Universität zu Köln

Journal Article

Fang, Zhizhou, Simard, Jeffrey R., Plenker, Dennis, Nguyen, Hoang D., Wolle, Patrik, Baumeister, Stefan and Rauh, Daniel ORCID: 0000-0002-1970-7642 (2015). Discovery of Inter-Domain Stabilizers-A Novel Assay System for Allosteric Akt Inhibitors. ACS Chem. Biol., 10 (1). S. 279 - 289. WASHINGTON: AMER CHEMICAL SOC. ISSN 1554-8937

Fassunke, Jana, Mueller, Fabienne, Keul, Marina, Michels, Sebastian, Dammert, Marcel A., Schmitt, Anna, Plenker, Dennis, Lategahn, Jonas ORCID: 0000-0001-5993-7082, Heydt, Carina, Braegelmann, Johannes, Tumbrink, Hannah L., Alber, Yannic, Klein, Sebastian, Heimsoeth, Alena, Dahmen, Ilona, Fischers, Rieke N., Scheffler, Matthias, Ihle, Michaela A., Priesner, Vanessa, Scheel, Andreas H., Wagener, Svenja, Kron, Anna, Frank, Konrad, Garbert, Katia, Persigehl, Thorsten, Puesken, Michael, Haneder, Stefan, Schaaf, Bernhard, Rodermann, Ernst, Engel-Riedel, Walburga, Felip, Enriqueta, Smit, Egbert F., Merkelbach-Bruse, Sabine, Reinhardt, H. Christian, Kast, Stefan M., Wolf, Juergen, Rauh, Daniel, Buettner, Reinhard and Sos, Martin L. (2018). Overcoming EGFR(G724S)-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors. Nat. Commun., 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Fernandez-Cuesta, Lynnette ORCID: 0000-0002-0724-6703, Plenker, Dennis, Osada, Hirotaka, Sun, Ruping, Menon, Roopika, Leenders, Frauke, Ortiz-Cuaran, Sandra, Peifer, Martin ORCID: 0000-0002-5243-5503, Bos, Marc, Dassler, Juliane, Malchers, Florian, Schottle, Jakob, Vogel, Wenzel, Dahmen, Ilona, Koker, Mirjam, Ullrich, Roland T., Wright, Gavin M., Russell, Prudence A., Wainer, Zoe, Solomon, Benjamin, Brambilla, Elisabeth, Nagy-Mignotte, Helene, Moro-Sibilot, Denis, Brambilla, Christian G., Lantuejoul, Sylvie, Altmuller, Janine, Becker, Christian, Nurnberg, Peter, Heuckmann, Johannes M., Stoelben, Erich, Petersen, Iver, Clement, Joachim H. ORCID: 0000-0002-6601-2456, Saenger, Joerg, Muscarella, Lucia A., la Torre, Annamaria ORCID: 0000-0003-4199-1077, Fazio, Vito M., Lahortiga, Idoya, Perera, Timothy, Ogata, Souichi, Parade, Marc, Brehmer, Dirk, Vingron, Martin, Heukamp, Lukas C., Buettner, Reinhard, Zander, Thomas, Wolf, Jurgen, Perner, Sven, Ansen, Sascha, Haas, Stefan A., Yatabe, Yasushi ORCID: 0000-0003-1788-559X and Thomas, Roman K. (2014). CD74-NRG1 Fusions in Lung Adenocarcinoma. Cancer Discov., 4 (4). S. 415 - 423. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 2159-8290

Fernandez-Cuesta, Lynnette ORCID: 0000-0002-0724-6703, Sun, Ruping, Menon, Roopika, George, Julie, Lorenz, Susanne, Meza-Zepeda, Leonardo A., Peifer, Martin ORCID: 0000-0002-5243-5503, Plenker, Dennis, Heuckmann, Johannes M., Leenders, Frauke, Zander, Thomas, Dahmen, Ilona, Koker, Mirjam, Schoettle, Jakob, Ullrich, Roland T., Altmueller, Janine, Becker, Christian, Nuernberg, Peter, Seidel, Henrik ORCID: 0000-0001-7804-5143, Boehm, Diana, Goeke, Friederike, Ansen, Sascha, Russell, Prudence A., Wright, Gavin M., Wainer, Zoe, Solomon, Benjamin, Petersen, Iver, Clement, Joachim H. ORCID: 0000-0002-6601-2456, Saenger, Joerg, Brustugun, Odd-Terje, Helland, Aslaug ORCID: 0000-0002-5520-0275, Solberg, Steinar, Lund-Iversen, Marius, Buettner, Reinhard, Wolf, Juergen, Brambilla, Elisabeth, Vingron, Martin, Perner, Sven, Haas, Stefan A. and Thomas, Roman K. (2015). Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data. Genome Biol., 16. LONDON: BIOMED CENTRAL LTD. ISSN 1474-760X

Malchers, Florian, Dietlein, Felix, Schottle, Jakob, Lu, Xin, Nogova, Lucia, Albus, Kerstin, Fernandez-Cuesta, Lynnette ORCID: 0000-0002-0724-6703, Heuckmann, Johannes M., Gautschi, Oliver, Diebold, Joachim, Plenker, Dennis, Gardizi, Masyar, Er, Matthias Scheffl, Bos, Marc, Seidel, Danila, Leenders, Frauke, Richters, Andre, Peifer, Martin ORCID: 0000-0002-5243-5503, Florin, Alexandra, Mainkar, Prathama S., Karre, Nagaraju, Chandrasekhar, Srivari, George, Julie, Silling, Steffi, Rauh, Daniel ORCID: 0000-0002-1970-7642, Zander, Thomas, Ullrich, Roland T., Reinhardt, H. Christian, Ringeisen, Francois, Buettner, Reinhard, Heukamp, Lukas C., Wolf, Juergen and Thomas, Roman K. (2014). Cell-Autonomous and Non-Cell-Autonomous Mechanisms of Transformation by Amplified FGFR1 in Lung Cancer. Cancer Discov., 4 (2). S. 246 - 258. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 2159-8290

Merk, Daniel J., Ohli, Jasmin, Merk, Natalie D., Thatikonda, Venu, Morrissy, Sorana ORCID: 0000-0001-8526-562X, Schoof, Melanie, Schmid, Susanne N., Harrison, Luke, Filser, Severin, Ahlfeld, Julia ORCID: 0000-0002-4879-4159, Erkek, Serap ORCID: 0000-0003-4439-5203, Raithatha, Kaamini, Andreska, Thomas, Weisshaar, Marc, Launspach, Michael, Neumann, Julia E., Shakarami, Mehdi, Plenker, Dennis, Marra, Marco A., Li, Yisu, Mungall, Andrew J. ORCID: 0000-0002-0905-2742, Moore, Richard A., Ma, Yussanne, Jones, Steven J. M., Lutz, Beat, Ertl-Wagner, Birgit, Rossi, Andrea ORCID: 0000-0001-8575-700X, Wagener, Rabea, Siebert, Reiner, Jung, Andreas, Eberhart, Charles G., Lach, Boleslaw, Sendtner, Michael, Pfister, Stefan M., Taylor, Michael D., Chavez, Lukas ORCID: 0000-0002-8718-8848, Kool, Marcel and Schueller, Ulrich (2018). Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma. Dev. Cell, 44 (6). S. 709 - 731. CAMBRIDGE: CELL PRESS. ISSN 1878-1551

Michels, Sebastian, Heydt, Carina, van Veggel, Bianca, Deschler-Baier, Barbara, Pardo, Nuria, Monkhorst, Kim, Ruesseler, Vanessa, Stratmann, Jan, Griesinger, Frank, Steinhauser, Susanne, Kostenko, Anna, Diebold, Joachim, Fassunke, Jana, Fischer, Rieke, Engel-Riedel, Walburga, Gautschi, Oliver, Geissinger, Eva, Haneder, Stefan, Ihle, Michaela A., Kopp, Hans-Georg, de Langen, Adrianus J., Martinez-Marti, Alex, Nogova, Lucia, Persigehl, Thorsten, Plenker, Dennis, Puesken, Michael, Rodermann, Ernst, Rosenwald, Andreas, Scheel, Andreas H., Scheffler, Matthias, Spengler, Werner, Seggewiss-Bernhardt, Ruth, Braegelmann, Johannes, Sebastian, Martin, Vrugt, Bart, Hellmich, Martin, Sos, Martin L., Heukamp, Lukas C., Felip, Enriqueta, Merkelbach-Bruse, Sabine, Smit, Egbert F., Buettner, Reinhard and Wolf, Juergen (2019). Genomic Profiling Identifies Outcome-Relevant Mechanisms of Innate and Acquired Resistance to Third-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy in Lung Cancer. JCO Precis. Oncol., 3. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. ISSN 2473-4284

Michels, Sebastian, Scheffler, Matthias, Wagener, Svenja, Plenker, Dennis, Scheel, Andreas, Nogova, Lucia, Schultheis, Anne, Fischer, Rieke N., Abdulla, Diana S. Y., Riedel, Richard, Bunck, Anne, Kobe, Carsten, Baus, Wolfgang, Merkelbach-Bruse, Sabine, Sos, Martin L., Buttner, Reinhard and Wolf, Jurgen (2018). Loss of G2032R Resistance Mutation Upon Chemotherapy Treatment Enables Successful Crizotinib Rechallenge in a Patient With ROS1-Rearranged NSCLC. JCO Precis. Oncol., 2. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. ISSN 2473-4284

Ortiz-Cuaran, Sandra, Scheffler, Matthias ORCID: 0000-0002-9031-1368, Plenker, Dennis, Dahmen, Ilona, Scheel, Andreas H., Fernandez-Cuesta, Lynnette ORCID: 0000-0002-0724-6703, Meder, Lydia ORCID: 0000-0002-9547-5812, Lovly, Christine M., Persigehl, Thorsten, Merkelbach-Bruse, Sabine, Bos, Marc, Michels, Sebastian, Fischer, Rieke, Albus, Kerstin, Koenig, Katharina, Schildhaus, Hans-Ulrich, Fassunke, Jana, Ihle, Michaela A., PasternackO, Helen, Heydt, Carina, Becker, Christian, Altmueller, Janine, Ji, Hongbin, Mueller, Christian, Florin, Alexandra, Heuckmann, Johannes M., Nuernberg, Peter, Ansen, Sascha, Heukamp, Lukas C., Berg, Johannes, Pao, William, Peifer, Martin ORCID: 0000-0002-5243-5503, Buettner, Reinhard, Wolfe, Juergen, Thomas, Roman K. and Sos, Martin L. (2016). Heterogeneous Mechanisms of Primary and Acquired Resistance to Third-Generation EGFR Inhibitors. Clin. Cancer Res., 22 (19). S. 4837 - 4848. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Plenker, Dennis, Bertrand, Miriam, de Langen, Adrianus J., Riedel, Richard, Lorenz, Carina, Scheel, Andreas H., Mueller, Judith, Braegelmann, Johannes, Dassler-Plenker, Juliane, Kobe, Carsten, Persigehl, Thorsten, Kluge, Alexander, Wurdinger, Thomas, Schellen, Pepijn, Hartmann, Gunther ORCID: 0000-0003-1021-2018, Zacherle, Tobias, Menon, Roopika, Thunnissen, Erik, Buettner, Reinhard, Griesinger, Frank, Wolf, Juergen, Heukamp, Lukas ORCID: 0000-0002-3388-3482, Sos, Martin L. and Heuckmann, Johannes M. (2018). Structural Alterations of MET Trigger Response to MET Kinase Inhibition in Lung Adenocarcinoma Patients. Clin. Cancer Res., 24 (6). S. 1337 - 1344. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Plenker, Dennis, Fernandez-Cuesta, Lynnette ORCID: 0000-0002-0724-6703, Osada, Hirotaka, Sun, Ruping, Bos, Marc, Dassler, Juliane, Wright, Gavin, Brambilla, Elisabeth, Buettner, Reinhard, Ansen, Sascha, Haas, Stefan, Yatabe, Yasushi ORCID: 0000-0003-1788-559X and Thomas, Roman K. (2014). Functional characterization of recurrent CD74-NRG1 fusions in lung adenocarcinoma. Cancer Res., 74 (19). PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Plenker, Dennis, Lorenz, Carina, Bertrand, Miriam, Riedel, Richard, de Langen, Joop, Braegelmann, Johannes, Buettner, Reinhard, Wolf, Juergen, Thomas, Roman K., Heuckmann, Johannes and Sos, Martin L. (2018). Targeting structural RET and MET kinase alterations in lung adenocarcinoma patients. Cancer Res., 78 (13). PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Plenker, Dennis, Riedel, Maximilian, Braegelmann, Johannes, Dammert, Marcel A., Chauhan, Rakhee, Knowles, Phillip P., Lorenz, Carina, Keul, Marina, Buehrmann, Mike, Pagel, Oliver, Tischler, Verena ORCID: 0000-0002-6673-8329, Scheel, Andreas H., Schtte, Daniel, Song, Yanrui, Stark, Justina, Mrugalla, Florian ORCID: 0000-0002-6281-6051, Alber, Yannic, Richters, Andre, Engel, Julian, Leenders, Frauke, Heuckmann, Johannes M., Wolf, Juergen, Diebold, Joachim, Pall, Georg, Peifer, Martin ORCID: 0000-0002-5243-5503, Aerts, Maarten, Gevaert, Kris ORCID: 0000-0002-4237-0283, Zahedi, Rene P., Buettner, Reinhard, Shokat, Kevan M., McDonald, Neil Q., Kast, Stefan M., Gautschi, Oliver, Thomas, Roman K. and Sos, Martin L. (2017). Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors. Sci. Transl. Med., 9 (394). WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1946-6242

Scheel, Andreas H., Schmitz, Katja, Wilsberg, Lea, Fischer, Rieke N., Merkelbach-Bruse, Sabine, Binot, Elke, Plenker, Dennis, Wolf, Juergen, Tsuta, Koji, Kohno, Takashi, Thomas, Roman K., Schildhaus, Hans-Ulrich and Buettner, Reinhard (2015). Prevalence of NRG1 fusions in Caucasian NSCLC patients determined by fluorescence in situ hybridisation. J. Thorac. Oncol., 10 (9). S. S702 - 1. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1556-1380

Schoettle, Jakob, Chatterjee, Sampurna, Volz, Caroline, Siobal, Maike, Florin, Alexandra, Rokitta, Dennis, Hinze, Yvonne, Dietlein, Felix, Plenker, Dennis, Koenig, Katharina, Albus, Kerstin, Heuckmann, Johannes M., Rauh, Daniel ORCID: 0000-0002-1970-7642, Franz, Thomas, Neumaier, Bernd ORCID: 0000-0001-5425-3116, Fuhr, Uwe, Heukamp, Lukas C. and Ullrich, Roland T. (2015). Intermittent high-dose treatment with erlotinib enhances therapeutic efficacy in EGFR-mutant lung cancer. Oncotarget, 6 (36). S. 38458 - 38469. ORCHARD PARK: IMPACT JOURNALS LLC. ISSN 1949-2553

Thesis

Plenker, Dennis (2015). Functional analysis of CD74-NRG1 - a new recurrent oncogenic gene fusion in lung adenocarcinoma. PhD thesis, Universität zu Köln.