun Ju, Horn, Moritz, Kroef, Virginia, Denzel, Martin S., Dieterich, Christoph, Gehring, Niels H. ORCID: 0000-0001-7792-1164 and Vilchez, David ORCID: 0000-0002-0801-0743 (2020). The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells. FEBS Lett., 594 (1). S. 175 - 189. HOBOKEN: WILEY. ISSN 1873-3468

Schlautmann, Lena P. and Gehring, Niels H. ORCID: 0000-0001-7792-1164 (2020). A Day in the Life of the Exon Junction Complex. Biomolecules, 10 (6). BASEL: MDPI. ISSN 2218-273X

Schlautmann, Lena P., Lackmann, Jan-Wilm ORCID: 0000-0001-8182-8034, Altmueller, Janine, Dieterich, Christoph ORCID: 0000-0001-9468-6311, Boehm, Volker ORCID: 0000-0001-7588-9842 and Gehring, Niels H. (2022). Exon junction complex-associated multi-adapter RNPS1 nucleates splicing regulatory complexes to maintain transcriptome surveillance. Nucleic Acids Res., 50 (10). S. 5899 - 5919. OXFORD: OXFORD UNIV PRESS. ISSN 1362-4962

Sriramachandran, Annie M., Meyer-Teschendorf, Katrin, Pabst, Stefan ORCID: 0000-0003-1073-4246, Ulrich, Helle D. ORCID: 0000-0003-0431-2223, Gehring, Niels H., Hofmann, Kay, Praefcke, Gerrit J. K. and Dohmen, R. Jurgen ORCID: 0000-0002-5756-6780 (2019). Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chain. Nat. Commun., 10. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Steckelberg, Anna-Lena ORCID: 0000-0001-7988-9946 and Gehring, Niels H. ORCID: 0000-0001-7792-1164 (2014). Studying the composition of mRNPs in vitro using splicing-competent cell extracts. Methods, 65 (3). S. 342 - 350. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE. ISSN 1095-9130

Voigt, Franka, Gerbracht, Jennifer V. ORCID: 0000-0002-3377-4649, Boehm, Volker ORCID: 0000-0001-7588-9842, Horvathova, Ivana, Eglinger, Jan ORCID: 0000-0001-7234-1435, Chao, Jeffrey A. and Gehring, Niels H. (2019). Detection and quantification of RNA decay intermediates using XRN1-resistant reporter transcripts. Nat. Protoc., 14 (5). S. 1603 - 1634. LONDON: NATURE PUBLISHING GROUP. ISSN 1750-2799

Wallmeroth, Damaris ORCID: 0000-0003-3437-4070, Lackmann, Jan-Wilm ORCID: 0000-0001-8182-8034, Kueckelmann, Sabrina ORCID: 0000-0001-8070-8823, Altmueller, Janine, Dieterich, Christoph ORCID: 0000-0001-9468-6311, Boehm, Volker ORCID: 0000-0001-7588-9842 and Gehring, Niels H. (2022). Human UPF3A and UPF3B enable fault-tolerant activation of nonsense-mediated mRNA decay. Embo J., 41 (10). HOBOKEN: WILEY. ISSN 1460-2075