Universität zu Köln

2025

Ahmad, Waleed K.M. ORCID: 0009-0000-2167-8951, Bedau, Tillmann ORCID: 0000-0001-7510-2261, Wang, Yuan, Michels, Sebastian ORCID: 0000-0003-3164-870X, Rasokat, Anna ORCID: 0009-0008-7850-6374, Wolf, Jürgen ORCID: 0000-0001-8833-8812, Heldwein, Matthias ORCID: 0000-0002-2084-795X, Schallenberg, Simon, Quaas, Alexander ORCID: 0000-0002-3537-6011, Büttner, Reinhard ORCID: 0000-0001-8806-4786 and Tolkach, Yuri ORCID: 0000-0001-5239-2841 (2025). Development and clinical validation of a prognostic algorithm for stroma-tumor ratio quantification in non-small cell lung cancer. Lung Cancer, 205. pp. 1-10. Elsevier. ISSN 0169-5002

Barroso, Vincenzo Mitchell ORCID: 0009-0006-7961-089X, Weng, Zhilong ORCID: 0009-0002-0321-9406, Glamann, Lennert, Bauer, Marcus, Wickenhauser, Claudia, Zander, Thomas ORCID: 0000-0002-4266-6818, Büttner, Reinhard ORCID: 0000-0001-8806-4786, Quaas, Alexander ORCID: 0000-0002-3537-6011 and Tolkach, Yuri ORCID: 0000-0001-5239-2841 (2025). Artificial Intelligence–Based Single-Cell Analysis as a Next-Generation Histologic Grading Approach in Colorectal Cancer: Prognostic Role and Tumor Biology Assessment. Modern Pathology, 38 (7). pp. 1-11. Elsevier. ISSN 08933952

Grothey, Bastian ORCID: 0000-0002-0883-6481, Odenkirchen, Jan, Brkic, Adnan, Schömig-Markiefka, Birgid ORCID: 0000-0003-1893-8796, Quaas, Alexander ORCID: 0000-0002-3537-6011, Büttner, Reinhard ORCID: 0000-0001-8806-4786 and Tolkach, Yuri ORCID: 0000-0001-5239-2841 (2025). Comprehensive testing of large language models for extraction of structured data in pathology. Communications Medicine, 5 (1). ISSN 2730-664X

Kessler, Carolina, von Brandenstein, Melanie ORCID: 0000-0002-1499-7644, Klümper, Niklas, Krausewitz, Philipp, Storz, Enno ORCID: 0009-0002-8250-5522, Rieger, Constantin ORCID: 0009-0000-3993-7974, Sperber, Laurenz, Paffenholz, Pia ORCID: 0000-0002-8209-7795, Tolkach, Yuri ORCID: 0000-0001-5239-2841, Wirtz, Ralph, Eckstein, Markus, Heidenreich, Axel ORCID: 0000-0002-2511-3664 and Weiten, Richard ORCID: 0009-0002-7216-1033 (2025). TROP-2 overexpression in papillary renal cell carcinoma supports its potential as a therapeutic target for antibody-drug-conjugate therapy. World Journal of Urology, 43 (1). pp. 1-8. Springer Nature. ISSN 1433-8726

Pak, Svetlana, Simon, Adrian Georg ORCID: 0000-0002-2709-863X, Lyu, Su Ir ORCID: 0009-0002-4125-6048, Tolkach, Yuri ORCID: 0000-0001-5239-2841, Alakus, Hakan ORCID: 0000-0002-3889-3276, Zander, Thomas ORCID: 0000-0002-4266-6818, Buettner, Reinhard ORCID: 0000-0001-8806-4786, Bruns, Christiane Josephine ORCID: 0000-0001-6590-8181, Schroeder, Wolfgang ORCID: 0000-0002-8700-069X and Quaas, Alexander ORCID: 0000-0002-3537-6011 (2025). The expression of the tight junction protein and therapeutical target Claudin 18.2 is heterogeneously distributed within esophageal and gastric adenocarcinoma. Scientific Reports, 15 (1). pp. 1-11. Springer Nature. ISSN 2045-2322

Wang, Yuan, Lami, Kris, Ahmad, Waleed, Schallenberg, Simon, Bychkov, Andrey, Ye, Yuanzi, Jonigk, Danny, Zhu, Xiaoya, Campelos, Sofia, Schultheis, Anne, Heldwein, Matthias ORCID: 0000-0002-2084-795X, Quaas, Alexander ORCID: 0000-0002-3537-6011, Ryska, Ales, Moreira, Andre L., Fukuoka, Junya, Büttner, Reinhard ORCID: 0000-0001-8806-4786 and Tolkach, Yuri ORCID: 0000-0001-5239-2841 (2025). AI Algorithm for Lung Adenocarcinoma Pattern Quantification (PATQUANT): International Validation and Advanced Risk Stratification Superior to Conventional Grading. MedComm, 6 (9). pp. 1-14. Wiley. ISSN 2688-2663

2024

Kludt, Carina, Wang, Yuan, Ahmad, Waleed, Bychkov, Andrey, Fukuoka, Junya, Gaisa, Nadine, Kühnel, Mark, Jonigk, Danny, Pryalukhin, Alexey, Mairinger, Fabian, Klein, Franziska, Schultheis, Anne Maria, Seper, Alexander, Hulla, Wolfgang, Brägelmann, Johannes, Michels, Sebastian, Klein, Sebastian, Quaas, Alexander, Büttner, Reinhard and Tolkach, Yuri (2024). Next-generation lung cancer pathology: Development and validation of diagnostic and prognostic algorithms. Cell Reports Medicine, 5 (9). pp. 1-20. Elsevier. ISSN 2666-3791

2023

Scheel, Andreas H., Lamberty, Hannah, Tolkach, Yuri ORCID: 0000-0001-5239-2841, Gebauer, Florian ORCID: 0000-0001-5312-4814, Schömig-Markiefka, Birgid ORCID: 0000-0003-1893-8796, Zander, Thomas ORCID: 0000-0002-4266-6818, Büttner, Reinhard ORCID: 0000-0001-8806-4786, Rueschoff, Josef, Bruns, Christiane J. ORCID: 0000-0001-6590-8181, Schröder, Wolfgang ORCID: 0000-0002-8700-069X and Quaas, Alexander ORCID: 0000-0002-3537-6011 (2023). Tumour area infiltration and cell count in endoscopic biopsies of therapy-naive upper GI tract carcinomas by QuPath analysis: implications for predictive biomarker testing. Scientific Reports, 13 (1). p. 17580. Springer Nature. ISSN 2045-2322

Tolkach, Yuri ORCID: 0000-0001-5239-2841, Ovtcharov, Vlado, Pryalukhin, Alexey, Eich, Marie-Lisa ORCID: 0000-0002-8601-4598, Gaisa, Nadine Therese, Braun, Martin, Radzhabov, Abdukhamid ORCID: 0000-0003-1948-5792, Quaas, Alexander ORCID: 0000-0002-3537-6011, Hammerer, Peter, Dellmann, Ansgar, Hulla, Wolfgang, Haffner, Michael C., Reis, Henning, Fahoum, Ibrahim, Samarska, Iryna ORCID: 0000-0003-4092-0672, Borbat, Artem ORCID: 0000-0002-9699-8375, Pham, Hoa, Heidenreich, Axel ORCID: 0000-0002-2511-3664, Klein, Sebastian ORCID: 0000-0002-2188-9377, Netto, George, Caie, Peter and Büttner, Reinhard ORCID: 0000-0001-8806-4786 (2023). An international multi-institutional validation study of the algorithm for prostate cancer detection and Gleason grading. npj Precision Oncology, 7 (1). p. 77. Springer Nature. ISSN 2397-768X