Universität zu Köln

Journal Article

Androulidaki, Ariadne, Wachsmuth, Laurens, Polykratis, Apostolos ORCID: 0000-0001-6720-3302 and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2018). Differential role of MyD88 and TRIF signaling in myeloid cells in the pathogenesis of autoimmune diabetes. PLoS One, 13 (3). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

Carnevalli, Larissa S., Scognamiglio, Roberta, Cabezas-Wallscheid, Nina, Rahmig, Susann, Laurenti, Elisa ORCID: 0000-0002-9917-9092, Masuda, Kohei, Joeckel, Lars, Kuck, Andrea, Sujer, Stefanie, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Erlacher, Miriam, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Essers, Marieke A. G. and Trumpp, Andreas ORCID: 0000-0002-6212-3466 (2014). Improved HSC reconstitution and protection from inflammatory stress and chemotherapy in mice lacking granzyme B. J. Exp. Med., 211 (5). S. 769 - 780. NEW YORK: ROCKEFELLER UNIV PRESS. ISSN 1540-9538

Dannappel, Marius, Vlantis, Katerina, Kumari, Snehlata, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Kim, Chun ORCID: 0000-0001-9497-708X, Wachsmuth, Laurens, Eftychi, Christina, Lin, Juan, Corona, Teresa, Hermance, Nicole, Zelic, Matija, Kirsch, Petra, Basic, Marijana, Bleich, Andre, Kelliher, Michelle and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2014). RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature, 513 (7516). S. 90 - 107. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Imai, Takashi, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Polykratis, Apostolos (2022). Smooth muscle cell specific NEMO deficiency inhibits atherosclerosis in ApoE(-/-) mice. Sci Rep, 12 (1). BERLIN: NATURE PORTFOLIO. ISSN 2045-2322

Koliaraki, Vasiliki ORCID: 0000-0003-1694-6987, Chalkidi, Niki, Henriques, Ana, Tzaferis, Christos, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Waisman, Ari, Muller, Werner ORCID: 0000-0002-1297-9725, Hackam, David J., Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kollias, George (2019). Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis. Cell Reports, 26 (3). S. 536 - 550. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

Kondylis, Vangelis ORCID: 0000-0002-6970-8731, Polykratis, Apostolos, Ehlken, Hanno, Ochoa-Callejero, Laura ORCID: 0000-0001-5366-6613, Straub, Beate Katharina, Krishna-Subramanian, Santosh, Van, Trieu-My, Curth, Harald-Morten, Heise, Nicole, Weih, Falk, Klein, Ulf, Schirmacher, Peter, Kelliher, Michelle and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2015). NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis. Cancer Cell, 28 (5). S. 582 - 599. CAMBRIDGE: CELL PRESS. ISSN 1878-3686

Lin, Juan, Kumari, Snehlata, Kim, Chun ORCID: 0000-0001-9497-708X, Van, Trieu-My, Wachsmuth, Laurens, Polykratis, Apostolos ORCID: 0000-0001-6720-3302 and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2016). RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation. Nature, 540 (7631). S. 124 - 137. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Najjar, Malek, Saleh, Danish, Zelic, Matija, Nogusa, Shoko, Shah, Saumil, Tai, Albert, Finger, Joshua N., Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Gough, Peter J., Bertin, John, Whalen, Michael J., Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Balachandran, Siddharth, Kelliher, Michelle, Poltorak, Alexander and Degterev, Alexei (2016). RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4. Immunity, 45 (1). S. 46 - 60. CAMBRIDGE: CELL PRESS. ISSN 1097-4180

Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Hermance, Nicole, Zelic, Matija, Roderick, Justine, Kim, Chun ORCID: 0000-0001-9497-708X, Lee, Thomas H., Chan, Francis K. M., Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kelliher, Michelle A. (2014). Cutting Edge: RIPK1 Kinase Inactive Mice Are Viable and Protected from TNF-Induced Necroptosis In Vivo. J. Immunol., 193 (4). S. 1539 - 1544. BETHESDA: AMER ASSOC IMMUNOLOGISTS. ISSN 1550-6606

Polykratis, Apostolos ORCID: 0000-0001-6720-3302, van Loo, Geert, Xanthoulea, Sofia, Hellmich, Martin ORCID: 0000-0001-5174-928X and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2012). Conditional Targeting of Tumor Necrosis Factor Receptor-Associated Factor 6 Reveals Opposing Functions of Toll-Like Receptor Signaling in Endothelial and Myeloid Cells in a Mouse Model of Atherosclerosis. Circulation, 126 (14). S. 1739 - 1770. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1524-4539

Roderick, Justine E., Hermance, Nicole, Zelic, Matija, Simmons, Matthew J., Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kelliher, Michelle A. (2014). Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis. Proc. Natl. Acad. Sci. U. S. A., 111 (40). S. 14436 - 14442. WASHINGTON: NATL ACAD SCIENCES. ISSN 0027-8424

Roderick, Justine R., Hermance, Nicole C., Zelic, Matija, Polykratis, Apostolos, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kelliher, Michelle A. (2015). Hematopoietic RIPK1 deficiency results in bone marrow failure due to apoptosis and RIPK3-mediated necroptosis. Clin. Cancer Res., 21. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Saleh, Danish, Najjar, Malek, Zelic, Matija, Shah, Saumil, Nogusa, Shoko, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Paczosa, Michelle K., Gough, Peter J., Bertin, John, Whalen, Michael, Fitzgerald, Katherine A., Slavov, Nikolai ORCID: 0000-0003-2035-1820, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Balachandran, Siddharth, Kelliher, Michelle, Mecsas, Joan and Degterev, Alexei (2017). Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-beta Synthesis Induced by Lipopolysaccharide. J. Immunol., 198 (11). S. 4435 - 4448. BETHESDA: AMER ASSOC IMMUNOLOGISTS. ISSN 1550-6606

Van, Trieu-My, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Straub, Beate Katharina, Kondylis, Vangelis ORCID: 0000-0002-6970-8731, Papadopoulou, Nikoletta and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2017). Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis. J. Clin. Invest., 127 (7). S. 2662 - 2678. ANN ARBOR: AMER SOC CLINICAL INVESTIGATION INC. ISSN 1558-8238

Vlantis, Katerina, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Welz, Patrick-Simon ORCID: 0000-0001-8370-625X, van Loo, Geert, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Wullaert, Andy ORCID: 0000-0001-5012-654X (2016). TLR-independent anti-inflammatory function of intestinal epithelial TRAF6 signalling prevents DSS-induced colitis in mice. Gut, 65 (6). S. 935 - 944. LONDON: BMJ PUBLISHING GROUP. ISSN 1468-3288

Vlantis, Katerina, Wullaert, Andy ORCID: 0000-0001-5012-654X, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Kondylis, Vangelis ORCID: 0000-0002-6970-8731, Dannappel, Marius, Schwarzer, Robin, Welz, Patrick, Corona, Teresa, Walczak, Henning ORCID: 0000-0002-6312-4591, Weih, Falk, Klein, Ulf, Kelliher, Michelle and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2016). NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-kappa B-Dependent and -Independent Functions. Immunity, 44 (3). S. 553 - 568. CAMBRIDGE: CELL PRESS. ISSN 1097-4180