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Journal Article
Becker, Christian, Oecal, Sinan, Nguyen, Hoang D., Keul, Marina, Simard, Jeffrey R. and Rauh, Daniel 
ORCID: 0000-0002-1970-7642
(2016).
Monitoring Conformational Changes in the Receptor Tyrosine Kinase EGFR.
ChemBioChem, 17 (11).
S. 990 - 995.
WEINHEIM:
WILEY-V C H VERLAG GMBH.
ISSN 1439-7633
Engel, Julian, Richters, Andre, Getlik, Matthaeus, Tomassi, Stefano, Keul, Marina, Termathe, Martin ORCID: 0000-0002-5618-4633, Lategahn, Jonas ORCID: 0000-0001-5993-7082, Becker, Christian, Mayer-Wrangowski, Svenja, Gruetter, Christian, Uhlenbrock, Niklas ORCID: 0000-0002-4489-9535, Kruell, Jasmin, Schaumann, Niklas, Eppmann, Simone, Kibies, Patrick, Hoffgaard, Franziska, Heil, Jochen, Menninger, Sascha, Ortiz-Cuaran, Sandra, Heuckmann, Johannes M., Tinnefeld, Verena, Zahedi, Rene P., Sos, Martin L., Schultz-Fademrecht, Carsten, Thomas, Roman K., Kast, Stefan M. and Rauh, Daniel ORCID: 0000-0002-1970-7642
(2015).
Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach.
J. Med. Chem., 58 (17).
S. 6844 - 6864.
WASHINGTON:
AMER CHEMICAL SOC.
ISSN 1520-4804
Engel, Julian, Smith, Steven, Lategahn, Jonas ORCID: 0000-0001-5993-7082, Turnbrink, Hannah L., Goebel, Lisa, Becker, Christian, Hennes, Elisabeth, Keul, Marina, Unger, Anke, Mueller, Heiko, Baumann, Matthias, Schultz-Fademrecht, Carsten, Guenther, Georgia, Hengstler, Jan G. and Rauh, Daniel
(2017).
Structure-Guided Development of Covalent and Mutant-Selective Pyrazolopyrimidines to Target T790M Drug Resistance in Epidermal Growth Factor Receptor.
J. Med. Chem., 60 (18).
S. 7725 - 7745.
WASHINGTON:
AMER CHEMICAL SOC.
ISSN 1520-4804
Fassunke, Jana, Mueller, Fabienne, Keul, Marina, Michels, Sebastian, Dammert, Marcel A., Schmitt, Anna, Plenker, Dennis, Lategahn, Jonas ORCID: 0000-0001-5993-7082, Heydt, Carina, Braegelmann, Johannes, Tumbrink, Hannah L., Alber, Yannic, Klein, Sebastian, Heimsoeth, Alena, Dahmen, Ilona, Fischers, Rieke N., Scheffler, Matthias, Ihle, Michaela A., Priesner, Vanessa, Scheel, Andreas H., Wagener, Svenja, Kron, Anna, Frank, Konrad, Garbert, Katia, Persigehl, Thorsten, Puesken, Michael, Haneder, Stefan, Schaaf, Bernhard, Rodermann, Ernst, Engel-Riedel, Walburga, Felip, Enriqueta, Smit, Egbert F., Merkelbach-Bruse, Sabine, Reinhardt, H. Christian, Kast, Stefan M., Wolf, Juergen, Rauh, Daniel, Buettner, Reinhard and Sos, Martin L.
(2018).
Overcoming EGFR(G724S)-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors.
Nat. Commun., 9.
LONDON:
NATURE PUBLISHING GROUP.
ISSN 2041-1723
Lategahn, Jonas ORCID: 0000-0001-5993-7082, Keul, Marina, Kloevekorn, Philip, Tumbrink, Hannah L., Niggenaber, Janina ORCID: 0000-0003-2942-263X, Mueller, Matthias P., Hodson, Luke, Flasshoff, Maren, Hardick, Julia, Grabe, Tobias, Engel, Julian, Schultz-Fademrecht, Carsten, Baumann, Matthias, Ketzer, Julia, Muehlenberg, Thomas, Hiller, Wolf, Guenther, Georgia, Unger, Anke, Mueller, Heiko, Heimsoeth, Alena, Golz, Christopher, Blank-Landeshammer, Bernhard, Kollipara, Laxmikanth, Zahedi, Rene P., Strohmann, Carsten ORCID: 0000-0002-4787-2135, Hengstler, Jan G., van Otterlo, Willem A. L., Bauer, Sebastian ORCID: 0000-0001-5949-8120 and Rauh, Daniel
(2019).
Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S.
Chem. Sci., 10 (46).
S. 10789 - 10802.
CAMBRIDGE:
ROYAL SOC CHEMISTRY.
ISSN 2041-6539
Lategahn, Jonas, Tumbrink, Hannah L., Schultz-Fademrecht, Carsten, Heimsoeth, Alena, Werr, Lisa ORCID: 0000-0002-3697-4136, Niggenaber, Janina, Keul, Marina, Parmaksiz, Fatma ORCID: 0009-0003-3771-7128, Baumann, Matthias, Menninger, Sascha, Zent, Eldar, Landel, Ina, Weisner, Joern, Jeyakumar, Kirujan ORCID: 0000-0002-0184-6775, Heyden, Leonie, Russ, Nicole, Mueller, Fabienne, Lorenz, Carina, Braegelmann, Johannes, Spille, Inga, Grabe, Tobias ORCID: 0000-0002-8287-1971, Mueller, Matthias P., Heuckmann, Johannes M., Klebl, Bert M., Nussbaumer, Peter, Sos, Martin L. and Rauh, Daniel
(2022).
Insight into Targeting Exon20 Insertion Mutations of the Epidermal Growth Factor Receptor with Wild Type-Sparing Inhibitors.
J. Med. Chem., 65 (9).
S. 6643 - 6656.
WASHINGTON:
AMER CHEMICAL SOC.
ISSN 1520-4804
Plenker, Dennis, Riedel, Maximilian, Braegelmann, Johannes, Dammert, Marcel A., Chauhan, Rakhee, Knowles, Phillip P., Lorenz, Carina, Keul, Marina, Buehrmann, Mike, Pagel, Oliver, Tischler, Verena ORCID: 0000-0002-6673-8329, Scheel, Andreas H., Schtte, Daniel, Song, Yanrui, Stark, Justina, Mrugalla, Florian ORCID: 0000-0002-6281-6051, Alber, Yannic, Richters, Andre, Engel, Julian, Leenders, Frauke, Heuckmann, Johannes M., Wolf, Juergen, Diebold, Joachim, Pall, Georg, Peifer, Martin ORCID: 0000-0002-5243-5503, Aerts, Maarten, Gevaert, Kris ORCID: 0000-0002-4237-0283, Zahedi, Rene P., Buettner, Reinhard, Shokat, Kevan M., McDonald, Neil Q., Kast, Stefan M., Gautschi, Oliver, Thomas, Roman K. and Sos, Martin L.
(2017).
Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors.
Sci. Transl. Med., 9 (394).
WASHINGTON:
AMER ASSOC ADVANCEMENT SCIENCE.
ISSN 1946-6242