Universität zu Köln

Journal Article

Dietlein, Felix, Thelen, Lisa, Jokic, Mladen, Jachimowicz, Ron D., Ivan, Laura, Knittel, Gero, Leeser, Uschi, van Oers, Johanna, Edelmann, Winfried, Heukamp, Lukas C. and Reinhardt, H. Christian (2014). A Functional Cancer Genomics Screen Identifies a Druggable Synthetic Lethal Interaction between MSH3 and PRKDC. Cancer Discov., 4 (5). S. 592 - 606. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 2159-8290

Fluemann, Ruth, Hansen, Julia, Pelzer, Benedikt, Kiss, Ilmars, Lohmann, Tim, Persigehl, Thorsten, Abedpour, Nima, Peifer, Martin, Buettner, Reinhard, von Tresckow, Bastian, Jachimowicz, Ron, Reinhardt, Hans Christian and Knittel, Gero (2022). Novel Autochthonous Mouse Models of Serve As Preclinical Tools to Investigate Pathogenesis and Treatment of MCD/C5 DLBCL. Blood, 140. S. 3493 - 3495. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Fluemann, Ruth, Nieper, Pascal, Reinhardt, Hans Christian and Knittel, Gero (2020). New murine models of aggressive lymphoma. Leuk. Lymphoma, 61 (4). S. 788 - 799. ABINGDON: TAYLOR & FRANCIS LTD. ISSN 1029-2403

Fluemann, Ruth, Rehkaemper, Tim, Nieper, Pascal, Pfeiffer, Pauline, Holzem, Alessandra, Klein, Sebastian ORCID: 0000-0002-2188-9377, Bhatia, Sanil ORCID: 0000-0001-6494-7744, Kochanek, Moritz, Kisis, Ilmars ORCID: 0000-0001-6207-3991, Pelzer, Benedikt W., Ahlert, Heinz, Hauer, Julia, Guerreiro, Alexandra da Palma, Ryan, Jeremy A., Reimann, Maurice, Riabinska, Arina, Wiederstein, Janica, Krueger, Marcus, Deckert, Martina, Altmueller, Janine, Klatt, Andreas R., Frenzel, Lukas P., Pasqualucci, Laura, Beguelin, Wendy, Melnick, Ari M., Sander, Sandrine, Montesinos-Rongen, Manuel ORCID: 0000-0003-4724-5526, Brunn, Anna, Lohneis, Philipp, Buettner, Reinhard, Kashkar, Hamid, Borkhardt, Arndt, Letai, Anthony, Persigehl, Thorsten, Peifer, Martin, Schmitt, Clemens A. ORCID: 0000-0002-4731-2226, Reinhardt, Hans Christian and Knittel, Gero ORCID: 0000-0001-8395-3701 (2021). An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities. Blood Cancer Discov., 2 (1). S. 70 - 92. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 2643-3249

Guerreiro, Alexandra da Palma, Dorweiler, Cornelia, Halmer, Ismini, Merkel, Olaf, Hartmann, Elena Maria, Berg, Valeska, Reinart, Nina, Fingerle-Rowson, Guenter, Knittel, Gero, Pallasch, Christian, Rosenwald, Andreas, Reinhardt, Christian, Wendtner, Clemens-Martin, Hallek, Michael and Frenzel, Lukas P. (2018). FcmR Shapes BCR Signaling in IgM-Positive Leukemia. Blood, 132. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Guerreiro, Alexandra da Palma, Dorweiler, Cornelia, Kintzele, Laurent, Baatout, Dunja, Huelsemann, Malte, Berg, Valeska, Merkel, Olaf, Reinart, Nina, Fingerle-Rowson, Guenter, Knittel, Gero, Pallasch, Christian, Reinhardt, Hans Christian, Wendtner, Clemens Martin, Hallek, Michael and Frenzel, Lukas P. (2016). Loss of TOSO Promotes Richter's Transformation of TCL1A Driven CLL. Blood, 128 (22). WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Izquierdo, Elena, Vorholt, Daniela, Blakemore, Stuart, Sackey, Benedict ORCID: 0000-0003-1016-7720, Nolte, Janica L., Barbarino, Verena, Schmitz, Jan, Nickel, Nadine, Bachurski, Daniel ORCID: 0000-0001-9168-9680, Lobastova, Liudmila, Nikolic, Milos, Michalik, Michael, Brinker, Reinhild, Merkel, Olaf, Franitza, Marek, Georgomanolis, Theodoros, Neuhaus, Rene, Koch, Maximilian, Nasada, Niklas, Knittel, Gero, Chapuy, Bjoern ORCID: 0000-0002-6485-8773, Ludwig, Nicole, Meese, Eckart, Frenzel, Lukas, Reinhardt, Hans Christian, Peifer, Martin ORCID: 0000-0002-5243-5503, Rebollido-Rios, Rocio, Bruns, Heiko, Krueger, Marcus, Hallek, Michael and Pallasch, Christian P. (2022). Extracellular vesicles and PD-L1 suppress macrophages, inducing therapy resistance in TP53-deficient B-cell malignancies. Blood, 139 (25). S. 3617 - 3630. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Knittel, Gero, Liedgens, Paul, Fritz, Christian, Korovkina, Darya, Huelsemann, Malte, Al-Baldawi, Yussor, Persigehl, Thorsten, Frenzel, Lukas and Reinhardt, Christian (2015). Establishment of a pre-clinical in vivo platform spanning low-risk to high-risk CLL. Leuk. Lymphoma, 56. S. 114 - 116. ABINGDON: TAYLOR & FRANCIS LTD. ISSN 1029-2403

Knittel, Gero, Liedgens, Paul, Korovkina, Darya, Pallasch, Christian P. ORCID: 0000-0001-5675-6905 and Reinhardt, Hans Christian (2016). Rewired NF kappa B signaling as a potentially actionable feature of activated B-cell-like diffuse large B-cell lymphoma. Eur. J. Haematol., 97 (6). S. 499 - 511. HOBOKEN: WILEY-BLACKWELL. ISSN 1600-0609

Knittel, Gero, Liedgens, Paul, Korovkina, Darya, Seeger, Jens M., Al-Baldawi, Yussor, Al-Maarri, Mona, Fritz, Christian, Vlantis, Katerina, Bezhanova, Svetlana ORCID: 0000-0001-7336-9210, Scheel, Andreas H., Wolz, Olaf-Oliver, Reimann, Maurice, Moeller, Peter, Lopez, Cristina ORCID: 0000-0001-6644-1659, Schlesner, Matthias ORCID: 0000-0002-5896-4086, Lohneis, Philipp, Weber, Alexander N. R., Truemper, Lorenz, Staudt, Louis M., Ortmann, Monika, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Siebert, Reiner, Schmitt, Clemens A., Klatt, Andreas R., Wunderlich, F. Thomas, Schaefer, Stephan C., Persigehl, Thorsten, Montesinos-Rongen, Manuel, Odenthal, Margarete, Buettner, Reinhard, Frenzel, Lukas P., Kashkar, Hamid and Reinhardt, H. Christian (2016). B-cell-specific conditional expression of Myd88(p.L252P) leads to the development of diffuse large B-cell lymphoma in mice. Blood, 127 (22). S. 2732 - 2742. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Knittel, Gero, Liedgens, Paul and Reinhardt, Hans C. (2015). Targeting ATM-deficient CLL through interference with DNA repair pathways. Front. Genet., 6. LAUSANNE: FRONTIERS MEDIA SA. ISSN 1664-8021

Knittel, Gero, Rehkaemper, Tim, Korovkina, Darya, Liedgens, Paul, Fritz, Christian, Torgovnick, Alessandro, Al-Baldawi, Yussor, Al-Maarri, Mona, Cun, Yupeng ORCID: 0000-0002-4241-8099, Fedorchenko, Oleg, Riabinska, Arina, Beleggia, Filippo ORCID: 0000-0003-0234-7094, Wunderlich, F. Thomas, Ortmann, Monika, Montesinos-Rongen, Manuel, Tausch, Eugen, Stilgenbauer, Stephan, Frenzel, Lukas P., Herling, Marco, Herling, Carmen, Bahlo, Jasmin, Hallek, Michael, Peifer, Martin ORCID: 0000-0002-5243-5503, Buettner, Reinhard, Persigehl, Thorsten and Reinhardt, H. Christian (2017). Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia. Nat. Commun., 8. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Knittel, Gero, Rehkaemper, Tim, Nieper, Pascal, Schmitt, Anna, Fluemann, Ruth and Reinhardt, H. Christian (2018). DNA damage pathways and B-cell lymphomagenesis. Curr. Opin. Hematol., 25 (4). S. 315 - 323. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1531-7048

Koch, Maximilian, Reinartz, Sebastian, Saggau, Julia, Knittel, Gero, Rosen, Natascha, Fedorchenko, Oleg, Thelen, Lisa, Barthel, Romy, Reinart, Nina, Seeger-Nukpezah, Tamina, Reinhardt, Hans Christian, Hallek, Michael and Nguyen, Phuong-Hien (2020). Meta-Analysis Reveals Significant Sex Differences in Chronic Lymphocytic Leukemia Progression in theE mu-TCL1Transgenic Mouse Model. Cancers, 12 (7). BASEL: MDPI. ISSN 2072-6694

Nickel, Nadine, Al-Maarri, Mona, Pal, Martin, Roth, Andreas, Knittel, Gero, Herling, Carmen D., Reinart, Nina, Schafer, Stephan, Hartmann, Elena M., Rosenwald, Andreas, Klapper, Wolfram, Buttner, Reinhard, Herling, Marco, Bruening, Jens, Reinhardt, Christian, Hallek, Michael, Wunderlich, Thomas and Pallasch, Christian (2016). Transformation of Chronic Lymphocytic Leukemia Towards Richter's Syndrome Is Induced By AKT Activation. Blood, 128 (22). WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Pindzola, Grace M., Razzaghi, Raud ORCID: 0000-0002-6410-9932, Tavory, Rachel N., Nguyen, Hang T., Morris, Vivian M., Li, Moyi, Agarwal, Shreya, Huang, Bonnie, Okada, Takaharu, Reinhardt, Hans C., Knittel, Gero, Kashkar, Hamid, Young, Ryan M., Pittaluga, Stefania and Muppidi, Jagan R. (2022). Aberrant expansion of spontaneous splenic germinal centers induced by hallmark genetic lesions of aggressive lymphoma. Blood, 140 (10). S. 1119 - 1132. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Reimann, Maurice, Schrezenmeier, Jens, Richter-Pechanska, Paulina, Dolnik, Anna, Hick, Timon Pablo, Schleich, Kolja, Cai, Xiurong, Fan, Dorothy N. Y., Lohneis, Philipp, Masswig, Sven, Denker, Sophy ORCID: 0000-0002-0736-6019, Busse, Antonia ORCID: 0000-0002-3470-6947, Knittel, Gero ORCID: 0000-0001-8395-3701, Flumann, Ruth, Childs, Dorothee, Childs, Liam ORCID: 0000-0002-2080-1804, Gaetjens-Sanchez, Ana-Maria, Bullinger, Lars ORCID: 0000-0002-5890-5510, Rosenwald, Andreas, Reinhardt, Hans Christian and Schmitt, Clemens A. ORCID: 0000-0002-4731-2226 (2021). Adaptive T-cell immunity controls senescence-prone MyD88-or CARD11-mutant B-cell lymphomas. Blood, 137 (20). S. 2785 - 2800. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Schmitt, Anna, Knittel, Gero, Welcker, Daniela, Yang, Tsun-Po ORCID: 0000-0002-9077-4434, George, Julie, Nowak, Michael, Leeser, Uschi, Buettner, Reinhard, Perner, Sven, Peifer, Martin ORCID: 0000-0002-5243-5503 and Reinhardt, Hans Christian (2017). ATM Deficiency Is Associated with Sensitivity to PARP1-and ATR Inhibitors in Lung Adenocarcinoma. Cancer Res., 77 (11). S. 3040 - 3057. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Schuldner, Maximiliane, Doersam, Bastian, Shatnyeva, Olga, Reiners, Katrin S., Kubarenko, Andriy, Hansen, Hinrich P., Finkernagel, Florian, Roth, Katrin, Theurich, Sebastian ORCID: 0000-0001-5706-8258, Nist, Andrea, Stiewe, Thorsten ORCID: 0000-0003-0134-7826, Paschen, Annette, Knittel, Gero, Reinhardt, Hans C., Mueller, Rolf, Hallek, Michael and von Strandmann, Elke Pogge (2019). Exosome-dependent immune surveillance at the metastatic niche requires BAG6 and CBP/p300-dependent acetylation of p53. Theranostics, 9 (21). S. 6047 - 6063. LAKE HAVEN: IVYSPRING INT PUBL. ISSN 1838-7640

Torgovnick, Alessandro, Heger, Jan Michel, Liaki, Vasiliki, Isensee, Joerg ORCID: 0000-0002-3390-0051, Schmitt, Anna, Knittel, Gero, Riabinska, Arina, Beleggia, Filippo ORCID: 0000-0003-0234-7094, Laurien, Lucie, Leeser, Uschi, Juengst, Christian, Siedek, Florian, Vogel, Wenzel, Kluemper, Niklas, Nolte, Hendrik, Wittersheim, Maike, Tharun, Lars, Castiglione, Roberta ORCID: 0000-0002-9828-4405, Krueger, Marcus, Schauss, Astrid, Perner, Sven, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Buettner, Reinhard, Persigehl, Thorsten, Hucho, Tim, Herter-Sprie, Grit Sophie, Schumacher, Bjoern and Reinhardt, Hans Christian (2018). The Cdkn1a(SuPER) Mouse as a Tool to Study p53-Mediated Tumor Suppression. Cell Reports, 25 (4). S. 1027 - 1046. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

Vorholt, Daniela, Izquierdo-Alvarez, Elena, Sackey, Benedict, Schmitz, Jan, Nickel, Nadine, Blakemore, Stuart, Knittel, Gero, Reinhardt, Christian, Wendtner, Clemens-Martin, Bruns, Heiko, Hallek, Michael and Pallasch, Christian (2018). DNA Damage-Response Pathway in Lymphoma Determines Interactions with Macrophages By Altered PD-Li Expression and Fxosome Formation. Blood, 132. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020