Universität zu Köln

Aoki, Shuichi, Inoue, Koetsu, Klein, Sebastian ORCID: 0000-0002-2188-9377, Halvorsen, Stefan, Chen, Jiang, Matsui, Aya, Nikmaneshi, Mohammad R., Kitahara, Shuji ORCID: 0000-0002-2904-0319, Hato, Tai ORCID: 0000-0002-1319-505X, Chen, Xianfeng ORCID: 0000-0002-7531-5862, Kawakubo, Kazumichi ORCID: 0000-0002-8979-9474, Nia, Hadi T., Chen, Ivy, Schanne, Daniel H., Mamessier, Emilie ORCID: 0000-0002-3516-0093, Shigeta, Kohei ORCID: 0000-0003-1596-4200, Kikuchi, Hiroto, Ramjiawan, Rakesh R., Schmidt, Tyge C. E., Iwasaki, Masaaki, Yau, Thomas, Hong, Theodore S., Quaas, Alexander, Plum, Patrick S. ORCID: 0000-0002-8165-4553, Dima, Simona, Popescu, Irinel, Bardeesy, Nabeel, Munn, Lance L., Borad, Mitesh J., Sassi, Slim, Jain, Rakesh K., Zhu, Andrew X. and Duda, Dan G. (2022). Placental growth factor promotes tumour desmoplasia and treatment resistance in intrahepatic cholangiocarcinoma. Gut, 71 (1). S. 185 - 194. LONDON: BMJ PUBLISHING GROUP. ISSN 1468-3288

Fluemann, Ruth, Rehkaemper, Tim, Nieper, Pascal, Pfeiffer, Pauline, Holzem, Alessandra, Klein, Sebastian ORCID: 0000-0002-2188-9377, Bhatia, Sanil ORCID: 0000-0001-6494-7744, Kochanek, Moritz, Kisis, Ilmars ORCID: 0000-0001-6207-3991, Pelzer, Benedikt W., Ahlert, Heinz, Hauer, Julia, Guerreiro, Alexandra da Palma, Ryan, Jeremy A., Reimann, Maurice, Riabinska, Arina, Wiederstein, Janica, Krueger, Marcus, Deckert, Martina, Altmueller, Janine, Klatt, Andreas R., Frenzel, Lukas P., Pasqualucci, Laura, Beguelin, Wendy, Melnick, Ari M., Sander, Sandrine, Montesinos-Rongen, Manuel ORCID: 0000-0003-4724-5526, Brunn, Anna, Lohneis, Philipp, Buettner, Reinhard, Kashkar, Hamid, Borkhardt, Arndt, Letai, Anthony, Persigehl, Thorsten, Peifer, Martin, Schmitt, Clemens A. ORCID: 0000-0002-4731-2226, Reinhardt, Hans Christian and Knittel, Gero ORCID: 0000-0001-8395-3701 (2021). An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities. Blood Cancer Discov., 2 (1). S. 70 - 92. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 2643-3249

Thelen, Martin ORCID: 0000-0002-2785-9726, Wennhold, Kerstin, Lehmann, Jonas, Garcia-Marquez, Maria, Klein, Sebastian ORCID: 0000-0002-2188-9377, Kochen, Elena ORCID: 0000-0003-2470-825X, Lohneis, Philipp, Lechner, Axel, Wagener-Ryczek, Svenja, Plum, Patrick Sven, Velazquez Camacho, Oscar, Pfister, David, Doerr, Fabian, Heldwein, Matthias, Hekmat, Khosro, Beutner, Dirk, Klussmann, Jens Peter, Thangarajah, Fabinshy, Ratiu, Dominik, Malter, Wolfram, Merkelbach-Bruse, Sabine, Bruns, Christiane Josephine, Quaas, Alexander, von Bergwelt-Baildon, Michael and Schloesser, Hans A. (2021). Cancer-specific immune evasion and substantial heterogeneity within cancer types provide evidence for personalized immunotherapy. npj Precis. Oncol., 5 (1). BERLIN: NATURE RESEARCH. ISSN 2397-768X

Klein, Sebastian ORCID: 0000-0002-2188-9377, Quaas, Alexander, Quantius, Jennifer, Loeser, Heike, Meinel, Jorn, Peifer, Martin, Wagner, Steffen ORCID: 0000-0003-0873-1601, Gattenloehner, Stefan, Wittekindt, Claus, Doeberitz, Magnus von Knebel, Prigge, Elena-Sophie, Langer, Christine, Noh, Ka-Won, Maltseva, Margaret, Reinhardt, Hans Christian, Buettner, Reinhard, Klussmann, Jens Peter ORCID: 0000-0002-8223-7954 and Wuerdemann, Nora (2021). Deep Learning Predicts HPV Association in Oropharyngeal Squamous Cell Carcinomas and Identifies Patients with a Favorable Prognosis Using Regular H&E Stains. Clin. Cancer Res., 27 (4). S. 1131 - 1139. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Braegelmann, Johannes, Lorenz, Carina, Borchmann, Sven ORCID: 0000-0001-6662-6864, Nishii, Kazuya, Wegner, Julia ORCID: 0000-0001-8103-8040, Meder, Lydia, Ostendorp, Jenny, Ast, David F., Heimsoeth, Alena, Nakasuka, Takamasa, Hirabae, Atsuko, Okawa, Sachi, Dammert, Marcel A., Plenker, Dennis, Klein, Sebastian ORCID: 0000-0002-2188-9377, Lohneis, Philipp, Gu, Jianing, Godfrey, Laura K., Forster, Jan, Trajkovic-Arsic, Marija, Zillinger, Thomas, Haarmann, Mareike, Quaas, Alexander, Lennartz, Stefanie, Schmiel, Marcel, D'Rozario, Joshua, Thomas, Emily S., Li, Henry, Schmitt, Clemens A. ORCID: 0000-0002-4731-2226, George, Julie, Thomas, Roman K., von Karstedt, Silvia, Hartmann, Gunther, Buettner, Reinhard, Ullrich, Roland T., Siveke, Jens T., Ohashi, Kadoaki, Schlee, Martin ORCID: 0000-0003-3671-7639 and Sos, Martin L. (2021). MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I. Nat. Commun., 12 (1). BERLIN: NATURE PORTFOLIO. ISSN 2041-1723

Klein, Sebastian ORCID: 0000-0002-2188-9377 and Duda, Dan G. ORCID: 0000-0001-7065-8797 (2021). Machine Learning for Future Subtyping of the Tumor Microenvironment of Gastro-Esophageal Adenocarcinomas. Cancers, 13 (19). BASEL: MDPI. ISSN 2072-6694

Quaas, Alexander, Pamuk, Aylin, Klein, Sebastian ORCID: 0000-0002-2188-9377, Quantius, Jennifer, Rehkaemper, Jan, Barutcu, Atakan G., Rueschoff, Josef, Zander, Thomas, Gebauer, Florian, Hillmer, Axel, Buettner, Reinhard, Schroeder, Wolfgang, Bruns, Christiane J., Loeser, Heike, Schoemig-Markiefka, Birgid and Alakus, Hakan (2021). Sex-specific prognostic effect of CD66b-positive tumor-infiltrating neutrophils (TANs) in gastric and esophageal adenocarcinoma. Gastric Cancer, 24 (6). S. 1213 - 1227. NEW YORK: SPRINGER. ISSN 1436-3305

Noh, Ka-Won, Buettner, Reinhard and Klein, Sebastian ORCID: 0000-0002-2188-9377 (2021). Shifting Gears in Precision Oncology-Challenges and Opportunities of Integrative Data Analysis. Biomolecules, 11 (9). BASEL: MDPI. ISSN 2218-273X

Klein, Sebastian ORCID: 0000-0002-2188-9377, Mauch, Cornelia, Brinker, Klaus, Noh, Ka-Won, Knez, Sonja, Buettner, Reinhard, Quaas, Alexander and Helbig, Doris (2021). Tumor infiltrating lymphocyte clusters are associated with response to immune checkpoint inhibition in BRAF V600(E/K) mutated malignant melanomas. Sci Rep, 11 (1). BERLIN: NATURE PORTFOLIO. ISSN 2045-2322

Klein, Sebastian ORCID: 0000-0002-2188-9377, Gildenblat, Jacob, Ihle, Michaele Angelika, Merkelbach-Bruse, Sabine, Noh, Ka-Won, Peifer, Martin, Quaas, Alexander and Buettner, Reinhard (2020). Deep learning for sensitive detection of Helicobacter Pylori in gastric biopsies. BMC Gastroenterol., 20 (1). LONDON: BMC. ISSN 1471-230X

Klein, Sebastian ORCID: 0000-0002-2188-9377, Quaas, Alexander, Noh, Ka-Won, Cartolano, Maria, Abedpour, Nima, Mauch, Cornelia, Quantius, Jennifer, Reinhardt, Hans Christian, Buettner, Reinhard, Peifer, Martin and Helbig, Doris (2020). Integrative Analysis of Pleomorphic Dermal Sarcomas Reveals Fibroblastic Differentiation and Susceptibility to Immunotherapy. Clin. Cancer Res., 26 (21). S. 5638 - 5646. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Klein, Sebastian ORCID: 0000-0002-2188-9377, Mentrup, Birgit, Timmen, Melanie, Sherwood, Joanna, Lindemann, Otto, Fobker, Manfred, Kronenberg, Daniel ORCID: 0000-0001-6807-7328, Pap, Thomas, Raschke, Michael J. and Stange, Richard ORCID: 0000-0003-0807-3151 (2020). Modulation of Transient Receptor Potential Channels 3 and 6 Regulates Osteoclast Function with Impact on Trabecular Bone Loss. Calcif. Tissue Int., 106 (6). S. 655 - 665. NEW YORK: SPRINGER. ISSN 1432-0827

Duda, Dan G., Dima, Simona O., Cucu, Dana, Sorop, Andrei, Klein, Sebastian ORCID: 0000-0002-2188-9377, Ancukiewicz, Marek, Kitahara, Shuji ORCID: 0000-0002-2904-0319, Iacob, Speranta, Bacalbasa, Nicolae, Tomescu, Dana ORCID: 0000-0001-9673-5754, Herlea, Vlad, Tanase, Cristiana, Croitoru, Adina and Popescu, Irinel (2020). Potential Circulating Biomarkers of Recurrence after Hepatic Resection or Liver Transplantation in Hepatocellular Carcinoma Patients. Cancers, 12 (5). BASEL: MDPI. ISSN 2072-6694

Shigeta, Kohei, Matsui, Aya, Kikuchi, Hiroto, Klein, Sebastian ORCID: 0000-0002-2188-9377, Mamessier, Emilie, Chen, Ivy X., Aoki, Shuichi, Kitahara, Shuji ORCID: 0000-0002-2904-0319, Inoue, Koetsu, Shigeta, Ayako, Hato, Tai, Ramjiawan, Rakesh R., Staiculescu, Daniel, Zopf, Dieter, Fiebig, Lukas, Hobbs, Gabriela S., Quaas, Alexander, Dima, Simona, Popescu, Irinel, Huang, Peigen, Munn, Lance L., Cobbold, Mark, Goyal, Lipika, Zhu, Andrew X., Jain, Rakesh K. and Duda, Dan G. (2020). Regorafenib combined with PD1 blockade increases CD8 T-cell infiltration by inducing CXCL10 expression in hepatocellular carcinoma. J. Immunother. Cancer, 8 (2). LONDON: BMJ PUBLISHING GROUP. ISSN 2051-1426

Shostak, Kateryna, Jiang, Zheshen, Charloteaux, Benoit, Mayer, Alice, Habraken, Yvette, Tharun, Lars, Klein, Sebastian ORCID: 0000-0002-2188-9377, Xu, Xinyi, Vislovukh, Andrii, Close, Pierre, Florin, Alexandra, Rambow, Florian, Marine, Jean-Christophe ORCID: 0000-0003-2433-9837, Buettner, Reinhard and Chariot, Alain (2020). The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage. Nat. Commun., 11 (1). LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723