Universität zu Köln

2022

Overhoff, Melina ORCID: 0000-0002-4208-8632, Tellkamp, Frederik ORCID: 0000-0002-0473-7320, Hess, Simon ORCID: 0000-0001-6085-5156, Tolve, Marianna ORCID: 0000-0002-0893-2967, Tutas, Janine, Faerfers, Marcel, Ickert, Lotte, Mohammadi, Milad ORCID: 0000-0003-1755-108X, De Bruyckere, Elodie, Kallergi, Emmanouela, Delle Vedove, Andrea, Nikoletopoulou, Vassiliki, Wirth, Brunhilde ORCID: 0000-0003-4051-5191, Isensee, Joerg, Hucho, Tim ORCID: 0000-0002-4147-9308, Puchkov, Dmytro, Isbrandt, Dirk ORCID: 0000-0002-4720-1016, Krueger, Marcus, Kloppenburg, Peter and Kononenko, Natalia L. (2022). Autophagy regulates neuronal excitability by controlling cAMP/protein kinase A signaling at the synapse. Embo J., 41 (22). HOBOKEN: WILEY. ISSN 1460-2075

Ratz, Leonie, Brambillasca, Chiara, Bartke, Leandra, Huetzen, Maxim A., Goergens, Jonas, Leidecker, Orsolya, Jachimowicz, Ron D., van de Ven, Marieke, Proost, Natalie, Siteur, Bjorn, de Korte-Grimmerink, Renske, Bouwman, Peter ORCID: 0000-0002-9252-5896, Pulver, Emilia M., de Bruijn, Roebi, Isensee, Joerg, Hucho, Tim ORCID: 0000-0002-4147-9308, Pandey, Gaurav, van Lohuizen, Maarten, Mallmann, Peter, Reinhardt, Hans Christian, Jonkers, Jos ORCID: 0000-0002-9264-9792 and Puppe, Julian (2022). Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer. Breast Cancer Res., 24 (1). LONDON: BMC. ISSN 1465-542X

2021

Isensee, Joerg, van Cann, Marianne, Despang, Patrick ORCID: 0000-0002-5258-3653, Araldi, Dioneia ORCID: 0000-0001-8379-2901, Moeller, Katharina, Petersen, Jonas, Schmidtko, Achim, Matthes, Jan ORCID: 0000-0003-2754-1555, Levine, Jon D. and Hucho, Tim ORCID: 0000-0002-4147-9308 (2021). Depolarization induces nociceptor sensitization by Ca(V)1.2-mediated PKA-II activation. J. Cell Biol., 220 (10). NEW YORK: ROCKEFELLER UNIV PRESS. ISSN 1540-8140

Kanne, Julian, Hussong, Michelle, Isensee, Joerg, Munoz-Lopez, Alvaro, Wolffgramm, Jan, Hess, Felix, Grimm, Christina ORCID: 0000-0002-4676-8870, Bessonov, Sergey, Meder, Lydia, Wang, Jie, Reinhardt, H. Christian, Odenthal, Margarete, Hucho, Tim ORCID: 0000-0002-4147-9308, Buettner, Reinhard, Summerer, Daniel and Schweiger, Michal R. (2021). Pericentromeric Satellite III transcripts induce etoposide resistance. Cell Death Dis., 12 (6). LONDON: SPRINGERNATURE. ISSN 2041-4889

Schmidt, Julia ORCID: 0000-0002-5942-2924, Goergens, Jonas, Pochechueva, Tatiana, Kotter, Annika, Schwenzer, Niko, Sitte, Maren, Werner, Gesa, Altmueller, Janine, Thiele, Holger, Nuernberg, Peter, Isensee, Joerg, Li, Yun, Mueller, Christian, Leube, Barbara, Reinhardt, H. Christian, Hucho, Tim ORCID: 0000-0002-4147-9308, Salinas, Gabriela, Helm, Mark, Jachimowicz, Ron D., Wieczorek, Dagmar, Kohl, Tobias, Lehnart, Stephan E., Yigit, Goekhan and Wollnik, Bernd ORCID: 0000-0003-2589-0364 (2021). Biallelic variants in YRDC cause a developmental disorder with progeroid features. Hum. Genet., 140 (12). S. 1679 - 1694. NEW YORK: SPRINGER. ISSN 1432-1203

2020

Muke, Ines, Isensee, Joerg, Imhof, Thomas, Wiesen, Martin, Wassermann, Meike, Mueller, Carsten, Hucho, Tim, Koch, Manuel and Lehmann, Helmar ORCID: 0000-0001-6205-2293 (2020). New insights into the active transport of paclitaxel into the sensory neuron. J. Peripher. Nerv. Syst., 25 (4). S. 521 - 522. HOBOKEN: WILEY. ISSN 1529-8027

2019

El-Awaad, Ehab, Pryymachuk, Galyna, Fried, Cora, Matthes, Jan ORCID: 0000-0003-2754-1555, Isensee, Joerg, Hucho, Tim, Neiss, Wolfram F., Paulsson, Mats, Herzig, Stefan, Zaucke, Frank and Pietsch, Markus (2019). Direct, gabapentin-insensitive interaction of a soluble form of the calcium channel subunit alpha(2)delta-1 with thrombospondin-4. Sci Rep, 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

Erber, Johanna ORCID: 0000-0001-6614-6051, Steiner, Joachim D., Isensee, Joerg ORCID: 0000-0002-3390-0051, Lobbes, Leonard A., Toschka, Andre, Beleggia, Filippo ORCID: 0000-0003-0234-7094, Schmitt, Anna, Kaiser, Rainer W. J., Siedek, Florian, Persigehl, Thorsten, Hucho, Tim and Reinhardt, Hans C. (2019). Dual Inhibition of GLUT1 and the ATR/CHK1 Kinase Axis Displays Synergistic Cytotoxicity in KRAS-Mutant Cancer Cells. Cancer Res., 79 (19). S. 4855 - 4869. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Jachimowicz, Ron D., Beleggia, Filippo ORCID: 0000-0003-0234-7094, Isensee, Joerg ORCID: 0000-0002-3390-0051, Velpula, Bhagya Bhavana, Goergens, Jonas, Bustos, Matias A., Doll, Markus A., Shenoy, Anjana, Checa-Rodriguez, Cintia, Wiederstein, Janica Lea, Baranes-Bachar, Keren, Bartenhagen, Christoph, Hertwig, Falk ORCID: 0000-0003-4784-6516, Teper, Nizan, Nishi, Tomohiko, Schmitt, Anna, Distelmaier, Felix, Luedecke, Hermann-Josef, Albrecht, Beate, Krueger, Marcus ORCID: 0000-0003-2008-4582, Schumacher, Bjorn ORCID: 0000-0001-6097-5238, Geiger, Tamar, Hoon, Dave S. B., Huertas, Pablo ORCID: 0000-0002-1756-4449, Fischer, Matthias, Hucho, Tim, Peifer, Martin, Ziv, Yael, Reinhardt, H. Christian, Wieczorek, Dagmar and Shiloh, Yosef (2019). UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. Cell, 176 (3). S. 505 - 542. CAMBRIDGE: CELL PRESS. ISSN 1097-4172

2018

Isensee, Joerg ORCID: 0000-0002-3390-0051, Kaufholz, Melanie, Knape, Matthias J., Hasenauer, Jan ORCID: 0000-0002-4935-3312, Hammerich, Hanna, Gonczarowska-Jorge, Humberto, Zahedi, Rene P., Schwede, Frank, Herberg, Friedrich W. and Hucho, Tim ORCID: 0000-0002-4147-9308 (2018). PKA-RII subunit phosphorylation precedes activation by cAMP and regulates activity termination. J. Cell Biol., 217 (6). S. 2167 - 2185. NEW YORK: ROCKEFELLER UNIV PRESS. ISSN 1540-8140

Torgovnick, Alessandro, Heger, Jan Michel, Liaki, Vasiliki, Isensee, Joerg ORCID: 0000-0002-3390-0051, Schmitt, Anna, Knittel, Gero, Riabinska, Arina, Beleggia, Filippo ORCID: 0000-0003-0234-7094, Laurien, Lucie, Leeser, Uschi, Juengst, Christian, Siedek, Florian, Vogel, Wenzel, Kluemper, Niklas, Nolte, Hendrik, Wittersheim, Maike, Tharun, Lars, Castiglione, Roberta ORCID: 0000-0002-9828-4405, Krueger, Marcus, Schauss, Astrid, Perner, Sven, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Buettner, Reinhard, Persigehl, Thorsten, Hucho, Tim, Herter-Sprie, Grit Sophie, Schumacher, Bjoern and Reinhardt, Hans Christian (2018). The Cdkn1a(SuPER) Mouse as a Tool to Study p53-Mediated Tumor Suppression. Cell Reports, 25 (4). S. 1027 - 1046. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

2017

Hussong, Michelle, Kaehler, Christian, Kerick, Martin ORCID: 0000-0002-6298-4514, Grimm, Christina ORCID: 0000-0002-4676-8870, Franz, Alexandra, Timmermann, Bernd, Welzel, Franziska, Isensee, Joerg ORCID: 0000-0002-3390-0051, Hucho, Tim ORCID: 0000-0002-4147-9308, Krobitsch, Sylvia and Schweiger, Michal R. (2017). The bromodomain protein BRD4 regulates splicing during heat shock. Nucleic Acids Res., 45 (1). S. 382 - 395. OXFORD: OXFORD UNIV PRESS. ISSN 1362-4962

Isensee, Joerg ORCID: 0000-0002-3390-0051, Krahe, Leonhardt, Moeller, Katharina, Pereira, Vanessa ORCID: 0000-0001-5416-6856, Sexton, Jane E., Sun, Xiaohui, Emery, Edward ORCID: 0000-0001-9723-8661, Wood, John N. and Hucho, Tim ORCID: 0000-0002-4147-9308 (2017). Synergistic regulation of serotonin and opioid signaling contribute to pain insensitivity in Na(v)1.7 knockout mice. Sci. Signal., 10 (461). WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1937-9145

Isensee, Joerg ORCID: 0000-0002-3390-0051, Schild, Cosimo, Schwede, Frank ORCID: 0000-0002-8185-3392 and Hucho, Tim ORCID: 0000-0002-4147-9308 (2017). Crosstalk from cAMP to ERK1/2 emerges during postnatal maturation of nociceptive neurons and is maintained during aging. J. Cell Sci., 130 (13). S. 2134 - 2147. CAMBRIDGE: COMPANY BIOLOGISTS LTD. ISSN 1477-9137

Lechner, Axel, Schloesser, Hans, Rothschild, Sacha I., Thelen, Martin ORCID: 0000-0002-2785-9726, Reuter, Sabrina, Zentis, Peter, Shimabukuro-Vornhagen, Alexander, Theurich, Sebastian ORCID: 0000-0001-5706-8258, Wennhold, Kerstin ORCID: 0000-0001-5539-7226, Garcia-Marquez, Maria, Tharun, Lars, Quaas, Alexander, Schauss, Astrid, Isensee, Joerg ORCID: 0000-0002-3390-0051, Hucho, Tim ORCID: 0000-0002-4147-9308, Huebbers, Christian ORCID: 0000-0002-2934-1218, von Bergwelt-Baildon, Michael and Beutner, Dirk (2017). Characterization of tumor-associated T-lymphocyte subsets and immune checkpoint molecules in head and neck squamous cell carcinoma. Oncotarget, 8 (27). S. 44418 - 44434. ORCHARD PARK: IMPACT JOURNALS LLC. ISSN 1949-2553

2014

Isensee, Joerg ORCID: 0000-0002-3390-0051, Diskar, Mandy, Waldherr, Steffen ORCID: 0000-0002-0936-579X, Buschow, Rene ORCID: 0000-0002-9800-2578, Hasenauer, Jan ORCID: 0000-0002-4935-3312, Prinz, Anke, Allgoewer, Frank, Herberg, Friedrich W. and Hucho, Tim ORCID: 0000-0002-4147-9308 (2014). Pain modulators regulate the dynamics of PKA-RII phosphorylation in subgroups of sensory neurons. J. Cell Sci., 127 (1). S. 216 - 230. CAMBRIDGE: COMPANY OF BIOLOGISTS LTD. ISSN 1477-9137

Isensee, Joerg ORCID: 0000-0002-3390-0051, Wenzel, Carsten, Buschow, Rene ORCID: 0000-0002-9800-2578, Weissmann, Robert, Kuss, Andreas W. and Hucho, Tim ORCID: 0000-0002-4147-9308 (2014). Subgroup-Elimination Transcriptomics Identifies Signaling Proteins that Define Subclasses of TRPV1-Positive Neurons and a Novel Paracrine Circuit. PLoS One, 9 (12). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

Kaehler, Christian, Isensee, Joerg ORCID: 0000-0002-3390-0051, Hucho, Tim ORCID: 0000-0002-4147-9308, Lehrach, Hans and Krobitsch, Sylvia (2014). 5-Fluorouracil affects assembly of stress granules based on RNA incorporation. Nucleic Acids Res., 42 (10). S. 6436 - 6448. OXFORD: OXFORD UNIV PRESS. ISSN 1362-4962

2013

Andres, Christine, Hasenauer, Jan ORCID: 0000-0002-4935-3312, Ahn, Hye-Sook, Joseph, Elizabeth K., Isensee, Joerg ORCID: 0000-0002-3390-0051, Theis, Fabian J., Allgoewer, Frank, Levine, Jon D., Dib-Hajj, Sulayman D., Waxman, Stephen G. and Hucho, Tim ORCID: 0000-0002-4147-9308 (2013). Wound-healing growth factor, basic FGF, induces Erk1/2-dependent mechanical hyperalgesia. Pain, 154 (10). S. 2216 - 2227. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1872-6623

2012

Kaehler, Christian, Isensee, Joerg ORCID: 0000-0002-3390-0051, Nonhoff, Ute, Terrey, Markus ORCID: 0000-0002-7359-4810, Hucho, Tim ORCID: 0000-0002-4147-9308, Lehrach, Hans and Krobitsch, Sylvia (2012). Ataxin-2-Like Is a Regulator of Stress Granules and Processing Bodies. PLoS One, 7 (11). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203