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Manrubia, Susanna ORCID: 0000-0003-0134-2785, Cuesta, Jose A., Aguirre, Jacobo, Ahnert, Sebastian E., Altenberg, Lee, Cano, Alejandro V., Catalan, Pablo ORCID: 0000-0003-2826-4684, Diaz-Uriarte, Ramon ORCID: 0000-0002-6637-9039, Elena, Santiago F., Garcia-Martin, Juan Antonio ORCID: 0000-0003-0993-4064, Hogeweg, Paulien, Khatri, Bhavin S., Krug, Joachim, Louis, Ard A., Martin, Nora S., Payne, Joshua L., Tarnowski, Matthew J. and Weiss, Marcel (2022). The long and winding road to understanding organismal construction Reply to comments on From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics comment. Phys. Life Rev., 42. S. 19 - 25. AMSTERDAM: ELSEVIER. ISSN 1873-1457